Protein Alignment CG4465 and oct-2

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_509899.3
• Gene: oct-2 / 181325
• WormBaseID: WBGene00003843
• Length: 757
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 128/595 - (21%)
• Similarity: 231/595 - (38%)
• Gaps: 142/595 - (23%)

  Fly    45 TPHPKANNLADDNDDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFT--APD------L 101
            |...:|..|. |.|.:.|..::|....||:...||:.:.::|.|.|...:::.  .||      .
 Worm   143 TKETRAKRLT-DIDFEGILQLIGGCSYWQIIVYLIISVQQVPHAMFNLSVVYMMYQPDHWCKIPF 206

  Fly   102 YPEEEYKCDT--TAFGPD--VNSTVSL-------------DHCYVMVNYGESAYA---------- 139
            :.||.:..:.  |.:..|  :|||::.             |.|:    |.|..|.
 Worm   207 FNEESFSAELGYTNYTWDQVLNSTIAFPRTFNKQRNELHHDQCH----YFERDYVHIKLSPWAQV 267

  Fly   140 --------MRQCRKFLYTTGFHSLTMEFDLVCLCDFFVAWSQ--------YWHLFGLLIGGVAAT 188
                    :.:|:::.|.|.....|:..:...:||  ..||:        ..:|.|..:||
 Worm   268 KDMNATGKINRCKEWEYDTSVMDRTIVTEWNRVCD--NNWSRAHVHMSYSLGYLVGCFVGG---- 326

  Fly   189 KLMRVLSPRQIYRTGIWCLLMCSLLMGLV----KDFSLHCGLRCLAAVSCCFMITSGQYIFGDIT 249
                .:|.|...:|.|....:.::|.|.:    |:|.:...:|.|.|.:......:...:..::|
 Worm   327 ----FISDRYGRKTAITGFGILTMLFGFLLTYSKEFEIFLVVRFLLAATNEAADLAAYVLCMEVT 387

  Fly   250 AGKYR--VGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQL- 311
            ..|||  ||:||  ...||.|...|..:|....||..|:|...|..::.:.||.:.|:||||.:
 Worm   388 GTKYRSIVGSLI--QAPWACGYAFLALIAYLTKSWTMIHLICVLLHIISLMLLYFLPESPRWLIL 450

  Fly   312 -QHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWM--GQR 373
             ..||:|:       .|:.||...|      ...||..|..:|....:.         ||  .::
 Worm   451 NNKTKQAE-------KIIREACHYN------KSRLPSDLGLVRHAEKKK---------WMKHNEK 493

  Fly   374 RSTFHL----------VAVHMALATFMVVNTGLLLHV--------RSFGREHLVSNTL--AMGLA 418
            .|.|||          |.:.:......:|..|:::.:        |.|.....::|.:  |:.|.
 Worm   494 PSYFHLFRSSELRFRNVVLFIVWIATALVYYGMVIALSDQSSPGRRVFDGNFFLNNAMAGAIELP 558

  Fly   419 EMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVY--GLTLGLLMASLPQA 481
            .::.|...|.:....|:....:..|..::...:             .||  ..||.|:...|.:|
 Worm   559 TLVFCVFLLRMGRKRSQMLVLFGSGLFLLTSVV-------------MVYRKQSTLALIFMLLSKA 610

  Fly   482 AVACAQSMILACLGELVP-MEQRSCLSFSAVTWARVWQLSASFLTLLRQVS-PALSLSAFCLLVI 544
            .:..:.:::.....||.| :.:.|.:..|::. ||:...::.::.:|..|: |.:.::.|....:
 Worm   611 CIQGSFNILYIFTSELNPTVVRNSAVGISSMV-ARMGAGASGYIAILSDVTMPLVPMTIFACFSL 674

  Fly   545 LGGLGTCCLV 554
            |.|    |||
 Worm   675 LAG----CLV 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	119/570 (21%)
		MFS	169..>303	CDD:119392	37/147 (25%)
oct-2	NP_509899.3	MFS_SLC22	281..673	CDD:340875	94/439 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163017
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950