DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4465 and Ust5r

DIOPT Version :9

Sequence 1:	NP_650847.1	Gene:	CG4465 / 42374	FlyBaseID:	FBgn0038750	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	571	Identity:	126/571 - (22%)
Similarity:	220/571 - (38%)	Gaps:	133/571 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 MGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKCDTTAFGPDVNSTVSLDHCYVM 130
            :|:.|.:|:..:..:||..:..........|||  ..|  .::|......   |.|||.:|..::
  Rat    10 VGSLGRFQILQMAFVFLINVSVVPHSTIENFTA--AIP--SHRCWVPILD---NVTVSDNHSRIL 67

  Fly   131 VNYG---------ESAYAMRQCRKF-----------------------------LY-TTGFHSLT 156
             |..         :|...:.:||:|                             :| .:.|||.|
  Rat    68 -NQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSVTEADTEPCVDGWVYDRSNFHSTT 131

  Fly   157 M-EFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLL------- 213
            : |:||||......:.:::..:.|..|||:....|..        |.|...:|.|:||
  Rat   132 VTEWDLVCESQVLNSVTKFSFMIGAFIGGIVNGPLSD--------RFGRKFVLKCALLQMAITET 188

  Fly   214 -MGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLAS 277
             :|...:|.::|.||.||.::...::.:...:..:.|:.|:.....::..|..:.|.::|.|||.
  Rat   189 CVGFASNFFIYCSLRFLAGMTFEPILVNSNLLMFEWTSHKFLAMMSVIAPCAGSFGSMILAGLAF 253

  Fly   278 NAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNG------ 336
            ...:|.|:.|.:::.:...:.|..|..:|.|| |..|.:.|..::.    |.:.|..||
  Rat   254 QFQNWHHLQLAMSVPIFFFLILTRWLSESARW-LIVTNKPQKGLKE----LRKVAHMNGMKNSGD 313

  Fly   337 --RMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFH-------LVAVHMALATFMVV 392
              .|..|...:.::||..:.|   |.|            |..||       :.|:......||:.
  Rat   314 NLTMEVVRTSMKRELEAAKAR---PSP------------RDLFHTPILRKRICAMSFMRILFMLS 363

  Fly   393 NTGLLLHVRSFGREHLVSNTLAMG--------LAEMLGCFLALHLTFNLSERKWQWAGGFAIVVG 449
            ..|:.||:     :||.||.:.:.        |..::|.::     ||...|:..     .:||.
  Rat   364 IFGMSLHL-----QHLSSNIMLLQFVVSASSLLFSVIGPYV-----FNRMGRRIT-----QMVVM 413

  Fly   450 CIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWA 514
            .:..|| .|....:|:...: |.:.:.:|..|..|.:..:......||:|...|:    :|:...
  Rat   414 TLRGIC-ILTAVFVPQEMQI-LRITVVTLAGAFSALSFGVNRLHTNELLPTTLRA----TAIGVI 472

  Fly   515 RVWQLSASFLT----LLRQVSPALSLSAFCLLVILGGLGTCCLVTRDKEQP 561
            .::..|..||.    :|...||.|....:....||.|. |..|:...|.||
  Rat   473 GMFGNSGFFLAPLFMILASYSPNLPWIFYGGFSILNGF-TVFLLPETKNQP 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	122/560 (22%)
CG4465	NP_650847.1	MFS	169..>303	CDD:119392	30/141 (21%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	103/456 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347097
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840