Protein Alignment CG4465 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 446
• Identity: 110/446 - (24%)
• Similarity: 152/446 - (34%)
• Gaps: 142/446 - (31%)

  Fly   153 HSLTMEFDLVCLCDFFVAWSQYWHLFGLLIG----GVAATKLMRVLSPRQIYRTGIWCLLMCSLL 213
            |.|:..::|||...:.|...|..||.|.|:|    |....:..|    |.::
Human     3 HQLSQNWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGR----RAVF------------- 50

  Fly   214 MGLVKDFSLHCGLRCLAAVSCCF-MITSGQYIFGDITAGKYRVGTLILY---------------- 261
               |....|..||....|::..| .:...:.:.|...||    ..|.||
Human    51 ---VASLVLTTGLGASEALAASFPTLLVLRLLHGGTLAG----ALLALYLARLELCDPPHRLAFS 108

  Fly   262 ---DCFWALGLILLPGLASNAPSWQHIY-LGVTLSLLVIVFLLPW-----TPDSPRWQLQHTKEA 317
               ..|..:|.:||||||:....|:.:. ||..:|.|:::|   |     .|:||.|.|     |
Human   109 MGAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLF---WGFPALFPESPCWLL-----A 165

  Fly   318 QLAIERTVGILLEAARTN----GRMHKVSKELPQQLEELRERMLEPMPAVH-----------WMH 367
            ...:.|...||...|..:    |........|..:|..|..|  .|.|..|           |.:
Human   166 TGQVARARKILWRFAEASGVGPGDSSLEENSLATELTMLSAR--SPQPRYHSPLGLLRTRVTWRN 228

  Fly   368 -LWMG------------QRRS------TFHL-----VAVHMALATFMVVNTGLLLHVRSFGREH- 407
             |.:|            .|||      ||:|     ..:..|...|      |||.....||..
Human   229 GLILGFSSLVGGGIRASFRRSLAPQVPTFYLPYFLEAGLEAAALVF------LLLTADCCGRRPV 287

  Fly   408 LVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGS-----ICWFLAEEDMPEVY 467
            |:..|:..|||.:|....|.:|.        .|...|..|:|.:.|     :....|.|..|.|.
Human   288 LLLGTMVTGLASLLLLAGAQYLP--------GWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVI 344

  Fly   468 -GLTLGLLMAS--LPQAA----------------VACAQSMILACLGELVPMEQRS 504
             |..|||::.:  |.|||                |..|...:||.|..|:..|.||
Human   345 RGAGLGLVLGAGFLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRS 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	110/446 (25%)
		MFS	169..>303	CDD:119392	37/163 (23%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	100/421 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153492
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930