Protein Alignment CG4465 and Slc22a13

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_598741.2
• Gene: Slc22a13 / 102570
• MGIID: 2143107
• Length: 551
• Species: Mus musculus
• Alignment Length: 543
• Identity: 132/543 - (24%)
• Similarity: 210/543 - (38%)
• Gaps: 96/543 - (17%)

  Fly    66 MGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKC--------------------- 109
            :|:||.:|:|..:::.:....||:|:...:|...|    |.:.|
Mouse    11 VGDFGRFQVRLTILMGIPNFLAAFFIFGQVFMVLD----EAHHCSVSWVKNHTFNLSAAEQLAIS 71

  Fly   110 ---DTTA-------FGPDVNSTV---SLDHCYVMVNYGESAYAMRQCRKFLYTTGFHSLTMEFDL 161
               ||..       |.|..:|..   .|.|.:......:|.:...:.|.       .||..||||
Mouse    72 IPNDTAGRPESCLMFRPPPDSASLEDILSHRFNETQACDSGWDYPENRP-------QSLKKEFDL 129

  Fly   162 VCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPR-----QIYRTGIWCLLMCSLLMGLVKDFS 221
            ||........||...:.|||:|.:....:...:..|     |:..:||     .|:....|..|.
Mouse   130 VCDRKNLKKTSQSVFMAGLLVGALVFGPVCDWIGRRPSLLMQVLLSGI-----TSMATAFVSSFE 189

  Fly   222 LHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQHIY 286
            |:..||.:.|.:....:.|...:..:.....:|...::|.....|||.::|.|||....:|:.:.
Mouse   190 LYLALRFVLATANAGFLLSTNVLISEWVGPSWRTQAVVLAQSNVALGQMVLAGLAYGVRNWRLLQ 254

  Fly   287 LGVTLSLLVIVFLLPWTPDSPRWQLQ--HTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQL 349
            :..|..:|::.|.....|:||||.|.  .|:||:..:::       ||..|||  .:|.||..||
Mouse   255 ITGTAPVLLLFFYFWVLPESPRWLLSQGRTEEAKQLVQK-------AALVNGR--PLSPELLNQL 310

  Fly   350 -EELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVRSFGREHLVSNTL 413
             .|........:......||    |:.|..|:||....:   :|...|...|..||.:..|:. |
Mouse   311 VPEKTGPSGNALDLFRHPHL----RKVTLILIAVWFVDS---LVYYSLSFQVGDFGLDIYVTQ-L 367

  Fly   414 AMGLAEMLGCFLALHLTFNLSERKWQ------WAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLG 472
            ..|..||.|.||::.:...|. |||.      .||...|::        .....|:|     |:.
Mouse   368 IFGAVEMPGRFLSVLMMEKLG-RKWSQLCTLTLAGIMYIII--------IFIPGDLP-----TVV 418

  Fly   473 LLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLS 537
            .::|.:.:.|.|.|.::......||.|...|.........::||..:....:.||.|...|:.:.
Mouse   419 TVLAVVGKFASAAAFTISYVYTAELFPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHQAIPMV 483

  Fly   538 AFCLLVILGGLGTCCLVTRDKEQ 560
            .|..|.|..|| .|.|:...:.|
Mouse   484 IFGSLPIGAGL-LCALLPETRGQ 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	110/423 (26%)
Slc22a13	NP_598741.2	2A0119	12..510	CDD:273328	132/542 (24%)