Protein Alignment CG4465 and slc22a2

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: XP_002933908.1
• Gene: slc22a2 / 100487774
• XenbaseID: XB-GENE-965056
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 556
• Identity: 125/556 - (22%)
• Similarity: 212/556 - (38%)
• Gaps: 126/556 - (22%)

  Fly    59 DDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFT--APDL------YPEEEYKCDTTA-- 113
            |:::.|| |.|..:|.:..::|....:..:.....|:|.  .||.      .||...:|:.|.
 Frog     5 DELLEHI-GEFDAFQKQIFILLCFISVVFSPIYVGIVFLGFVPDYRCVSAGIPEPSNECEWTLNY 68

  Fly   114 FGPDVNSTVSL--DHCYVM-VNYGE-------------SAYAMRQCRK-FLYTTGFHSLTMEFDL 161
            .||: .||.||  ..||.. |::..             |...:..|:. :.|.|...||..||:|
 Frog    69 TGPN-GSTDSLYMSQCYQYDVDWNSTSLNCTNSSLNITSKLPITNCKDGWDYNTTGSSLVTEFNL 132

  Fly   162 VC----LCDFFVAWSQYWHLFGLLIGGVAATKLMR---VLSPRQIYRTGIWCLLMCSLLMGLVKD 219
            ||    ..|||.:........|.||.|..|.:..|   ::|  .|..|||:     .:||....:
 Frog   133 VCGDSWKLDFFQSCVNIGFFIGGLISGYIADRFGRKPFLIS--SILITGIF-----GILMAFAPN 190

  Fly   220 FSLHCGLRCLAAV--SCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSW 282
            :.|....|.:...  ..|::  ||..:..:....::|....|:|...:.:||:||.|:|...|.|
 Frog   191 YPLVVTFRFIQGFVSKGCWL--SGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSGVAYVLPHW 253

  Fly   283 QHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQL-AIERTVGILLEAARTNGRM-------- 338
            :.:.:.||:.....:......|:||||.:...::|:. ||..|:      |:.||:|
 Frog   254 RWLQMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTI------AKKNGKMVPDFLESL 312

  Fly   339 ----HKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLH 399
                ....|::|..|:.:|...:.....: .|::|.                 |..||..|.::|
 Frog   313 TADEEAGEKQVPSFLDLVRTPQIRKHTLI-LMYIWF-----------------TCAVVYQGSIMH 359

  Fly   400 VRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCI--GSICWFLAEED 462
            :.|.. |::..:.....|.|.....|.: :|.:...|::.|      :|.||  |..|  |....
 Frog   360 MGSTA-ENIYFDFFISALVEFPSAILII-VTVDRVGRRYPW------LVCCIITGITC--LITAF 414

  Fly   463 MPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRS-----CLS----------FSAVT 512
            :|..|...: :.::.:.:..:..:..|:.....||.|...|:     |.|          |....
 Frog   415 IPHGYSWLI-ITLSCVSRMGITVSYEMVCLVNAELYPTFIRNLGIMVCSSMCDLGGVITPFIVYR 478

  Fly   513 WARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGL 548
            .|.:||              .|.|..|.:|..:.|:
 Frog   479 LAAIWQ--------------ELPLIVFAVLATVSGI 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	100/446 (22%)
slc22a2	XP_002933908.1	2A0119	12..516	CDD:273328	122/548 (22%)