Protein Alignment RhoGAP92B and RGA1

DIOPT Version :10

• Sequence 1: NP_650844.1
• Gene: RhoGAP92B / 42371
• FlyBaseID: FBgn0038747
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_014770.1
• Gene: RGA1 / 854294
• SGDID: S000005653
• Length: 1007
• Species: Saccharomyces cerevisiae
• Alignment Length: 459
• Identity: 101/459 - (22%)
• Similarity: 180/459 - (39%)
• Gaps: 109/459 - (23%)

  Fly    60 SGSSEEQDKRTKKNSHYKIAQALDESAKEL-PKDMPLQKVLANCGELEKTMAECIIESELETEAK 123
            |.:.|||.:...:||..:...:||   ||: ..:..|:::..|..|||....|
Yeast   579 SDNFEEQKETLYENSESRNDPSLD---KEIVTAEHYLKQLKINLKELESQREE------------ 628

  Fly   124 VVRRLKNILDKEIQEISTLKRNVSRTLQEYTSLKR-----SHEAA--------IRLEEPAAKVNH 175
                    |.|||.|:.::|..:.|.::.|.|.|.     |:|.:        |.|.| :..|.|
Yeast   629 --------LMKEITEMKSMKEALRRHIESYNSEKNKLYLDSNELSNNPPMINEISLGE-SPPVKH 684

  Fly   176 IKSQQ---------------EECELKLEKERDAWAAQMLELIAKEDEIVSC------------IR 213
            :.:..               ...:.:.|:.....:......|.|...::..            |.
Yeast   685 VATASSVARSSVKPKFWKFFSSAKPQTEQSIQGVSTNNTNSIVKSAPVLLSAPSSGSNSGRLEIS 749

  Fly   214 DYVL-NQRNYHERALQHV--NASLARIQDTIQGTEKSR-FGTSLKEHLTSTNREISYIVELCCCC 274
            ..|| |...:.:..|..:  :|::.:.:|..:..:.|. :|:||.......|.||..|:.:|...
Yeast   750 PPVLQNPNEFSDVRLVPIENDANMGQSKDGEEYLDGSNLYGSSLVARCNYENNEIPMILSVCIDF 814

  Fly   275 LL--EHGLEEEGLLRVGCASTKLRRMKHALEA----QHVKTPLPLDYQDPHVIGSILKLYLRELP 333
            :.  |..:..||:.|...:...:..::....|    |:.:||..|..||.:|:..:||.|||:||
Yeast   815 IESDEENMRSEGIYRKSGSQLVIEEIEKQFSAWKVQQNTETPNILTEQDLNVVTGVLKRYLRKLP 879

  Fly   334 EPLLTYNLYKDFIRIAERHSEAER---------------------KTEIKAILTKLPKENYANLR 377
            .|:.|:.:|:..:|:.:.....|.                     |:.:|.||..||:|:|..||
Yeast   880 NPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLR 944

  Fly   378 YLTRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPRIDKSSNAPADYIGQ--VNSSSAANIIVELL 440
            .|:..:..|.:.|..|:|:..|||:|.:|.::           .|:.|:  :......|.||..:
Yeast   945 VLSEHIEKVTRYSHWNRMTLYNLALVFAPGLI-----------RDFSGEKDIIDMKERNYIVAFI 998

  Fly   441 ISQW 444
            ...:
Yeast   999 FGNY 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP92B	NP_650844.1	BAR	27..257	CDD:472257	47/241 (20%)
		RhoGAP_nadrin	245..452	CDD:239851	58/230 (25%)
		PRK13855	495..>650	CDD:172376
RGA1	NP_014770.1	LIM1_Rga	13..67	CDD:188780
		LIM2_Rga	70..123	CDD:188781
		RhoGAP	803..1002	CDD:214618	53/209 (25%)