DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP92B and AT5G22400

DIOPT Version :9

Sequence 1:	NP_001287417.1	Gene:	RhoGAP92B / 42371	FlyBaseID:	FBgn0038747	Length:	740	Species:	Drosophila melanogaster
Sequence 2:	NP_197632.1	Gene:	AT5G22400 / 832301	AraportID:	AT5G22400	Length:	466	Species:	Arabidopsis thaliana

Alignment Length:	364	Identity:	79/364 - (21%)
Similarity:	142/364 - (39%)	Gaps:	92/364 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 FGTSLKEHLTSTNREISYIVELCC----------CCLLEHGLEEEGLLRVGCASTKLRRMKHALE 303
            ||.|      :.:.::||.....|          |...:.||:.||:.|:...:::...::..|.
plant   160 FGVS------TESMQLSYDSRGNCVPTILLLMQNCLYSQGGLQAEGIFRLTAENSEEEAVREQLN 218

  Fly   304 AQHVKTPLPLDYQDPHVIGSILKLYLRELPEPLLTYNLYKDFIRIAERHSEAERKTEIKAILTKL 368
            ...:...:     |.|.:..::|.:.||||..:|      |.:. .|:..:.:.:.|...::..|
plant   219 RGFIPERI-----DVHCLAGLIKAWFRELPTSVL------DSLS-PEQVMQCQTEEENVELVRLL 271

  Fly   369 PKENYANLRYLTRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPRIDKSSNAPADYIGQVNSSSAA 433
            |....|.|.:....::.|.|...||||:|:|:|:|.:|||  .::|....| ..|..||.:
plant   272 PPTEAALLDWAINLMADVVQYEHLNKMNSRNIAMVFAPNM--TQMDDPLTA-LMYAVQVMN---- 329

  Fly   434 NIIVELLISQWDYFFIGEVEFYLTL-QKQKLFVE----------GKSKSNSSNENLDRNDSEVME 487
              .::.||.:             || ::|...||          .:|...|.:::|..|.||..|
plant   330 --FLKTLIEK-------------TLRERQDSVVEQAHAFPLEPSDESGHQSPSQSLAFNTSEQSE 379

  Fly   488 SPRYGTLRRQKANAPSPPTTNGNGIIMTTSQTSHRPHAKELFPQQTPEKQEKPAKPPLPNLPQFQ 552
            .                  |..:.|....:|:|....:.||..:....:|.:      .:..:::
plant   380 E------------------TQSDNIENAENQSSSSEISDELTLENNACEQRE------TDFGKYR 420

  Fly   553 SPAASQPTQTQLEPLPPPPVTPAKPVPMTRTQFFGLDNL 591
            :...|..:|..:..|.||     ...|:.||:  ||.||
plant   421 TGRLSDSSQQVVLNLDPP-----AQWPVGRTK--GLTNL 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP92B	NP_001287417.1	BAR	27..257	CDD:299863	3/7 (43%)
RhoGAP92B	NP_001287417.1	RhoGAP_nadrin	245..452	CDD:239851	48/212 (23%)
AT5G22400	NP_197632.1	CRIB	115..155	CDD:238077
AT5G22400	NP_197632.1	RhoGAP	178..337	CDD:214618	42/179 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4270
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810