DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoGAP92B and arhgap1

DIOPT Version :9

Sequence 1:NP_001287417.1 Gene:RhoGAP92B / 42371 FlyBaseID:FBgn0038747 Length:740 Species:Drosophila melanogaster
Sequence 2:NP_001017781.1 Gene:arhgap1 / 550478 ZFINID:ZDB-GENE-050417-305 Length:434 Species:Danio rerio


Alignment Length:450 Identity:113/450 - (25%)
Similarity:193/450 - (42%) Gaps:100/450 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 GGGGSGSGSSEE----QDKRTKKNSHYKIAQALDE-----SAKELPKDMPLQKVLA--------- 100
            ||..|.|.:.::    |||:...:....::::..:     ....||.|.|...:..         
Zfish    14 GGDDSPSAALDQLKLVQDKQWPPDDPSSLSKSASDIKSLGDTSHLPWDDPFYDIARHQIVEVAGD 78

  Fly   101 -NCGELEKTMAECIIESELETE-AKVVRRLKNILDKEIQEISTL-----------KRNVSRTLQE 152
             |.|........|.:..:.:.: .|::..||..|||.::...||           |.::|.....
Zfish    79 DNFGRKVIVFNACRMPPQHQLDHHKLLMYLKQTLDKYVESDYTLIYFHHGLTSENKPSLSWLRDA 143

  Fly   153 YTSLKRSHEAAIR----------------LEEP------AAKVNHIKSQQEECELKLEKERDAWA 195
            |....|.::..|:                |.:|      ..|:|:|                   
Zfish   144 YREFDRKYKKNIKALYIVHPTMFIRTILILFKPIISFKFGRKINYI------------------- 189

  Fly   196 AQMLELIAKEDEIVSCIRDYVLNQ-RNYHERALQHVNASLARIQDTIQGTEK-----SRFGTSLK 254
                ..:::.:|||.|.:..:.|: |.|.::....:..|:  :...|.....     .:||.||.
Zfish   190 ----NYLSELEEIVKCDQLVIPNRVREYDDKIRLSLKPSV--VPGPISPPRSPPLPFQQFGVSLT 248

  Fly   255 --EHLTSTNREISYIVELCCCCLLEHGLEEEGLLRVGCASTKLRRMKHALEA-QHVKTPLPLDYQ 316
              :|..:.:..|..::......|||:||:.||:.|.....:.::.:|....: :.|...   ..:
Zfish   249 TLKHRAADSEGIPLVMRDTIGFLLENGLQTEGIFRRSANVSLVKDVKAKYNSGEEVNFS---QLE 310

  Fly   317 DPHVIGSILKLYLRELPEPLLTYNLYKDFIRI--AERHSEAERKTEIKAILTKLPKENYANLRYL 379
            |.|:...|||::|||||||||||.||.|.:..  .:..|:|||   |:.:|..||.||||:||:|
Zfish   311 DVHLAAVILKMFLRELPEPLLTYQLYNDIVNFHNVDIESQAER---IQNMLMSLPDENYASLRFL 372

  Fly   380 TRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPRIDKSSNAPADYIGQVNSSSAANIIVEL 439
            .:||:.|...|.:|||::.|||:|..||:||.: |.|....|  ||.:|:.:  .::::|
Zfish   373 VQFLAQVSAESEINKMTNANLAVVFGPNLLWAQ-DASMTLSA--IGLINNFT--RVLLDL 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoGAP92BNP_001287417.1 BAR 27..257 CDD:299863 45/263 (17%)
RhoGAP_nadrin 245..452 CDD:239851 71/204 (35%)
arhgap1NP_001017781.1 CRAL_TRIO_2 82..204 CDD:290435 24/144 (17%)
RhoGAP-p50rhoGAP 238..432 CDD:239869 71/200 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1511935at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.920

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