Protein Alignment RhoGAP92B and arhgap8

DIOPT Version :9

• Sequence 1: NP_001287417.1
• Gene: RhoGAP92B / 42371
• FlyBaseID: FBgn0038747
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001016951.1
• Gene: arhgap8 / 549705
• XenbaseID: XB-GENE-6455435
• Length: 420
• Species: Xenopus tropicalis
• Alignment Length: 500
• Identity: 125/500 - (25%)
• Similarity: 195/500 - (39%)
• Gaps: 152/500 - (30%)

  Fly    22 DSKDSE-LEAIERQVDRYRDTIEKIVRKL--PALSGGGGSGSGSSEEQDKRTKKNSHYKIAQALD 83
            ||.|.| |..||.|.|      |:.:..|  |.:|||               :|.|...|.....
 Frog     2 DSVDFEKLAEIELQKD------EEDLEYLGPPVVSGG---------------RKPSDVCIGHPYY 45

  Fly    84 ESAKE-----LPKDMPLQKV-------LANCGELEKTMAECIIESELETEAKVVRRLKNILDKEI 136
            :.|:.     :..|...:||       |..|.|::              ..::::.:|:.||:.:
 Frog    46 DIARHGILHVVGDDNSGRKVITFSCCRLPPCHEID--------------HVRLLQYMKHTLDQYV 96

  Fly   137 QEISTLKRNVSRTLQEYTSLKRSHEAAIRLEEPAAKVNHIKSQQEECELKLEKERDA-------- 193
            :             .:|| |...|.......:|:  :..::|..:|.:.|.:|...|
 Frog    97 E-------------NDYT-LVYFHYGLNSRNKPS--LGWLQSAYKEFDRKYKKNLKALYVVHPTN 145

  Fly   194 -----WAAQMLELIAKEDEIVSCIRDYVLNQRNYH---------ERALQHVNASLARIQDTIQGT 244
                 |......:..|..:.|..::|  ||:.:.|         ...|||.....|.     :|.
 Frog   146 FIKVLWNIFKPIISHKFGKKVLYMKD--LNELHEHLKFNRLIIPPEVLQHDEKLRAH-----KGK 203

  Fly   245 EKS-------------RFGTSLKEHLTSTN----------REISYIVELCCCCLLEHGLEEEGLL 286
            ..|             :||.:| :::.:.|          :.|||        |.:.||..|||.
 Frog   204 PSSAKSPPPRPPLPTQQFGVTL-QYIRNKNNGDLIPPVMVQTISY--------LKQKGLRTEGLF 259

  Fly   287 RVGCASTKLRRMKHALEAQHVKTPLPLD-YQDPHVIGSILKLYLRELPEPLLTYNLY---KDFIR 347
            |   .|..:..:|...:..:|..|:..| |.:.|:...|||.:|||||||||||:.|   :|.|.
 Frog   260 R---RSVSVHILKDVQKLYNVGKPVNFDTYDNIHIPAVILKTFLRELPEPLLTYDSYGPIQDIIG 321

  Fly   348 IAERHSEAERKTEIKAILTKLPKENYANLRYLTRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPR 412
            :    ..:.|.|..:.|:.|||:.|||.|:||..||.:|.|:...|||:|.||..:...|::|.|
 Frog   322 V----ESSLRVTRCRQIVQKLPEHNYAVLKYLLCFLHLVCQQHIHNKMTSSNLGCIFGLNLIWQR 382

  Fly   413 IDKSSNAPADYIGQVNSSSAANIIVELLISQWDYFFI-----GEV 452
                     :.|..:|:....|:..||||..:...|.     |||
 Frog   383 ---------EQIQSLNALVPVNLFAELLIEFYPQIFSPKSVPGEV 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP92B	NP_001287417.1	BAR	27..257	CDD:299863	51/279 (18%)
		RhoGAP_nadrin	245..452	CDD:239851	73/238 (31%)
arhgap8	NP_001016951.1	CRAL_TRIO_2	62..184	CDD:290435	25/153 (16%)
		RhoGAP	218..409	CDD:295372	70/215 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1511935at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010