Protein Alignment RhoGAP92B and Fam13a

DIOPT Version :9

• Sequence 1: NP_001287417.1
• Gene: RhoGAP92B / 42371
• FlyBaseID: FBgn0038747
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001094332.1
• Gene: Fam13a / 362378
• RGDID: 1309807
• Length: 692
• Species: Rattus norvegicus
• Alignment Length: 684
• Identity: 119/684 - (17%)
• Similarity: 226/684 - (33%)
• Gaps: 259/684 - (37%)

  Fly   135 EIQEIST----LKRNVSRTLQEY-----TSLKRSHEAAIRLEEPA-AKVNHIKSQQEECELKLEK 189
            ::..:||    |:|.:...::|:     :|..:|.|.:    ||. :..:...::|...:.|  |
  Rat    29 QVSSVSTTGELLERTIRSAVEEHLFDVNSSADQSSEDS----EPGPSSASSTPTRQRGHQFK--K 87

  Fly   190 ERDAWAAQMLELIAKED---EIVSCIRDYVLNQRNYHERALQHVNASLARIQDTIQGTEKSRFGT 251
            :.|.|..|..|||.||:   .:.|| .:.:||.:                        |..||..
  Rat    88 QDDVWYGQDKELINKENIPCGLSSC-DECILNSQ------------------------EAERFQD 127

  Fly   252 SLKEHL-----TSTNREISYIVELCCCCLLEHGLEEEGLLRVGCASTKLRRMKHALEAQHVKTPL 311
            .:.|::     ....:..|.:.|||
  Rat   128 DICEYVGERSKAKRQKSSSRLAELC---------------------------------------- 152

  Fly   312 PLDYQDPHV-IGSILKLYLRELPEPLLTYNLYKDFIRIAERHSEAERKTEIKAILTKLPKENYAN 375
              :..|.|: ..|:..:..:|..||                  ||   .|:::..:|..:.::.:
  Rat   153 --ENHDGHLSTESLSSMQTQETAEP------------------EA---VELRSSESKEAERSWRD 194

  Fly   376 LRYLTRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPRIDKSSNAPADYI---GQVNSSSAANIIV 437
            .::.......:|:..:::....|             |.....:....::   .|::.::..:...
  Rat   195 TQHCESPAMKIQEHPSISDTKQQ-------------RNQDDDDQQESFVPDLPQLDLTALCDKTW 246

  Fly   438 ELLISQWDYFFIGEVEFYLTLQKQKLFVEGKSKSNSSNENLDRNDSEVMESPR---YGTLRRQKA 499
            |..|..|....:...|..|:.|..:|.          ::.|| .||:.|.|||   ||..|:...
  Rat   247 EEPIPSWQQENVESDEARLSPQAGRLI----------HQLLD-EDSDPMLSPRFYAYGQSRQYLD 300

  Fly   500 NA---PSPPTTNGNGIIMTTSQTSHRPHAKELFPQQ-------------------------TPEK 536
            :.   ||||.::......::|..|:....::|.|.|                         .|..
  Rat   301 DTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPVQLTRRIQTLKKKIRKFEDRFEEERKYRPSH 365

  Fly   537 QEKPAKPPL----PNLPQFQSPAASQPTQTQLEPLPPPPVTPAKPVPMTRTQFFGLDNLPSPTAD 597
            .:|.|.|.:    .:|.:|:    .|..:|:|:      ::.....|.||.:   .:.||.
  Rat   366 SDKAANPEVLKWTNDLAKFR----KQLKETKLK------ISEEDLTPRTRQR---SNTLPK---- 413

  Fly   598 RKSTDSIGSFKLKPDVPQKPLLPK--RPTVLGVGVPKADGKSDDEGGTTPTQATIDNGNGSVRFK 660
                 |.||...|.|..::.|:.|  ||:|                     :||:
  Rat   414 -----SFGSQLEKEDEKKQELVDKAIRPSV---------------------EATL---------- 442

  Fly   661 TEHFLDKLRQENGETNGTREVSSTTKENNHN---------------HDPPATAADQNQQQAQPQV 710
             |..|.||:::..|::...::...||:...|               |..|.|..::       |:
  Rat   443 -EGILRKLQEKRMESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKTER-------QI 499

  Fly   711 TTPISPNSFQTPKR-----PTVPAPPPPTNWKSS 739
            ..|:. :.::..|:     .|||....|::.:.|
  Rat   500 MKPLY-DRYRLVKQILSRASTVPIIGSPSSKRRS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP92B	NP_001287417.1	BAR	27..257	CDD:299863	29/134 (22%)
		RhoGAP_nadrin	245..452	CDD:239851	25/215 (12%)
Fam13a	NP_001094332.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4270
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900