Protein Alignment RhoGAP92B and Arhgap24

DIOPT Version :10

• Sequence 1: NP_650844.1
• Gene: RhoGAP92B / 42371
• FlyBaseID: FBgn0038747
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_038947751.1
• Gene: Arhgap24 / 305156
• RGDID: 1306669
• Length: 785
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 126/537 - (23%)
• Similarity: 226/537 - (42%)
• Gaps: 115/537 - (21%)

  Fly   236 RIQDTIQGTEKSRFGTSLKEHLTSTNREISYIVELCCCCLLEHGLEEEGLLRVGCASTKLRRMKH 300
            :::||::  .:.|:|          ||....:||.|...:.:.||:||||.|:...:..::.::.
  Rat   172 KLEDTVR--YEKRYG----------NRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQD 224

  Fly   301 ALEAQHVKTPLPLDYQDPHVIGSILKLYLRELPEPLLTYNLYKDFIRIAERHSEAERK--TEIKA 363
            |.:..  :.|......|.|.:.|:|||||||||||::.|..|:||:..|...|:.|..  .|:..
  Rat   225 AFDCG--EKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKELTK 287

  Fly   364 ILTKLPKENYANLRYLTRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPRIDKSSNAPADYIGQVN 428
            .:..||..||..|:|:.|||..||..|.:||||:||||.|..||:|.|:::       |.:..:.
  Rat   288 QVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVE-------DPLTIME 345

  Fly   429 SSSAANIIVELLISQWDYFFIGEVEFYLTLQKQKLFVEGKSKSNSSN---------ENLDRNDSE 484
            .:.....::.::||:.|..|..:.|      .|....||.:.:|:..         :|.:.|:::
  Rat   346 GTVVVQQLMSVMISKHDRLFPKDTE------PQSKPQEGPNSNNNDGHKKVTMGQLQNKENNNTK 404

  Fly   485 VMESPRYGTLRRQKANAPSPP----TTNGNGIIMTTSQTSHRPHAKELFPQQTPEKQEKPAKPPL 545
              |||    :||...:.|..|    ..||:...::.|:|:.        |:.:..|.:....|||
  Rat   405 --ESP----VRRCSWDKPESPQRSSMDNGSPTALSGSKTNS--------PRNSIHKLDVSRSPPL 455

  Fly   546 --PNLPQFQSPAA----SQPTQTQLEPLPPPPVTPAKPVPMTRTQFFGLDNLPSPTADRKSTDSI 604
              ...|.|...:.    ...:.:..|.:.....||...:...||     .:|.| :..:..|.|:
  Rat   456 TVKKNPAFNKGSGIVTNGSFSSSNAEGVEKTQTTPNGSLQARRT-----SSLKS-SGTKMGTHSV 514

  Fly   605 GSFKLKPDVPQKPLLPKRPTVLGVGVPKADGKSDDEGGTTPTQATIDNGNGSVRFKTEHFLDKLR 669
            .:..::                 :|:...|...:...|.  :.:.:.||..::|.      :|.:
  Rat   515 QNGTVR-----------------MGILNTDTLGNSLNGR--SMSWLPNGYVTLRD------NKQK 554

  Fly   670 QENGETNGTREVSSTTKENNH------NHDPPATAADQNQQQAQPQVTTPISPNSFQT-----PK 723
            :..||:.....:|  |.:|.|      |.|...:........:..:::.|.:.||.::     |:
  Rat   555 EPAGESGQHNRLS--TYDNVHQQFSLMNLDDKHSVDSATWSTSSCEISLPENSNSCRSSTTTCPE 617

  Fly   724 R---------PTVPAPP 731
            :         |.:..||
  Rat   618 QDFYGGNFEDPVLDGPP 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP92B	NP_650844.1	BAR	27..257	CDD:472257	4/20 (20%)
		RhoGAP_nadrin	245..452	CDD:239851	68/208 (33%)
		PRK13855	495..>650	CDD:172376	27/164 (16%)
Arhgap24	XP_038947751.1	PH_RhoGap24	54..167	CDD:241530
		RhoGAP_ARHGAP22_24_25	167..365	CDD:239855	69/213 (32%)
		ERM_helical	689..>762	CDD:466641