Protein Alignment CG4538 and MCX1

DIOPT Version :9

• Sequence 1: NP_001287413.1
• Gene: CG4538 / 42369
• FlyBaseID: FBgn0038745
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_009786.1
• Gene: MCX1 / 852528
• SGDID: S000000431
• Length: 520
• Species: Saccharomyces cerevisiae
• Alignment Length: 555
• Identity: 183/555 - (32%)
• Similarity: 266/555 - (47%)
• Gaps: 112/555 - (20%)

  Fly   157 VKCAKCNYFFVVLSEVETKQRTKDEPKNQRKPP--PPPQKIMEYLDKHVVGQDFAKKVLAVAVYN 219
            :|.|..|:|....|.:.....|......|.:..  |.|:.:.::||:::|||:..||||:|||||
Yeast     2 LKSASQNFFRAYSSRIGRYAATASGKLAQSRLSNIPTPKALKKFLDEYIVGQEIGKKVLSVAVYN 66

  Fly   220 HYKRIH--HNLPQLQNQGAGASNGAGGGLDGIPRPDLLHITGIGHTLNSSPGNELPPKSPTQMGM 282
            ||.||:  ....:||.|                 .:|:....|      :...:.|..|
Yeast    67 HYLRINDKQKKGELQRQ-----------------RELMEREKI------ADDRDEPIFS------ 102

  Fly   283 GGGMGGPGLGAGLTGASSSNARGGGDNRSGSEILDRQ--------STDVKLEKSNIIMLGPTGSG 339
                                  |..::::|...|.||        ..|::|.|||::::||:|||
Yeast   103 ----------------------GNSESKAGWRNLQRQFNLAGREVDEDLELSKSNVLVVGPSGSG 145

  Fly   340 KTLIAQTIAKCLDVPFAICDCTTLTQAGYVGEDIESVISKLLQDANYNVERAQTGIVFLDEVDKI 404
            |||:|.|:||.|:||.||.|||.||||||:|||:|..|.:||.:|.::|.||:.||:.|||:||:
Yeast   146 KTLLATTLAKILNVPIAITDCTQLTQAGYIGEDVEVCIERLLVNAEFDVARAEKGIIVLDEIDKL 210

  Fly   405 GAVPGIHQLRDVGGEGVQQGMLKMLEGTVVNVP-----------ERNSPRKLRGETVQVDTTNIL 458
            .........:||.||||||.:||::||..|.:.           ::|.....:.|...|||:|||
Yeast   211 AKPAASIGTKDVSGEGVQQSLLKIIEGHKVEITVKRPVKHDIDGQKNQTTTKKDEVFVVDTSNIL 275

  Fly   459 FVASGAYTGLDRLIARRLNEKYLGFGMPSTSGSGRRAAQSAASPMDN------------DQEERD 511
            |:..||:.|||:.|.:|:.:      |.....:|.....|.:..::.            :|.|.|
Yeast   276 FMIMGAFVGLDKHIVKRIED------MKKIQKAGESVESSNSKEVEKERAKKFRFSNTLEQVELD 334

  Fly   512 K-----CLTKVQARDLVEFGMIPEFVGRFPVIVPFHSLNVSMLVRILTEPRNALVPQYKALLGLD 571
            .     .|......|||.||:|||.:||.|:|.....|....|..||.||:|||:.||:.:....
Yeast   335 NGKKVCALDLTTPTDLVSFGLIPELIGRVPIITALQPLQRDDLFHILKEPKNALLDQYEYIFKQF 399

  Fly   572 EVDLTFTEDAVKSIAQLAMERHTGARGLRSIMEQLLLDPMFIVPGSDIRGVHITADYVKGSATPE 636
            .|.|..|:.|:|.:||.|::..|||||||.|||:|||:..:..|||:|..|.|....|......|
Yeast   400 GVRLCVTQKALKKVAQFALKEGTGARGLRGIMERLLLNVNYDCPGSNIAYVLIDEATVDSLQETE 464

  Fly   637 YSRDADAAASGTVATDSDTTTDNDKNFENSEKSGL 671
            :|          :|:..|.     |.:...||..|
Yeast   465 HS----------LASQVDV-----KYYSGDEKDSL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4538	NP_001287413.1	ClpX	140..638	CDD:224140	176/520 (34%)
		AAA_2	327..537	CDD:285025	93/237 (39%)
		ClpB_D2-small	544..631	CDD:198154	39/86 (45%)
MCX1	NP_009786.1	ClpX	1..478	CDD:224140	180/547 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346201
Domainoid	1	1.000	169	1.000	Domainoid score	I786
eggNOG	1	0.900	-	-		E1_COG1219
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4851
Inparanoid	1	1.050	287	1.000	Inparanoid score	I538
Isobase	1	0.950	-	0	Normalized mean entropy	S1175
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002664
OrthoInspector	1	1.000	-	-		oto99297
orthoMCL	1	0.900	-	-		OOG6_101643
Panther	1	1.100	-	-	LDO	PTHR48102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2184
SonicParanoid	1	1.000	-	-		X1775
TreeFam	1	0.960	-	-
	15	14.730