Protein Alignment CG4538 and clpx

DIOPT Version :9

• Sequence 1: NP_001287413.1
• Gene: CG4538 / 42369
• FlyBaseID: FBgn0038745
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_012814634.1
• Gene: clpx / 733875
• XenbaseID: XB-GENE-991453
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 647
• Identity: 350/647 - (54%)
• Similarity: 426/647 - (65%)
• Gaps: 106/647 - (16%)

  Fly    57 CARNRLMRLEPAMAIPAYI---------DVTNAHSRTPEDSSESGSGSEGGASASGGSGAKSPGG 112
            |:|.||..|:...:...|:         .||..:..: :|:.:.||| :|...:.|..|:|...|
 Frog    23 CSRGRLSLLKRQRSSEFYLTWKVPFRRFTVTTVYYAS-KDAGKDGSG-DGNKKSVGDGGSKKSSG 85

  Fly   113 AAGSGASSTSGADPPGGGSDKFLSCPKCGSACTQVETFVSSTRFVKCAKCNYFFVVLSEVETKQR 177
            .:|.|.:.              |.|||||..||.|||||||||||||.||::|||||||.::|:.
 Frog    86 GSGKGGNQ--------------LRCPKCGDLCTHVETFVSSTRFVKCEKCHHFFVVLSEADSKKT 136

  Fly   178 TKDEPKN---------QRKPPPPPQKIMEYLDKHVVGQDFAKKVLAVAVYNHYKRIHHNLPQLQN 233
            ...||:.         |:||||||:||..||||:||||.||||||:||||||||||::|:|....
 Frog   137 MSKEPETAAEAVKLAFQQKPPPPPKKIYNYLDKYVVGQSFAKKVLSVAVYNHYKRIYNNIPTNLR 201

  Fly   234 QGAGASNGAG---GGLDGIPRPD------LLHITGI---GHTLNSSPGNELPPKSPTQMGMGGGM 286
            |.|.....|.   ..|:...|.|      ||.|.||   |:.|.:|...::..:.|.:
 Frog   202 QQAEVEKQASLTPRELEIRRREDEYRFTKLLQIAGISPHGNALGASMQQQVNQQMPQE------- 259

  Fly   287 GGPGLGAGLTGASSSNARGGGDNRSGSEILDRQSTDVKLEKSNIIMLGPTGSGKTLIAQTIAKCL 351
                                   |.|.|:||..:.::|||||||::||||||||||:|||:||||
 Frog   260 -----------------------RRGGEVLDSNNDEIKLEKSNILLLGPTGSGKTLLAQTLAKCL 301

  Fly   352 DVPFAICDCTTLTQAGYVGEDIESVISKLLQDANYNVERAQTGIVFLDEVDKIGAVPGIHQLRDV 416
            ||||||||||||||||||||||||||:|||||||||||:||.||||||||||||:||||||||||
 Frog   302 DVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNVEKAQQGIVFLDEVDKIGSVPGIHQLRDV 366

  Fly   417 GGEGVQQGMLKMLEGTVVNVPERNSPRKLRGETVQVDTTNILFVASGAYTGLDRLIARRLNEKYL 481
            ||||||||:||:||||:|||||:|| ||||||||||||||||||||||:.||||:|:||.|||||
 Frog   367 GGEGVQQGLLKLLEGTIVNVPEKNS-RKLRGETVQVDTTNILFVASGAFNGLDRIISRRKNEKYL 430

  Fly   482 GFGMPSTSGSGRRAAQSA----ASPMDN---DQEERDKCLTKVQARDLVEFGMIPEFVGRFPVIV 539
            |||:.|..|.|||||.:|    ||...|   |.||:|:.|..|:||||:|||||||||||.||:|
 Frog   431 GFGIASNLGKGRRAAAAADLANASSESNVVQDIEEKDRLLRLVEARDLIEFGMIPEFVGRLPVVV 495

  Fly   540 PFHSLNVSMLVRILTEPRNALVPQYKALLGLDEVDLTFTEDAVKSIAQLAMERHTGARGLRSIME 604
            |.|||:...|||||||||||:||||:||..:|:.:|:..|||:::||:||:||.|||||||||||
 Frog   496 PLHSLDEQTLVRILTEPRNAVVPQYQALFSMDKCELSINEDALRAIARLALERKTGARGLRSIME 560

  Fly   605 QLLLDPMFIVPGSDIRGVHITADYVKGSATPEY----------------------SRDADAA 644
            :|||:|||.||.|||..|.:..:.|:|...|.|                      ||.||||
 Frog   561 KLLLEPMFEVPNSDIVCVEVDQEVVEGKKDPRYVKTQRKEVTEEEYDSGVEEEGWSRQADAA 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4538	NP_001287413.1	ClpX	140..638	CDD:224140	321/547 (59%)
		AAA_2	327..537	CDD:285025	172/216 (80%)
		ClpB_D2-small	544..631	CDD:198154	53/86 (62%)
clpx	XP_012814634.1	Zn-ribbon	95..123	CDD:383047	22/27 (81%)
		clpX	163..599	CDD:235422	284/466 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	341	1.000	Domainoid score	I1083
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	613	1.000	Inparanoid score	I895
OMA	1	1.010	-	-		QHG49224
OrthoDB	1	1.010	-	-		D1040247at2759
OrthoFinder	1	1.000	-	-		FOG0002664
OrthoInspector	1	1.000	-	-		oto103056
Panther	1	1.100	-	-	LDO	PTHR48102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2184
SonicParanoid	1	1.000	-	-		X1775
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110