Protein Alignment CG4538 and clpxa

DIOPT Version :9

• Sequence 1: NP_001287413.1
• Gene: CG4538 / 42369
• FlyBaseID: FBgn0038745
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_021333146.1
• Gene: clpxa / 447842
• ZFINID: ZDB-GENE-040912-143
• Length: 624
• Species: Danio rerio
• Alignment Length: 665
• Identity: 356/665 - (53%)
• Similarity: 437/665 - (65%)
• Gaps: 86/665 - (12%)

  Fly    29 SARCVILSAGSAENSDCGV--RRFHLATRNCARNRLMRLEPAMAIPAYIDVTNAHSRTPEDSSES 91
            |..|.|.:.....::..|:  .|..|.:.:....|.:||  |..:|.......|.....:|..:.
Zfish     2 SCTCAIAARKFINSAHKGISGSRVQLLSLSRPGTREVRL--ARRVPVRSFSETAVYYASKDGVKD 64

  Fly    92 GSGSEGGASASGGSGAKSPGGAAGSGASSTSGADPPGGGSDKFLSCPKCGSACTQVETFVSSTRF 156
            |.|  |..|...|||.::..|.:|.|.|.              |.|||||..||.||||||||||
Zfish    65 GDG--GKKSVGEGSGKRTSSGNSGKGGSQ--------------LRCPKCGDPCTHVETFVSSTRF 113

  Fly   157 VKCAKCNYFFVVLSEVETKQRTKDEPKN---------QRKPPPPPQKIMEYLDKHVVGQDFAKKV 212
            |||.||::|||||||.:||:....:|::         |:||||||:||..||||:|||||.||||
Zfish   114 VKCEKCHHFFVVLSETDTKKSLSKDPESAAEAVKLAFQQKPPPPPKKIFAYLDKYVVGQDHAKKV 178

  Fly   213 LAVAVYNHYKRIHHNLP----QLQNQGAGASNGAGGGLDGIPRPD------LLHITGI---GHTL 264
            |:||||||||||::|:|    |.|.:....::.....|:...|.|      ||.|.||   |:.|
Zfish   179 LSVAVYNHYKRIYNNMPAGSRQQQVEVEKQASLTPRELELRRREDEYRFTKLLQIAGISPHGNAL 243

  Fly   265 NSSPGNELPPKSPTQMGMGGGMGGPGLGAGLTGASSSNARGGGDNRSGSEILDRQSTDVKLEKSN 329
            .:|...:|..::|.:                              :.|.|:||...||:||||||
Zfish   244 GASMQQQLNQQTPPE------------------------------KRGGEVLDSTHTDIKLEKSN 278

  Fly   330 IIMLGPTGSGKTLIAQTIAKCLDVPFAICDCTTLTQAGYVGEDIESVISKLLQDANYNVERAQTG 394
            |::||||||||||:|||:||||||||||||||||||||||||||||||:||||||||.:|:||.|
Zfish   279 IVLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYVIEKAQQG 343

  Fly   395 IVFLDEVDKIGAVPGIHQLRDVGGEGVQQGMLKMLEGTVVNVPERNSPRKLRGETVQVDTTNILF 459
            |||||||||||:||||||||||||||||||:||:||||:|||||:|: |||||||||||||||||
Zfish   344 IVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNT-RKLRGETVQVDTTNILF 407

  Fly   460 VASGAYTGLDRLIARRLNEKYLGFGMPSTSGSGRRAAQSAASPMDN----------DQEERDKCL 514
            |||||:.||||:|:||.||||||||.||..|.|||||  ||:.:.|          :.||:|:.|
Zfish   408 VASGAFNGLDRIISRRKNEKYLGFGTPSNMGKGRRAA--AAADLANTTGGEVDAVAEIEEKDRLL 470

  Fly   515 TKVQARDLVEFGMIPEFVGRFPVIVPFHSLNVSMLVRILTEPRNALVPQYKALLGLDEVDLTFTE 579
            ..|:||||:|||||||||||.||:||.|||:...|||||||||||:||||:||..:|:.:|..|.
Zfish   471 KHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEETLVRILTEPRNAVVPQYQALFSMDKCELNMTP 535

  Fly   580 DAVKSIAQLAMERHTGARGLRSIMEQLLLDPMFIVPGSDIRGVHITADYVKGSATPEYSRDADAA 644
            ||:::||:||:||.|||||||||||:|||||||.||.|||..|.::.|.|:|.|.|:|.| |.|.
Zfish   536 DALRAIARLALERKTGARGLRSIMEKLLLDPMFEVPHSDIVSVDVSKDVVQGKAPPQYIR-AAAK 599

  Fly   645 ASGTVATDSDTTTDN 659
            .|.....||....:|
Zfish   600 ESSEEEYDSGIEEEN 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4538	NP_001287413.1	ClpX	140..638	CDD:224140	320/529 (60%)
		AAA_2	327..537	CDD:285025	168/219 (77%)
		ClpB_D2-small	544..631	CDD:198154	55/86 (64%)
clpxa	XP_021333146.1	Zn-ribbon	93..121	CDD:322013	22/27 (81%)
		clpX	161..599	CDD:235422	286/471 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594997
Domainoid	1	1.000	339	1.000	Domainoid score	I1068
eggNOG	1	0.900	-	-		E1_COG1219
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4851
Inparanoid	1	1.050	616	1.000	Inparanoid score	I867
OMA	1	1.010	-	-		QHG49224
OrthoDB	1	1.010	-	-		D1040247at2759
OrthoFinder	1	1.000	-	-		FOG0002664
OrthoInspector	1	1.000	-	-		otm25380
orthoMCL	1	0.900	-	-		OOG6_101643
Panther	1	1.100	-	-	O	PTHR48102
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1775
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770