Protein Alignment CG4538 and D2030.2

DIOPT Version :9

• Sequence 1: NP_001287413.1
• Gene: CG4538 / 42369
• FlyBaseID: FBgn0038745
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_001021076.1
• Gene: D2030.2 / 172511
• WormBaseID: WBGene00008412
• Length: 586
• Species: Caenorhabditis elegans
• Alignment Length: 588
• Identity: 245/588 - (41%)
• Similarity: 331/588 - (56%)
• Gaps: 93/588 - (15%)

  Fly    88 SSESGSGSEGGASASGGSGAKSPGGAAGSGASSTSGADPPGGGSDKFLSCPKCGSACTQVETFVS 152
            ||.|.||.:.|  ..||:..::.||...:.        ||......|..|..|......:.|...
 Worm    36 SSSSSSGGDNG--NDGGNNGENGGGDLTNA--------PPNKAVQSFGQCRHCSKPLKPLPTLTP 90

  Fly   153 STRFVKCAKC------NYFFVVLSEVETKQRTKDEPKN-------QRKPPPPPQKIMEYLDKHVV 204
            |.|::.|..|      |||             :|..||       .||.||.|.:|.|||||.||
 Worm    91 SNRYIHCDSCNKLYFANYF-------------EDSAKNGMFSKQFARKTPPYPTQIAEYLDKFVV 142

  Fly   205 GQDFAKKVLAVAVYNHYKRIHHNL-----------PQLQNQGAGASNGAGGGLD-----GIPRPD 253
            ||..|||.|||.||.||:|:.||:           .|..:.|...||   .|:|     |:...|
 Worm   143 GQKKAKKTLAVGVYQHYRRLEHNIETGASSIYQTHAQTSSSGKSLSN---DGMDPKMPRGVFYQD 204

  Fly   254 LLHI-----TGIGHTLNSSPGNELPPKSPTQMGMGGGMGGPGLGAGLTGASSSNARGGGDNRSGS 313
            .|.:     :.:.:::.....|..|| ||.|                   |..||      ....
 Worm   205 ELRLGQMASSELRNSIMQQQSNNQPP-SPAQ-------------------SPRNA------APTF 243

  Fly   314 EILDRQSTDVKLEKSNIIMLGPTGSGKTLIAQTIAKCLDVPFAICDCTTLTQAGYVGEDIESVIS 378
            ..|..:...|:|||||::::||:|.|||.:.||:|:.||||.|:||||::|||||||||:||||.
 Worm   244 RALPEKEQSVRLEKSNVLLVGPSGVGKTFLTQTLARVLDVPIALCDCTSMTQAGYVGEDVESVIQ 308

  Fly   379 KLLQDANYNVERAQTGIVFLDEVDKIGAVPGIHQ--LRDVGGEGVQQGMLKMLEGTVVNVPERNS 441
            ||:|.|..|||:||.|||||||||||.|....|.  .|||.|||||..:||::|||||||.....
 Worm   309 KLVQAAGGNVEKAQQGIVFLDEVDKIAAAHEGHSAAYRDVSGEGVQHALLKLVEGTVVNVKSGKK 373

  Fly   442 PRKLRGETVQVDTTNILFVASGAYTGLDRLIARRLNEKYLGFGMPSTSGSGRRAAQSAASPMDND 506
            ....:.:.||:|||:|||:||||::.||:::.|||::|.||||  ::||:.|.:...:.|.:
 Worm   374 GMGSQQDQVQIDTTDILFIASGAFSNLDKIVGRRLDKKALGFG--TSSGNVRISGDDSNSEV--- 433

  Fly   507 QEERDKCLTKVQARDLVEFGMIPEFVGRFPVIVPFHSLNVSMLVRILTEPRNALVPQYKALLGLD 571
            ..:||:.|:|....||:.|||:||.||||||:|||||.:..||||::|||:|:|:.|.|...|:|
 Worm   434 MRKRDELLSKADQGDLISFGMVPELVGRFPVLVPFHSFDKQMLVRVMTEPQNSLLAQLKLQFGID 498

  Fly   572 EVDLTFTEDAVKSIAQLAMERHTGARGLRSIMEQLLLDPMFIVPGSDIRGVHITADYVKGSATPE 636
            .|||:|:.:|::.:||||::|.||||.||||:|..||:..|.||||||..||::.:.:.|....|
 Worm   499 NVDLSFSAEALEQVAQLALDRKTGARALRSILEAALLEAKFTVPGSDIESVHVSREAILGEKEVE 563

  Fly   637 YSR 639
            |||
 Worm   564 YSR 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4538	NP_001287413.1	ClpX	140..638	CDD:224140	228/533 (43%)
		AAA_2	327..537	CDD:285025	114/211 (54%)
		ClpB_D2-small	544..631	CDD:198154	43/86 (50%)
D2030.2	NP_001021076.1	clpX	94..570	CDD:235422	227/520 (44%)
		AAA_2	257..464	CDD:285025	114/211 (54%)
		ClpB_D2-small	472..555	CDD:198154	43/82 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166564
Domainoid	1	1.000	228	1.000	Domainoid score	I1416
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4851
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1059
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49224
OrthoDB	1	1.010	-	-		D1040247at2759
OrthoFinder	1	1.000	-	-		FOG0002664
OrthoInspector	1	1.000	-	-		oto17811
orthoMCL	1	0.900	-	-		OOG6_101643
Panther	1	1.100	-	-	LDO	PTHR48102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2184
SonicParanoid	1	1.000	-	-		X1775
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940