Protein Alignment CG4538 and clpxb

DIOPT Version :9

• Sequence 1: NP_001287413.1
• Gene: CG4538 / 42369
• FlyBaseID: FBgn0038745
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_002667004.2
• Gene: clpxb / 100332309
• ZFINID: ZDB-GENE-130404-1
• Length: 618
• Species: Danio rerio
• Alignment Length: 619
• Identity: 348/619 - (56%)
• Similarity: 425/619 - (68%)
• Gaps: 76/619 - (12%)

  Fly    49 RFHLATRNCARNRLMRLEPAMAIPAY---IDVTNAHSRTPEDSSESGSGSEGGASASGGSGAKSP 110
            |.|:.:|:.:....:.|.|.:.:..:   :...::....|.|       .:||..|.|.|| |..
Zfish    24 RVHVFSRSRSACDELHLPPVLNVRCFSQSVVCFSSKESPPRD-------GDGGKKAVGESG-KRA 80

  Fly   111 GGAAGSGASSTSGADPPGGGSDKFLSCPKCGSACTQVETFVSSTRFVKCAKCNYFFVVLSEVETK 175
            .||.|||.          |||.  |.|||||..||.|||||||||||||.||::|||||||.::|
Zfish    81 SGAGGSGK----------GGSQ--LRCPKCGDPCTHVETFVSSTRFVKCEKCHHFFVVLSETDSK 133

  Fly   176 QRTKDEPKNQ--------RKPPPPPQKIMEYLDKHVVGQDFAKKVLAVAVYNHYKRIHHNLPQLQ 232
            :....|.::.        :||||||:||..||||.||||.:|||||:||||||||||::|||...
Zfish   134 KGLNKETESSEHVKFALAQKPPPPPKKIYAYLDKFVVGQSYAKKVLSVAVYNHYKRIYNNLPAAG 198

  Fly   233 NQGAGA---SNGAGGGLDGIPRPD------LLHITGIGHTLNSSPGNELPPKSPTQMGMGGGMGG 288
            .|.|.:   |:.:...|:...|.|      ||.|.||               ||         .|
Zfish   199 RQQAESEKQSSLSPRELEIRRREDEYRFTKLLQIAGI---------------SP---------HG 239

  Fly   289 PGLGAGLTGASSSNARGGGDNRSGSEILDRQSTDVKLEKSNIIMLGPTGSGKTLIAQTIAKCLDV 353
            ..|||.:...::..|:   .::.|.::||...||:|||||||::||||||||||:|||:||||||
Zfish   240 NALGASVQQQTNQQAQ---QDKRGGDVLDSAHTDIKLEKSNIVLLGPTGSGKTLLAQTLAKCLDV 301

  Fly   354 PFAICDCTTLTQAGYVGEDIESVISKLLQDANYNVERAQTGIVFLDEVDKIGAVPGIHQLRDVGG 418
            ||||||||||||||||||||||||:||||||||:||:||.||||||||||||:||||||||||||
Zfish   302 PFAICDCTTLTQAGYVGEDIESVIAKLLQDANYSVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGG 366

  Fly   419 EGVQQGMLKMLEGTVVNVPERNSPRKLRGETVQVDTTNILFVASGAYTGLDRLIARRLNEKYLGF 483
            ||||||:||:||||:|||||:|| ||||||||||||||||||||||:.||||:|:||.|||||||
Zfish   367 EGVQQGLLKLLEGTIVNVPEKNS-RKLRGETVQVDTTNILFVASGAFNGLDRIISRRKNEKYLGF 430

  Fly   484 GMPSTSGSGRRAAQSA------ASPMD--NDQEERDKCLTKVQARDLVEFGMIPEFVGRFPVIVP 540
            |.||..|.|||||.:|      .:.||  .:.||:|:.|..|:||||:|||||||||||.||:||
Zfish   431 GTPSNLGKGRRAAAAADLANTSGTEMDAMAEIEEKDRLLRIVEARDLIEFGMIPEFVGRLPVVVP 495

  Fly   541 FHSLNVSMLVRILTEPRNALVPQYKALLGLDEVDLTFTEDAVKSIAQLAMERHTGARGLRSIMEQ 605
            .|||:..|||:||||||||:||||:||..:|:.:|..|.||:::||:||:||.|||||||||||:
Zfish   496 LHSLDEEMLVQILTEPRNAVVPQYQALFSMDKCELNVTSDALRAIARLALERKTGARGLRSIMEK 560

  Fly   606 LLLDPMFIVPGSDIRGVHITADYVKGSATPEYSR 639
            |||:|||.||.|||..|.:..|.|:|...|.|.|
Zfish   561 LLLEPMFEVPQSDIIAVELNKDVVQGKCEPRYIR 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4538	NP_001287413.1	ClpX	140..638	CDD:224140	320/522 (61%)
		AAA_2	327..537	CDD:285025	170/217 (78%)
		ClpB_D2-small	544..631	CDD:198154	54/86 (63%)
clpxb	XP_002667004.2	clpX	92..593	CDD:273047	324/530 (61%)
		AAA_2	275..492	CDD:285025	170/217 (78%)
		ClpB_D2-small	499..>570	CDD:198154	46/70 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594996
Domainoid	1	1.000	339	1.000	Domainoid score	I1068
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	616	1.000	Inparanoid score	I867
OMA	1	1.010	-	-		QHG49224
OrthoDB	1	1.010	-	-		D1040247at2759
OrthoFinder	1	1.000	-	-		FOG0002664
OrthoInspector	1	1.000	-	-		otm25380
orthoMCL	1	0.900	-	-		OOG6_101643
Panther	1	1.100	-	-	LDO	PTHR48102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2184
SonicParanoid	1	1.000	-	-		X1775
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940