DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4733 and AT1G54450

DIOPT Version :9

Sequence 1:	NP_001247197.1	Gene:	CG4733 / 42368	FlyBaseID:	FBgn0038744	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_175847.1	Gene:	AT1G54450 / 841887	AraportID:	AT1G54450	Length:	535	Species:	Arabidopsis thaliana

Alignment Length:	444	Identity:	182/444 - (40%)
Similarity:	270/444 - (60%)	Gaps:	20/444 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   454 PQTDPPPKSLMKVKLHATPPPPPQEQNLLQKEIRSTKSV-------YIPRFYFPHGKPQPNIAME 511
            |..:.||.|    ..::|..|....|......:.|...|       .||:|||..|:|.||...|
plant    82 PARNGPPLS----PRNSTGSPRIARQRTGLSNLSSPLKVVSDHVKELIPQFYFEDGRPPPNDLKE 142

  Fly   512 RVVRGILSAFDSFPNNQVTKDELPRILKICGLPFYWRMPVMVFCQSASTGLVERQRFVEFWKQMN 576
            :.:..|.|.|....:....::......:||.:|.::...:.....:.:||.|:|:.|:::|.:.|
plant   143 QCIAKINSLFYGHEDGLQLQEFKLVTTEICKVPSFFSTSIFKKVDTNNTGFVKREDFIDYWVKGN 207

  Fly   577 VYCHEAASRFVYILSRGQRFRSYIVPEDLVPMVQDVVDTHPGLAFLKEATEFHSRYVHTVIARIF 641
            :...|..|:...||.  |...:|:|.:|..|::|:::.|||||.||:...||..||..|||.||:
plant   208 MLTKEITSQVFTILK--QPDHNYLVQDDFKPVLQELLATHPGLEFLQGTPEFQDRYAETVIYRIY 270

  Fly   642 YSVNRSWSGKITIAELKRSDLLEMISLLEEEEDINQIMAFFSYEHFYVIYCKFWELDKDHDLLIN 706
            |.:|||.:|.:|:.||||.:|::.:...:||||||:::.:|||||||||||||||||.|||.||:
plant   271 YYINRSGNGHLTLRELKRGNLVDAMQHADEEEDINKVLRYFSYEHFYVIYCKFWELDTDHDFLID 335

  Fly   707 QEDLAKHSDHALSSRIVERIFSGCVTRSDNKKAPEDEAKMSYTDFVWFILSEEDKRTPTAIEYWF 771
            :|:|.::|:|||:.|||:||||    :...|...:.|.||.|.|||:|||:||||.:..::||||
plant   336 KENLIRYSNHALTYRIVDRIFS----QVPRKFTSKTEGKMGYEDFVYFILAEEDKSSEPSLEYWF 396

  Fly   772 RCMDVDGDGVLSMYELEYFYEEQQQRMEGIGIECLPFEDCLCQMLDMIKPANRDCITLGDLKRCK 836
            :|:|:|.:|||:..||::|||||..|||.:..|.:.|||.|||:.||:||.:...|.|.|||..|
plant   397 KCIDLDANGVLTRNELQFFYEEQLHRMECMAQEAVLFEDILCQLFDMVKPEDEGFICLNDLKGSK 461

  Fly   837 MTHVFFDTFFNLEKYLDHEQRDPFASQRDEYT---SDWDRFAAQEYELLISEEN 887
            ::...|:..|||.|::..|.||||..:::...   ::|||||.:||..|..||:
plant   462 LSGNVFNILFNLNKFMAFETRDPFLIRQERANPTWTEWDRFAHREYIRLSMEED 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4733	NP_001247197.1	EF-hand_7	690..791	CDD:290234	54/100 (54%)
AT1G54450	NP_175847.1	PPP2R3A_B-like	203..476	CDD:410337	136/278 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	129	1.000	Domainoid score	I1713
eggNOG	1	0.900	-	-		E1_KOG2562
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	333	1.000	Inparanoid score	I672
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001858
OrthoInspector	1	1.000	-	-		otm2992
orthoMCL	1	0.900	-	-		OOG6_101579
Panther	1	1.100	-	-	O	PTHR14095
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1783
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.820