DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4733 and AT1G03960

DIOPT Version :9

Sequence 1:	NP_001247197.1	Gene:	CG4733 / 42368	FlyBaseID:	FBgn0038744	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_171892.2	Gene:	AT1G03960 / 839361	AraportID:	AT1G03960	Length:	529	Species:	Arabidopsis thaliana

Alignment Length:	449	Identity:	182/449 - (40%)
Similarity:	270/449 - (60%)	Gaps:	30/449 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   461 KSLMKVKLHATPPP------------------PPQEQNLLQKEIRSTKSVYIPRFYFPHGKPQPN 507
            |:|..|.|.::.||                  ||...:.| :.::..|...||:||:.||:|...
plant    69 KNLPSVFLSSSTPPLSPRSSSGSPRFSRQRTSPPSLHSPL-RSLKEPKRQLIPQFYYQHGRPPAK 132

  Fly   508 IAMERVVRGILSAFDSFPNNQVTKDELPRILK-ICGLPFYWRMPVMVFCQSASTGLVERQRFVEF 571
            ...|:.:..:...|.::.:. :..||...|.| :|.||.:....:........|.:|.|..|:::
plant   133 ELKEQCLSMVDQVFSNYIDG-LHVDEFKSITKQVCKLPSFLSPALFRKIDPNCTDIVTRDAFIKY 196

  Fly   572 WKQMNVYCHEAASRFVYILSRGQRFRSYIVPEDLVPMVQDVVDTHPGLAFLKEATEFHSRYVHTV 636
            |...|:...:.||:...||.  |:..||:...|..|::.:::.|||||.||:..:||..||..||
plant   197 WIDGNMLTMDTASQIYNILR--QQGCSYLRQADFKPVLDELLATHPGLEFLRTISEFQERYAETV 259

  Fly   637 IARIFYSVNRSWSGKITIAELKRSDLLEMISLLEEEEDINQIMAFFSYEHFYVIYCKFWELDKDH 701
            |.||||.:|||.:|.:|:.||:|.:|:..:..|:||:|||:|:.:|||||||||||||||||.||
plant   260 IYRIFYYINRSGTGCLTLRELRRGNLIAAMQQLDEEDDINKIIRYFSYEHFYVIYCKFWELDGDH 324

  Fly   702 DLLINQEDLAKHSDHALSSRIVERIFSGCVTRSDNKKAPEDEAKMSYTDFVWFILSEEDKRTPTA 766
            |..|::::|.|:.::||:.|||:||||. :.|....|.   |.||||.|||:|||:||||.:..:
plant   325 DCFIDKDNLIKYGNNALTYRIVDRIFSQ-IPRKFTSKV---EGKMSYEDFVYFILAEEDKSSEPS 385

  Fly   767 IEYWFRCMDVDGDGVLSMYELEYFYEEQQQRMEGIGIECLPFEDCLCQMLDMIKPANRDCITLGD 831
            :||||:|:|:||:||::..|:::|:|||..|||.|..|.:.|.|.|||::|||.|...:||||.|
plant   386 LEYWFKCVDLDGNGVITSNEMQFFFEEQLHRMECITQEAVLFSDILCQIIDMIGPEKENCITLQD 450

  Fly   832 LKRCKMTHVFFDTFFNLEKYLDHEQRDPF---ASQRDEYTSDWDRFAAQEYELLISEEN 887
            ||..|::...|:..|||.|::..|.||||   ..:.|...::|||||.:||..|..||:
plant   451 LKGSKLSANVFNILFNLNKFMAFETRDPFLIRQEREDPNLTEWDRFAQREYARLSMEED 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4733	NP_001247197.1	EF-hand_7	690..791	CDD:290234	52/100 (52%)
AT1G03960	NP_171892.2	EF-hand_13	206..295	CDD:375447	37/90 (41%)
AT1G03960	NP_171892.2	EF-hand_7	310..410	CDD:372618	55/103 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	129	1.000	Domainoid score	I1713
eggNOG	1	0.900	-	-		E1_KOG2562
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H61474
Inparanoid	1	1.050	333	1.000	Inparanoid score	I672
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001858
OrthoInspector	1	1.000	-	-		otm2992
orthoMCL	1	0.900	-	-		OOG6_101579
Panther	1	1.100	-	-	O	PTHR14095
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1783
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.820