Protein Alignment CG4733 and ppp2r3a

DIOPT Version :9

• Sequence 1: NP_001247197.1
• Gene: CG4733 / 42368
• FlyBaseID: FBgn0038744
• Length: 888
• Species: Drosophila melanogaster
• Sequence 2: XP_009296831.1
• Gene: ppp2r3a / 565849
• ZFINID: ZDB-GENE-070912-646
• Length: 1192
• Species: Danio rerio
• Alignment Length: 1049
• Identity: 342/1049 - (32%)
• Similarity: 484/1049 - (46%)
• Gaps: 271/1049 - (25%)

  Fly     4 NSSTTTTTTT---TKTKKLSSGTGTNMISSVAV-----------TSAIKTTTTTRKPAGSG---- 50
            ||.|.....|   .|||..||.:|.::.:.:.:           |..||.....:...|:.
Zfish   209 NSLTEENLITRILEKTKADSSASGEDIKACLDILLKCSEDLKKCTDIIKQCIKRKSMGGTSDDSG 273

  Fly    51 ------------VSSKVSKAQGATNSTPASSDSNAEIAELTKKIND-----------------HA 86
                        :|:.:.:.........:....::|:|||...|:.                 :.
Zfish   274 NPEIIYKNVMARLSNYLKRLPLELEQGQSIRQEHSELAELVNSIHGLQQIPFSPIFGNEQPPRYE 338

  Fly    87 DAIYHTWKSQGIPPTELLTMYTS---AAASGDLADVASPTADAEGLQKMVTSFVNKDKEQRGKSN 148
            |.:      |..|||:.....:.   :..|.:|.....|.....||........|      |.|
Zfish   339 DVV------QSPPPTKPRNKPSQPEPSEGSRELTGSLKPIQSVPGLSARTPPSTN------GFS- 390

  Fly   149 TLKKSDITTANGKVKKAAVSSFSPVPDQALQSPKKVAAVTVSKPLPDVNLNYDISLDLDVNNLSS 213
                      :|.:..|:.||.:|.          :...|||...||...:.:..|.:...||..
Zfish   391 ----------HGSLPTASSSSSTPF----------ICQHTVSTSRPDTFSSANSFLSISNENLCK 435

  Fly   214 QQTQNLLKISELIQQQKDV--------------AATVGKKRQNS--------------------- 243
            ...:.|.    :.::..|:              :..:.:.||.|
Zfish   436 DPMEALY----IEEEDSDIGRMPDRPVKGDGKHSCNLSESRQYSKRTTGYSEPSGGVSDKLHELS 496

  Fly   244 ------KANSSSSINSNHIGNSASSNKLTASEQPTKKQ--------------------------- 275
                  |..:.|::|..::..|..|...:.|...|.|.
Zfish   497 RNGTTFKPQNDSTVNQMYLPKSTDSKLFSRSTSHTSKGGADDIDKLLMDLECLSQNMQKEPPLPP 561

  Fly   276 -----SKANSSGSTRTGSAAV-SLDVV--DGPSAA-------------------RIANSTAVSDK 313
                 :...||.....|::.| .|.||  .|||.|                   ||..|  :...
Zfish   562 KLKNCALQTSSPQHLIGNSVVKDLPVVGFSGPSVAKPPEPGVESTEEDDGALLLRILES--IESF 624

  Fly   314 GGEPAATGSRKSSKTKETSADSKPATKEKPTAVATVANARKSTSRIATDN-AGNMAAATAAAAAT 377
            ..|...:|:.:.::|||                       :...|:..:. |...|..|......
Zfish   625 AQELVESGAGRGTQTKE-----------------------REVMRLLQETLASTKAEVTPLPLPE 666

  Fly   378 SATSAATATSMDATPATAASTTMPTLNKVKPTSGARAALANGQDKMNLLTRGSVAERVLMFEKCP 442
            |.|:.:...:....||:..|.| ||..:: |.|             .|...||    .|:.::.|
Zfish   667 SETAPSPPQTPQCKPASTLSNT-PTAIQI-PAS-------------TLRDTGS----TLLIQQTP 712

  Fly   443 DVRHAFLNI---KRPQTDPP------------PKSLMKVKLHATPPPPPQEQNLLQKEIRSTKSV 492
            :|    :.|   |:|.|.||            |.|....|:.|||||               .|:
Zfish   713 EV----IRIQPEKKPGTPPPTLSPAPSSPTPRPPSPPPAKVVATPPP---------------SSI 758

  Fly   493 YIPRFYFPHGKPQPNIAMERVVRGILSAFDSFPNNQVTKDELPRILKICGLPFYWRMPVMVFCQS 557
            .|||||||.|.|......:..:..|.:||..|...:....|:.:|.|.||.|.||:.|:.:....
Zfish   759 NIPRFYFPKGLPNCAANYDEAIAKIEAAFTEFEEEKADIYEMGKIAKACGCPLYWKSPMFICAGG 823

  Fly   558 ASTGLVERQRFVEFWKQMNVYCHEAASRFVYILSRGQRFRSYIVPEDLVPMVQDVVDTHPGLAFL 622
            ..||.|....|:..|:::...|::.||:|||:|::..  .:|:..||.:|::||:|||||||.||
Zfish   824 ERTGFVSVHSFIATWRKLLHSCYDDASKFVYLLAKPG--CTYLEQEDFIPLLQDIVDTHPGLTFL 886

  Fly   623 KEATEFHSRYVHTVIARIFYSVNRSWSGKITIAELKRSDLLEMISLLEEEEDINQIMAFFSYEHF 687
            |:|.||||||:.|||.||||:|||||:|||.:.||:||:.|:.::|||||:|||||..:||||||
Zfish   887 KDAPEFHSRYITTVIQRIFYTVNRSWTGKINMTELRRSNFLQTLALLEEEDDINQITDYFSYEHF 951

  Fly   688 YVIYCKFWELDKDHDLLINQEDLAKHSDHALSSRIVERIFSGCVTRSDNKKAPEDEAKMSYTDFV 752
            |||||||||||.||||.|:.:|||:::|||.||||:||:|||.|||.:   :.:.|.:|||.:||
Zfish   952 YVIYCKFWELDSDHDLFIDPKDLARYNDHASSSRIIERLFSGAVTRGN---SVQREGRMSYAEFV 1013

  Fly   753 WFILSEEDKRTPTAIEYWFRCMDVDGDGVLSMYELEYFYEEQQQRMEGIGIECLPFEDCLCQMLD 817
            ||::|||||:.||:|||||||||:||||||||:||||.||||.:||||:|||.|||:|.||||||
Zfish  1014 WFLISEEDKKNPTSIEYWFRCMDMDGDGVLSMFELEYLYEEQCERMEGMGIEPLPFQDLLCQMLD 1078

  Fly   818 MIKPANRDCITLGDLKRCKMTHVFFDTFFNLEKYLDHEQRDPFASQRD-----EYTSDWDRFAAQ 877
            ::||.....|||.|||||:|.|:|:|||||||||||||||||||.|:|     ...||||::|::
Zfish  1079 LVKPECPSKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDLDSDGPEPSDWDKYASE 1143

  Fly   878 EYELLISEE 886
            |||:|::||
Zfish  1144 EYEILVAEE 1152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4733	NP_001247197.1	EF-hand_7	690..791	CDD:290234	68/100 (68%)
ppp2r3a	XP_009296831.1	EF-hand_7	954..1052	CDD:290234	68/100 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I3866
eggNOG	1	0.900	-	-		E1_KOG2562
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001858
OrthoInspector	1	1.000	-	-		otm25758
orthoMCL	1	0.900	-	-		OOG6_101579
Panther	1	1.100	-	-	O	PTHR14095
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5283
SonicParanoid	1	1.000	-	-		X1783
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.800