Protein Alignment CG4733 and Ppp2r3a

DIOPT Version :10

• Sequence 1: NP_650842.2
• Gene: CG4733 / 42368
• FlyBaseID: FBgn0038744
• Length: 888
• Species: Drosophila melanogaster
• Sequence 2: NP_001154834.1
• Gene: Ppp2r3a / 235542
• MGIID: 2442104
• Length: 1150
• Species: Mus musculus
• Alignment Length: 991
• Identity: 341/991 - (34%)
• Similarity: 484/991 - (48%)
• Gaps: 225/991 - (22%)

  Fly    15 KTKKLSSGTGTNMISSVAV---------TSAIKTTTTTRKPAGSGVSSKVSKAQGATNSTPASSD 70
            |....||||...|...:.:         |..||  ...:|.:|..:|      :|:.|...::|:
Mouse   218 KIDHFSSGTDIKMCLDILLKCSEDLKKCTDIIK--QCIKKKSGGSIS------EGSGNEVISNSE 274

  Fly    71 S------------------------NAEIAELTKKINDHAD-------AIYHTWKSQGIPPTELL 104
            :                        |.|..:||:.||:..:       .:|.|.:    ||....
Mouse   275 TVYMNVMTRLAYYLRKLPFEFMQSGNNETVDLTELINNIPNLQLTPFSPLYGTEQ----PPKYED 335

  Fly   105 TMYTSAAASGDLADVASPTADAEGLQKMVTSFVNKDKEQRGKSNTLKKSDI--TTANGKVKKAAV 167
            .::.||..||....|                      |.:...:..|::||  ||.|......::
Mouse   336 IVHLSALDSGQFQTV----------------------ELQDDKHNFKQTDIVKTTPNNTDSLCSL 378

  Fly   168 SSFSPVPDQALQSPKKVAAVTVSKPLPDVNLNYDISLDLDVNNLSSQQTQNLLKISELIQQQKDV 232
            .         :..|..:..|.:..||            |.:|:|.:..:.||:: :..|:::.|
Mouse   379 E---------VNDPGTLKPVQLQSPL------------LTINHLENVSSGNLME-TLYIEEESD- 420

  Fly   233 AATVGK--------KRQNSKANSSSSIN-----SNHIGNSASSNKLTASEQ-------------- 270
                ||        |.:|.:......:|     |:|   .....|...|.|
Mouse   421 ----GKKSLLDKEQKAENGQGQEPLQVNEHKEFSDH---DTYLKKCPVSMQNEIGKIFEKPIMVH 478

  Fly   271 PTKKQSK--------------ANSSGSTRTGSAAVSLDVVDGPSAARIANSTAVSDKGGEPAATG 321
            |:|:.||              .|.:.........:.|:          :.|..:....|||.|.|
Mouse   479 PSKEDSKLEVPTTDLRDQRHFVNPNSQEEIDKLLMDLE----------SFSQKMETSLGEPLAKG 533

  Fly   322 SRKSSKTKETSADSKPATKEKPTAVATVANARKSTS---RIATDNAGNM-------------AAA 370
            ...:|....:...::.....:|..:|:.|..:.|.|   ||..:|...|             :..
Mouse   534 KSINSLNSHSHLTAQSHKDLEPKPIASSAMEKVSPSCLTRIIENNGHKMEEEDRALLLRIMESIE 598

  Fly   371 TAAAAATSATSAATATSMDATPATAASTTMPTLNKVKPTSGARAALANGQDKMNLLTRGSVAER- 434
            ..|.......|...:.|.:.........|:.|.::..|:                :.|..|.|:
Mouse   599 DFAQELVECKSGRGSLSQEKEMMQILQETLTTSSQPTPS----------------VCRSPVGEKP 647

  Fly   435 -----VLMFEKCPDVRHAFLNI-----KRPQTDPPPKSLMKVKLHATPPPPPQEQN---LLQKEI 486
                 |::.::.|:|    :.|     |:|.|..||.        ||.|..||..:   .:...:
Mouse   648 KDSTSVVLIQQTPEV----IKIQNKPEKKPATSFPPA--------ATLPSSPQPASPVPCVSDVV 700

  Fly   487 RSTKSVYIPRFYFPHGKPQPNIAMERVVRGILSAFDSFPNNQVTKDELPRILKICGLPFYWRMPV 551
            .:..|:.||:||||.|.|......|:::..|.:||....:.:....|:.||.|:||.|.||:.|:
Mouse   701 NTPLSINIPQFYFPEGLPDTCSNHEQILSRIETAFKDIEDQKADIHEMGRIAKVCGCPLYWKAPM 765

  Fly   552 MVFCQSASTGLVERQRFVEFWKQMNVYCHEAASRFVYILSRGQRFRSYIVPEDLVPMVQDVVDTH 616
            ........||.|..|.|:..||::....|:.|::|:::|::..  .||:..||.:|::|||||||
Mouse   766 FRAAGGEKTGFVTAQSFIAMWKKLLSNRHDDAAKFIWLLAKPS--CSYLEQEDFIPLLQDVVDTH 828

  Fly   617 PGLAFLKEATEFHSRYVHTVIARIFYSVNRSWSGKITIAELKRSDLLEMISLLEEEEDINQIMAF 681
            |||.|||:|.||||||:.||:.||||:||||||||||..|:::|:.|:.::|||||||||||..:
Mouse   829 PGLTFLKDAPEFHSRYITTVVQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDY 893

  Fly   682 FSYEHFYVIYCKFWELDKDHDLLINQEDLAKHSDHALSSRIVERIFSGCVTRSDNKKAPEDEAKM 746
            |||||||||||||||||.||||.|:|.||::::|.|.|:||:||||||.|||.   |..:.|.:|
Mouse   894 FSYEHFYVIYCKFWELDGDHDLYISQADLSRYNDQASSNRIIERIFSGAVTRG---KTVQKEGRM 955

  Fly   747 SYTDFVWFILSEEDKRTPTAIEYWFRCMDVDGDGVLSMYELEYFYEEQQQRMEGIGIECLPFEDC 811
            ||.|||||::||||||.||:||||||||||||||:|||||||||||||.:|||.:|||.|||.|.
Mouse   956 SYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGILSMYELEYFYEEQCERMEAMGIEPLPFHDL 1020

  Fly   812 LCQMLDMIKPANRDCITLGDLKRCKMTHVFFDTFFNLEKYLDHEQRDPFASQRD-----EYTSDW 871
            ||||||::|||:...|||.|||||:|.|:|:|||||||||||||||||||.|:|     ...|||
Mouse  1021 LCQMLDLVKPASDGRITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDW 1085

  Fly   872 DRFAAQEYELLISEEN 887
            |||||:|||.|::||:
Mouse  1086 DRFAAEEYEALVTEES 1101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4733	NP_650842.2	PPP2R3A_B-like	572..851	CDD:410337	182/278 (65%)
Ppp2r3a	NP_001154834.1	PPP2R3	712..1066	CDD:425382	212/358 (59%)