Protein Alignment CG4733 and F43B10.1

DIOPT Version :10

• Sequence 1: NP_650842.2
• Gene: CG4733 / 42368
• FlyBaseID: FBgn0038744
• Length: 888
• Species: Drosophila melanogaster
• Sequence 2: NP_001335569.1
• Gene: F43B10.1 / 181721
• WormBaseID: WBGene00018373
• Length: 1325
• Species: Caenorhabditis elegans
• Alignment Length: 1018
• Identity: 272/1018 - (26%)
• Similarity: 453/1018 - (44%)
• Gaps: 193/1018 - (18%)

  Fly     4 NSSTTTTTTTTKTKKLSSGTGTNMISSVAVTSAIKTTTTTRKPAGSGVSSKVSKAQG--ATNST- 65
            |.|.:|:..:...::|.: ...|:.|...::.:..|||.:......|....:||:..  ..||:
 Worm   340 NMSRSTSEWSKSFEQLQN-RFQNLESDDLLSPSAFTTTGSMTLPRRGAQLPISKSSSNYEMNSSL 403

  Fly    66 --PASSDSNAEIAELTKKINDHADAIYHTWKS-----------QGIP--------------PTEL 103
              .|.....||..|..|     :.|:.:.|..           |.||              |.:.
 Worm   404 LGRAVERRAAEAPEQRK-----SGALDNFWSQTISSRPSSPTIQRIPTSLTAAERLQMLQEPIDT 463

  Fly   104 LTMYTSAAASGDLADVASPTAD------AEGLQK--------------MVTSFVNKDKEQRGKSN 148
            ...:|....||.  .||:..|:      .|..:|              ::.||...|......|.
 Worm   464 EKRFTQRVGSGQ--GVAARKAELMREPSVEYTEKPRTPLNPAFPSNSFLIPSFNELDNAVNELSR 526

  Fly   149 TLKKSDI-TTANGKVKKAAV--------------------SSFSPVPDQALQSP-----KKVAAV 187
            |::.:.. .|..|.|..|.|                    .:|||.|.:..:||     :|:.:.
 Worm   527 TVRGNTFGGTTFGSVSPAPVVHNDSLNRRVGGCGRFPTGEHAFSPPPIEVSKSPALSLHRKLHSP 591

  Fly   188 TVSKPLPDVNLNYDISLDL----DVNNLSSQQTQNLLKISELIQQQKDVAATVGKKRQNSKANSS 248
            :.:..:.:.:..|.|...|    ..:|:..|     |.::.:......::.|:.:...|....|:
 Worm   592 SPTDEVSESSSVYQIPTGLPHPKPKHNVKEQ-----LHLAGIHTPGYQISRTMYRNGPNFPVPST 651

  Fly   249 SSINSNHIGNSASSNKLTASEQ--------------------PTKKQSKA--NSSGSTRTGSA-- 289
            .|:          ::::|..|:                    |....:||  .::|:....||
 Worm   652 GSV----------ASRITEFEKRPGTPVVQLSTTTVKYNEHVPVAATAKAVPQTNGNMSPRSAVF 706

  Fly   290 -AVSLDVVDGPSAARIANST---------AVSDKGGEPAAT-GSRKSSKTKETSADSKPATKEKP 343
             |..:..||..|..:.::.|         :|.::..:|... .:.:|...||.....:|..:::|
 Worm   707 RAKPVIHVDMGSTYQHSSPTPPIRHIQVHSVQNQNHQPLQNHQNHQSYLGKEQHNHYRPQYQQQP 771

  Fly   344 TAVATVANARKSTSRIATDNAGNMAAATAA--AAATSATSAATATSMDATPATAASTTMP----T 402
            .....:|     |..|....:.|::||:|.  .|..:.|.:|....::.......:.::|    .
 Worm   772 IKQHDIA-----THSIFDFKSNNVSAASATQIQADVTPTKSAHPAELNVVSPPKRTASVPASRLN 831

  Fly   403 LNKVKPTSGARAALANGQDKMNLL--------TRGSVAERVLMFEKCPDVRHAFLNIKRPQTDPP 459
            ||....::|.....:..|..:|..        ||.::.|..|.|:...|.::      ||  .|.
 Worm   832 LNGTLDSNGNYGRKSASQSDLNYSAELSVAAPTRHAIPELDLTFDSYNDEQY------RP--TPK 888

  Fly   460 PKSLMKVKLHATPPPPPQEQNLLQKEIRSTKSVYIPRFYFPHGKPQPNIAMERVVRGILSAFDSF 524
            |..::...|    ||.||    ..||          ..|:|.|||.|.:..:..:|.:...|.|.
 Worm   889 PTQVISRPL----PPKPQ----APKE----------PIYYPQGKPVPQLQNDTALRRVCEVFRSV 935

  Fly   525 PNNQVTKDELPRILKICGLPFYWRMPVMVFCQSASTGLVERQRFVEFWKQMNVYCHEAASRFVYI 589
            ||.:.|.:.:|.:.:..|||.||:|||.:...:....|..:..|..:||.|....|:.|:||||.
 Worm   936 PNQKCTLENMPAVCEAAGLPMYWKMPVFLAITNDEDRLATQVDFTSWWKAMTSVAHDEAARFVYT 1000

  Fly   590 LSRGQRFRSYIVPEDLVPMVQDVVDTHPGLAFLKEATEFHSRYVHTVIARIFYSVNRSWSGKITI 654
            |:.|.  |||:.|||...|:.||:.|||||||.::|||||.:|...|:.|||::...||||::|.
 Worm  1001 LTMGS--RSYLQPEDFYEMLMDVIHTHPGLAFYRDATEFHDKYCQVVMTRIFWNDAHSWSGRLTT 1063

  Fly   655 AELKRSDLLEMISLLEEEEDINQIMAFFSYEHFYVIYCKFWELDKDHDLLINQEDLAKHSDHALS 719
            ..|::..:|:.|..|:.::|||:.:.:||||||||:||||||:|.||||.|:..|||:|:..||.
 Worm  1064 ERLRKGGVLQAIRNLQFDDDINKSLRYFSYEHFYVVYCKFWEIDSDHDLKISSTDLAQHAGGALV 1128

  Fly   720 SRIVERIFSGCVTRSDNKKAPEDEAKMSYTDFVWFILSEEDKRTPTAIEYWFRCMDVDGDGVLSM 784
            ..:|:|||||.|..:.|:..|.::  :...:|..|:|:||||..||:||||||.:|:||||::::
 Worm  1129 PMVVDRIFSGAVCTNPNRGQPVED--IGLAEFTQFLLAEEDKTHPTSIEYWFRILDLDGDGLVTL 1191

  Fly   785 YELEYFYEEQQQRMEGIGIECLPFEDCLCQMLDMIK-PANRDCITLGDLKRCKMTHVFFDTFFNL 848
            |::|.|:.:.|:::...||:.:.|.|..||::||:. |.......|.|||:..:...|.:||.|.
 Worm  1192 YDMELFHTQVQRKLAAEGIDSMGFADVACQLIDMLNVPGGVSAFRLSDLKKSSLRGRFINTFVNW 1256

  Fly   849 EKYLDHEQRDPFASQRDE-----YTSDWDRFAAQEYELLISEE 886
            .|:...|..:...|.|.|     ..::|||:..:|||.::.::
 Worm  1257 RKFFAQETNEGSESPRIEDEGGQELTEWDRYCIEEYEAMMEDD 1299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4733	NP_650842.2	PPP2R3A_B-like	572..851	CDD:410337	125/279 (45%)
F43B10.1	NP_001335569.1	PHA03247	<473..937	CDD:223021	96/511 (19%)
		PPP2R3A_B-like	983..1259	CDD:410337	125/279 (45%)