DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and valopa

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_571661.1	Gene:	valopa / 58109	ZFINID:	ZDB-GENE-000427-4	Length:	377	Species:	Danio rerio

Alignment Length:	374	Identity:	92/374 - (24%)
Similarity:	169/374 - (45%)	Gaps:	66/374 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 AVAAAQLGPHFAPLSNGSVVDKVTPDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNG 69
            ||:.|: .|..||||:              |:| ||.         .:|.|.|.::..:|...|.
Zfish    10 AVSPAE-DPFSAPLSS--------------IAP-WNY---------SVLAALMFVVTALSLSENF 49

  Fly    70 VVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFG 134
            .|:.:....:.||.|.|.:::||:::||.:.:|...:..:..|...:.||...|.:.....:.||
Zfish    50 TVMLVTFRFQQLRQPLNYIIVNLSLADFLVSLTGGSISFLTNYHGYFFLGKWACVLEGFAVTFFG 114

  Fly   135 CSSIWSMCMISLDRYQVIVKGMAGRPM-TIPL-----ALGKIAYIWFMSSIWCLAPAFGWSRYVP 193
            ..::||:.:::.:|:.||.     ||: .|.|     ||| :.::|..|.||.:.|..|||.|..
Zfish   115 IVALWSLAVLAFERFFVIC-----RPLGNIRLRGKHAALG-LVFVWSFSFIWTVPPVLGWSSYTV 173

  Fly   194 EGNLTSCGIDYLERDWNPRSYLI--FYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMN 256
            ....|:|..::...:::..:::|  |.:.|::.:.:.::||.            |.:|:..|..|
Zfish   174 SRIGTTCEPNWYSGNFHDHTFIITLFSTCFIFPLGVIIVCYC------------KLIRKLRKVSN 226

  Fly   257 VKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPY----LVINCMGLFKFEGLTPLNTIWGACF 317
            ......:   .:..|.::.::.:|.|..:.:|||||    ::|........:   |......|..
Zfish   227 THGRLGN---ARKPERQVTRMVVVMIVAFMVAWTPYAAFSIIITAHPSMHVD---PRLAAIPAFV 285

  Fly   318 AKSAACYNPIVYGISHPKYRLALKEKCPCCVFGKVD--DGKSSDAQSQA 364
            ||:||.||||:|...:.::|..|.:...|   .||.  :|.::....:|
Zfish   286 AKTAAVYNPIIYVFMNKQFRKCLVQLLSC---SKVTVVEGNNNQTTERA 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	74/299 (25%)
		TM helix 1	53..77	CDD:320207	6/23 (26%)
		TM helix 2	86..108	CDD:320207	6/21 (29%)
		TM helix 3	124..146	CDD:320207	4/21 (19%)
		TM helix 4	168..184	CDD:320207	5/15 (33%)
		TM helix 5	212..235	CDD:320207	5/24 (21%)
		TM helix 6	275..297	CDD:320207	8/25 (32%)
		TM helix 7	308..333	CDD:320207	11/24 (46%)
valopa	NP_571661.1	7tm_1	47..297	CDD:278431	68/273 (25%)
valopa	NP_571661.1	7tm_4	<95..314	CDD:304433	59/242 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910