DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and opn7a

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001303877.1	Gene:	opn7a / 570397	ZFINID:	ZDB-GENE-140106-15	Length:	455	Species:	Danio rerio

Alignment Length:	327	Identity:	86/327 - (26%)
Similarity:	148/327 - (45%)	Gaps:	32/327 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 FPAMDPIWAKILTAYMI-MIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTP 105
            |.:..|:.|.|....:. :.|:.|.|||.:::|:....|.|..||...::||||||.|:.::..|
Zfish     9 FQSNIPVAADITVGIVYSLFGVCSLCGNSMLLYVSYKKKHLLKPAEFFIVNLAISDLGMTLSLYP 73

  Fly   106 MMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKI 170
            :...:.....|:.|..:|.|||..|..||..|:.::.::|......:...:.|...:.......|
Zfish    74 LAVTSSIAHRWLYGRTVCVIYAFCGVLFGICSLTTLTILSTVCCLKVCYPLHGNRFSYEHGRMLI 138

  Fly   171 AYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWN--PRSYLIFYSIFVYYIPLFLICYS 233
            ...|..|.::..:|...|.:|.||...|:|.||:...:.|  .|||.....|..|.:|..:|..|
Zfish   139 VCAWAYSLVFACSPLAHWGQYGPEPYGTACCIDWAWSNQNSVARSYTTVLFIACYLVPCVIIIIS 203

  Fly   234 YWFIIAAVSAHEKAMRE----QAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLV 294
            |..|:..|....:|:.:    |.:..|::::             :.|:::.....:|.||:||.:
Zfish   204 YTRILITVRESRRAVEQHVSAQTRMGNIQTI-------------IVKLSVAVCIGFFTAWSPYAL 255

  Fly   295 INCMGLF-KFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYR-LALKE----------KCPCC 347
            ::....| .|:.:.|:.....|.||||:..|||::|.:..|.:| |..|:          .|.|.
Zfish   256 VSMWAAFGHFDDIPPMAFAVPAMFAKSSTLYNPLIYLLLKPNFRHLLCKDMRSLRGVCMHHCLCQ 320

  Fly   348 VF 349
            .|
Zfish   321 CF 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	79/296 (27%)
		TM helix 1	53..77	CDD:320207	6/24 (25%)
		TM helix 2	86..108	CDD:320207	8/21 (38%)
		TM helix 3	124..146	CDD:320207	7/21 (33%)
		TM helix 4	168..184	CDD:320207	3/15 (20%)
		TM helix 5	212..235	CDD:320207	8/22 (36%)
		TM helix 6	275..297	CDD:320207	6/21 (29%)
		TM helix 7	308..333	CDD:320207	10/24 (42%)
opn7a	NP_001303877.1	7TM_GPCR_Srd	23..235	CDD:304638	57/224 (25%)
opn7a	NP_001303877.1	7tm_1	35..291	CDD:278431	71/268 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910