DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and valopb

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001103750.1	Gene:	valopb / 560921	ZFINID:	ZDB-GENE-040724-41	Length:	392	Species:	Danio rerio

Alignment Length:	362	Identity:	86/362 - (23%)
Similarity:	155/362 - (42%)	Gaps:	70/362 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MESFAVAAAQLGPHFAPLSNGSVVDKVTPDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISW 65
            ||||..:..:            ..|..|||     .|:.....::.|.....|...|.::..:|.
Zfish     1 MESFGFSVTE------------STDVTTPD-----DPFKGPLKSVAPWNYTFLACLMFIVTSLSI 48

  Fly    66 CGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFET-----WVLGPMMCDI 125
            ..|..|:.:....|.||.|.|.:::||:::||.:.:|     |..:.|.|     :.||...|.:
Zfish    49 TENFTVMLVTYRFKQLRKPLNYIIVNLSVADFLVSMT-----GGTISFLTNARGFFFLGVWACVL 108

  Fly   126 YAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGK-----IAYIWFMSSIWCLAPA 185
            .....:.||..::||:.:::.:|:.||.     ||:......||     :.::|..|.||.:.|.
Zfish   109 EGFAVTFFGIVALWSLAILAFERFFVIC-----RPLKNVRLGGKHAAMGLIFVWTFSFIWTIPPV 168

  Fly   186 FGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMRE 250
            .||:.|......|:|..::...::...:|:|.:.:..:.:||.:|..||          .|.|::
Zfish   169 LGWNSYTVSKIGTTCEPNWYSTNYYDHTYIITFFVTCFILPLGVIIISY----------GKLMQK 223

  Fly   251 QAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLNTIW-- 313
            ..|..|......:   .:..:.::|::.:|.|..:.:.||||...:..       :|...||:
Zfish   224 LRKVSNTHGRLGN---ARKPDREVARMVVVMIVAFMVGWTPYAAFSIT-------VTACPTIYID 278

  Fly   314 ------GACFAKSAACYNPIVYGISHPKYRLALKEKC 344
                  .|.|:|:||.||||:|...:.::|     ||
Zfish   279 PRLGSIPAFFSKTAAVYNPIIYVFMNKQFR-----KC 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	74/305 (24%)
		TM helix 1	53..77	CDD:320207	5/23 (22%)
		TM helix 2	86..108	CDD:320207	6/21 (29%)
		TM helix 3	124..146	CDD:320207	4/21 (19%)
		TM helix 4	168..184	CDD:320207	6/20 (30%)
		TM helix 5	212..235	CDD:320207	6/22 (27%)
		TM helix 6	275..297	CDD:320207	7/21 (33%)
		TM helix 7	308..333	CDD:320207	12/32 (38%)
valopb	NP_001103750.1	7tm_4	38..315	CDD:304433	75/308 (24%)
valopb	NP_001103750.1	7tm_1	50..300	CDD:278431	69/279 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910