DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and Opn3

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001178862.1	Gene:	Opn3 / 498289	RGDID:	1594385	Length:	400	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	86/328 - (26%)
Similarity:	156/328 - (47%)	Gaps:	55/328 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SPYWNQFPAMDPIWAKILTAY---MIMIGMISWCGNG---VVIYIFATTKSLRTPANLLVINLAI 94
            :|...:.||  |:::.  |||   .:::|.::..|.|   :|:.:::....||||.:|.::||::
  Rat    23 APAGTRSPA--PLFSP--TAYERLALLLGCLALLGVGGNLLVLLLYSKFPRLRTPTHLFLVNLSL 83

  Fly    95 SDFGIMITNTPMMGINLYFET-----WVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVK 154
            .|  ::::   :.|:...|.:     ||...:.|......||.||..||.::.:::.:||   ::
  Rat    84 GD--LLVS---LFGVTFTFASCLRNGWVWDAVGCAWDGFSGSLFGFVSITTLTVLAYERY---IR 140

  Fly   155 GMAGRPMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYS 219
            .:..|.:....|...|.|||..|..|..||..||:||:.:.:...|.:|:..:|.|..|:::|..
  Rat   141 VVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLF 205

  Fly   220 IFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDAEK-------SAEGKLAKV 277
            :....:|:.:|.:.|..|:                .:|:.||..||.:.       ..|.|:||:
  Rat   206 LGCLVVPMGIIAHCYGHIL----------------YSVRMLRCVEDLQTIQVIKMLRYEKKVAKM 254

  Fly   278 ALVTITLWFMAWTPY-----LVINCMGLFKFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYR 337
            ..:...::...|.||     ||:|..|..    :||..:|....||||:..|||::|.....|:|
  Rat   255 CFLMAFVFLTCWMPYVVTRFLVVNGYGHL----VTPTVSIVSYLFAKSSTVYNPVIYIFMIRKFR 315

  Fly   338 LAL 340
            .:|
  Rat   316 RSL 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	81/310 (26%)
		TM helix 1	53..77	CDD:320207	7/29 (24%)
		TM helix 2	86..108	CDD:320207	4/21 (19%)
		TM helix 3	124..146	CDD:320207	6/21 (29%)
		TM helix 4	168..184	CDD:320207	6/15 (40%)
		TM helix 5	212..235	CDD:320207	4/22 (18%)
		TM helix 6	275..297	CDD:320207	7/26 (27%)
		TM helix 7	308..333	CDD:320207	10/24 (42%)
Opn3	NP_001178862.1	7tm_GPCRs	64..317	CDD:421689	74/280 (26%)
		TM helix 2	74..101	CDD:410628	6/31 (19%)
		TM helix 3	112..142	CDD:410628	9/32 (28%)
		TM helix 4	150..172	CDD:410628	9/21 (43%)
		TM helix 5	197..227	CDD:410628	6/45 (13%)
		TM helix 6	246..276	CDD:410628	7/29 (24%)
		TM helix 7	286..311	CDD:410628	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910