Protein Alignment ninaE and Taar7c

DIOPT Version :10

• Sequence 1: NP_524407.1
• Gene: ninaE / 42367
• FlyBaseID: FBgn0002940
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_001009975.1
• Gene: Taar7c / 494535
• RGDID: 1359258
• Length: 358
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 84/339 - (24%)
• Similarity: 145/339 - (42%)
• Gaps: 55/339 - (16%)

  Fly    36 SPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIM 100
            |||       .|....||.|......:::.|||.:|:......:.|.:|||.||.:||.:|..:.
  Rat    40 SPY-------SPGSRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADLLVG 97

  Fly   101 ITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPL 165
            :|..|...:......|..|...|..::....:|..||::.:|.||||||..:     ..|:..|.
  Rat    98 LTVMPFSMVRSVEGCWYFGNTYCKFHSCFEGSFCYSSLFHLCFISLDRYIAV-----SDPLIYPT 157

  Fly   166 AL-----GK-IAYIWFMSSIWCLAPAFGWSRYVPEGNLTS-------CGIDYLERDWNPRSYLIF 217
            ..     || |.:.|.:|.|:..:..:..:......:|.|       |.: .:.:.|      :|
  Rat   158 RFTASISGKCITFSWLLSIIYSFSLLYTGANEAGLEDLVSALTCVGGCQV-AVNQSW------VF 215

  Fly   218 YSIFVYYIP--LFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSE---DAEKSAEGKLAKV 277
            .:..::.:|  :.:..||..|:||      |...:..:||:.::.|:||   |.....|.|.||.
  Rat   216 INFLLFLVPALVMMTVYSKIFLIA------KQQAQNIEKMSKQTARASESYKDRVAKRERKAAKT 274

  Fly   278 ALVTITLWFMAWTPYLVINCMGLFKFEGLTPLN----TIWGACFAKSAACYNPIVYGISHPKYRL 338
            ..:.:..:.::|.||.:.:.:..| ...:||..    .:| ..:..||  .||::|...:|.:|.
  Rat   275 LGIAVAAFLLSWLPYFIDSIIDAF-LGFITPTYMYEILVW-IVYYNSA--MNPLIYAFFYPWFRK 335

  Fly   339 ALKEKCPCCVFGKV 352
            |:|    ..|.||:
  Rat   336 AIK----LIVTGKI 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	75/309 (24%)
		TM helix 1	52..78	CDD:320207	7/25 (28%)
		TM helix 2	85..111	CDD:320207	9/25 (36%)
		TM helix 3	123..153	CDD:320207	11/29 (38%)
		TM helix 4	164..184	CDD:320207	7/25 (28%)
		TM helix 5	211..240	CDD:320207	6/30 (20%)
		TM helix 6	269..299	CDD:320207	7/29 (24%)
		TM helix 7	308..333	CDD:320207	7/28 (25%)
Taar7c	NP_001009975.1	7tm_GPCRs	49..337	CDD:475119	75/309 (24%)
		TM helix 1	50..74	CDD:410628	6/23 (26%)
		TM helix 2	83..105	CDD:410628	8/21 (38%)
		TM helix 3	121..143	CDD:410628	5/21 (24%)
		TM helix 4	166..182	CDD:410628	5/15 (33%)
		TM helix 5	210..233	CDD:410628	3/28 (11%)
		TM helix 6	272..294	CDD:410628	5/21 (24%)
		TM helix 7	305..330	CDD:410628	6/27 (22%)