DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ninaE and rrh

DIOPT Version :9

Sequence 1:NP_524407.1 Gene:ninaE / 42367 FlyBaseID:FBgn0002940 Length:373 Species:Drosophila melanogaster
Sequence 2:NP_001004654.1 Gene:rrh / 447916 ZFINID:ZDB-GENE-040912-94 Length:334 Species:Danio rerio


Alignment Length:290 Identity:84/290 - (28%)
Similarity:139/290 - (47%) Gaps:12/290 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 ILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETW 116
            |:.||:|..|:||...|.||:.:|...:.|||..|.::||||.:|.|:.....||...:....:|
Zfish    27 IVAAYLITAGVISLSSNIVVLLMFVKFRELRTATNAIIINLAFTDIGVAGIGYPMSAASDLHGSW 91

  Fly   117 VLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWC 181
            ..|.|.|.|||.|...||.:||..:.::::|||..|.:...|:.:|.......|...|..:..|.
Zfish    92 KFGYMGCQIYAALNIFFGMASIGLLTVVAIDRYLTICRPDIGQKLTTRSYTLLIVAAWLNAVFWS 156

  Fly   182 LAPAFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEK 246
            ..|..||:.|.|:....:|.|::...|.:..||.:......:.|||.::.|.|:.:.|.|     
Zfish   157 SMPIVGWAGYAPDPTGATCTINWRNNDTSFVSYTMTVITVNFIIPLSVMFYCYYNVSATV----- 216

  Fly   247 AMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPL-N 310
                  |:....:...|.:.:.|.:..:.|::::.|.::..||:||.::.....|......|. .
Zfish   217 ------KRFKASNCLDSINMDWSDQMDVTKMSVIMIVMFLAAWSPYSIVCLWASFGDPQKIPAPM 275

  Fly   311 TIWGACFAKSAACYNPIVYGISHPKYRLAL 340
            .|.....|||:..|||.:|.|::.|:|.|:
Zfish   276 AIIAPLLAKSSTFYNPCIYVIANKKFRRAI 305

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ninaENP_524407.1 7tmA_photoreceptors_insect 52..340 CDD:320207 83/288 (29%)
TM helix 1 53..77 CDD:320207 10/23 (43%)
TM helix 2 86..108 CDD:320207 9/21 (43%)
TM helix 3 124..146 CDD:320207 8/21 (38%)
TM helix 4 168..184 CDD:320207 3/15 (20%)
TM helix 5 212..235 CDD:320207 6/22 (27%)
TM helix 6 275..297 CDD:320207 6/21 (29%)
TM helix 7 308..333 CDD:320207 10/25 (40%)
rrhNP_001004654.1 7tm_1 43..294 CDD:278431 72/261 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG48050
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

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