DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and opn1lw2

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001002443.1	Gene:	opn1lw2 / 436716	ZFINID:	ZDB-GENE-040718-141	Length:	356	Species:	Danio rerio

Alignment Length:	379	Identity:	113/379 - (29%)
Similarity:	178/379 - (46%)	Gaps:	55/379 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 APLSNGSVV-----DKVTPDMAHLISPYWNQFPAMDPI----------WA-KILTAYMIMIGMIS 64
            |..:||:..     |:.|.|.|.   .|.|.....||.          |. .:.|.:|..:.:.|
Zfish     2 AEWANGAFAARRRGDETTRDNAF---SYTNSNNTRDPFEGPNYHIAPRWVYNVATVWMFFVVVAS 63

  Fly    65 WCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGL 129
            ...||:|:...|..|.||.|.|.:::||||:|.|..:.::.:..||..|..::||..|| |:.|.
Zfish    64 TFTNGLVLVATAKFKKLRHPLNWILVNLAIADLGETLFSSTISVINQVFGYFILGHPMC-IFEGY 127

  Fly   130 G-SAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVP 193
            . |..|.:.:||:.:||.:|:.|:.|...........|...|.:.|..:::||..|.||||||.|
Zfish   128 TVSVCGIAGLWSLTVISWERWVVVCKPFGNVKFDGKWASAGIIFSWVWAAVWCAPPIFGWSRYWP 192

  Fly   194 EGNLTSCGIDYLERDWNP--RSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMN 256
            .|..||||.|....:.:|  :||::...|....:||.:|...|..:..|:  |..|.::
Zfish   193 HGLKTSCGPDVFGGNEDPGVQSYMLVLMITCCILPLAIIILCYIAVFLAI--HAVAQQQ------ 249

  Fly   257 VKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGL----FKFEGLTPLNTIWGACF 317
                :.||..:| ||.:::::.:|.:..:.:.|.||....|...    :.|.   ||.....|.|
Zfish   250 ----KDSESTQK-AEKEVSRMVVVMVLAFCLCWGPYTAFACFAAANPGYAFH---PLAAAMPAYF 306

  Fly   318 AKSAACYNPIVYGISHPKYRLALKEKCPCCVFG-KVDDGKSSDAQSQATASEAE 370
            ||||..||||:|...:.::|:.:.:     :|| |||||      |:.:.|:.|
Zfish   307 AKSATIYNPIIYVFMNRQFRVCIMQ-----LFGKKVDDG------SEVSTSKTE 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	91/294 (31%)
		TM helix 1	53..77	CDD:320207	6/23 (26%)
		TM helix 2	86..108	CDD:320207	7/21 (33%)
		TM helix 3	124..146	CDD:320207	7/22 (32%)
		TM helix 4	168..184	CDD:320207	4/15 (27%)
		TM helix 5	212..235	CDD:320207	6/22 (27%)
		TM helix 6	275..297	CDD:320207	4/21 (19%)
		TM helix 7	308..333	CDD:320207	13/24 (54%)
opn1lw2	NP_001002443.1	7tm_4	57..>185	CDD:304433	40/128 (31%)
opn1lw2	NP_001002443.1	7tm_1	67..318	CDD:278431	86/267 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910