Protein Alignment ninaE and Taar7f

DIOPT Version :10

• Sequence 1: NP_524407.1
• Gene: ninaE / 42367
• FlyBaseID: FBgn0002940
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_001010839.1
• Gene: Taar7f / 435207
• MGIID: 3527447
• Length: 358
• Species: Mus musculus
• Alignment Length: 350
• Identity: 84/350 - (24%)
• Similarity: 145/350 - (41%)
• Gaps: 77/350 - (22%)

  Fly    36 SPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDF--G 98
            |||       .|....||.|......:::.|||.:|:......:.|.:|||.||.:||.:||  |
Mouse    40 SPY-------SPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVG 97

  Fly    99 IMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTI 163
            :|:  .|...:......|..|...|.::.....:|...|::.:|.||:|||..:     ..|:..
Mouse    98 VMV--MPFSMVRSVEGCWYFGDSYCKLHTCFDVSFCYCSLFHLCFISVDRYIAV-----SDPLAY 155

  Fly   164 PLALGKIAYIWFMSSI--------WCLAPAFGWSRYVPEGNLTSCGIDYL--------------E 206
            |..        |.:|:        |.|:.::|:|....  ..:..|::.|              .
Mouse   156 PTR--------FTASVSGKCITFSWLLSISYGFSLIYT--GASEAGLEDLVSSLTCVGGCQIAVN 210

  Fly   207 RDWNPRSYLIFYSIFVYYIP--LFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSE---DA 266
            :.|      :|.:..|:.||  :.:..||..|:||      |...:..:||:.::.|:|:   |.
Mouse   211 QTW------VFINFSVFLIPTLVMITVYSKIFLIA------KQQAQNIEKMSKQTARASDSYKDR 263

  Fly   267 EKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLNT----IWGACFAKSAACYNPI 327
            ....|.|.||...:.:..:.::|.||.:.:.:..| ...:||...    :| ..:..||  .||:
Mouse   264 VAKRERKAAKTLGIAVAAFLLSWLPYFIDSFIDAF-LGFITPTYVYEILVW-IVYYNSA--MNPL 324

  Fly   328 VYGISHPKYRLALKEKCPCCVFGKV 352
            :|...:|.:|.|:|    ..|.||:
Mouse   325 IYAFFYPWFRKAIK----LTVTGKI 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	75/320 (23%)
		TM helix 1	52..78	CDD:320207	7/25 (28%)
		TM helix 2	85..111	CDD:320207	11/27 (41%)
		TM helix 3	123..153	CDD:320207	9/29 (31%)
		TM helix 4	164..184	CDD:320207	5/27 (19%)
		TM helix 5	211..240	CDD:320207	8/30 (27%)
		TM helix 6	269..299	CDD:320207	7/29 (24%)
		TM helix 7	308..333	CDD:320207	7/28 (25%)
Taar7f	NP_001010839.1	7tm_GPCRs	49..337	CDD:475119	75/320 (23%)
		TM helix 1	50..74	CDD:410628	6/23 (26%)
		TM helix 2	83..105	CDD:410628	10/23 (43%)
		TM helix 3	121..143	CDD:410628	4/21 (19%)
		TM helix 4	166..182	CDD:410628	3/15 (20%)
		TM helix 5	210..233	CDD:410628	5/28 (18%)
		TM helix 6	272..294	CDD:410628	5/21 (24%)
		TM helix 7	305..330	CDD:410628	6/27 (22%)