DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and Rh2

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_524398.1	Gene:	Rh2 / 42261	FlyBaseID:	FBgn0003248	Length:	381	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	256/368 - (69%)
Similarity:	294/368 - (79%)	Gaps:	3/368 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AQLGPHFAPLS--NGSVVDKVTPDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVV 71
            |..||.|...|  ||||:|.|.||||||::|||::|..|||:.:|||..:.:.|.:||.||||||
  Fly    14 AHSGPRFQAQSSGNGSVLDNVLPDMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVV 78

  Fly    72 IYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCS 136
            :|||..||||||||||||:|||.|||.:|.:.:|:|.||.|:|||||||:.||||||.||.|||.
  Fly    79 VYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCV 143

  Fly   137 SIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCG 201
            ||||||||:.|||.|||||:.|.||||..::.||.:||.|:..|.:.|..|||.||||||||:|.
  Fly   144 SIWSMCMIAFDRYNVIVKGINGTPMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACS 208

  Fly   202 IDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDA 266
            |||:.|.||||||||.||:||||.||||||||||||||||:|||||||||||||||||||||||.
  Fly   209 IDYMTRMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDC 273

  Fly   267 EKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLNTIWGACFAKSAACYNPIVYGI 331
            :||||||||||||.||:||||||||||||...||||.:|||||.|||||.|||::|.||||||||
  Fly   274 DKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFKIDGLTPLTTIWGATFAKTSAVYNPIVYGI 338

  Fly   332 SHPKYRLALKEKCPCCVFGKVDDGK-SSDAQSQATASEAESKA 373
            ||||||:.||||||.||||..|:.| .:.|....|.|||:|||
  Fly   339 SHPKYRIVLKEKCPMCVFGNTDEPKPDAPASDTETTSEADSKA 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	211/287 (74%)
		TM helix 1	53..77	CDD:320207	13/23 (57%)
		TM helix 2	86..108	CDD:320207	12/21 (57%)
		TM helix 3	124..146	CDD:320207	18/21 (86%)
		TM helix 4	168..184	CDD:320207	6/15 (40%)
		TM helix 5	212..235	CDD:320207	19/22 (86%)
		TM helix 6	275..297	CDD:320207	19/21 (90%)
		TM helix 7	308..333	CDD:320207	19/24 (79%)
Rh2	NP_524398.1	7tm_4	67..>237	CDD:304433	115/169 (68%)
Rh2	NP_524398.1	7tm_1	74..336	CDD:278431	195/261 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461663
Domainoid	1	1.000	192	1.000	Domainoid score	I3159
eggNOG	1	0.900	-	-		E33208_3BCHK
Homologene	1	1.000	-	-		H69152
Inparanoid	1	1.050	212	1.000	Inparanoid score	I3623
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48050
OrthoDB	1	1.010	-	-		D389088at33208
OrthoFinder	1	1.000	-	-		FOG0001799
OrthoInspector	1	1.000	-	-		mtm6356
orthoMCL	1	0.900	-	-		OOG6_104608
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
	12	11.710