DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and Opn5

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	XP_038939470.1	Gene:	Opn5 / 316259	RGDID:	727869	Length:	533	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	101/347 - (29%)
Similarity:	149/347 - (42%)	Gaps:	54/347 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 DPI-----WAKILTA--YMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN 103
            ||.     |...|.|  |:.:||::|..|||.|:|:.:..|....||.::.||||:.|.||.:..
  Rat    22 DPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVG 86

  Fly   104 TPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALG 168
            .|...|:.:...||.|...|..|...|..|||.|:.:|..:|||||..|.....|..:....|..
  Rat    87 KPFTIISCFCHRWVFGWFGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYI 151

  Fly   169 KIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRS------YLIFYSIFVYYIPL 227
            .:|.||..:|.|...|..|...|.||...|||.:|:    |..::      :::....|...:|.
  Rat   152 CLAVIWAYASFWTTMPLVGLGDYAPEPFGTSCTLDW----WLAQASGGGQVFILSILFFCLLLPT 212

  Fly   228 FLICYSYWFIIAAVS------AHEKAMREQAKKMNVKSLRSSEDAEKSAE--------------- 271
            .:|.:||..|||.|.      ||..:....:..:.||..:....|:.|.|
  Rat   213 AVIVFSYAKIIAKVKSSSKEVAHFDSRIHSSHVLEVKLTKGLVRADSSPESLPRSVFSTAEPINC 277

  Fly   272 -------GKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLN-TIWGACFAKSAACYNPIV 328
                   .:::.||::....:.:||.||.|::....|......|:. ::.....|||||.||||:
  Rat   278 HVLSISHSRVSTVAMLICAGFLIAWIPYAVVSVWSAFGRPNSIPIQLSVVPTLLAKSAAMYNPII 342

  Fly   329 YGISHPKYRLALKEKCPCCVFG 350
            |.:.  .||.|      ||..|
  Rat   343 YQVI--DYRFA------CCQTG 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	94/324 (29%)
		TM helix 1	53..77	CDD:320207	11/25 (44%)
		TM helix 2	86..108	CDD:320207	8/21 (38%)
		TM helix 3	124..146	CDD:320207	7/21 (33%)
		TM helix 4	168..184	CDD:320207	5/15 (33%)
		TM helix 5	212..235	CDD:320207	4/28 (14%)
		TM helix 6	275..297	CDD:320207	7/21 (33%)
		TM helix 7	308..333	CDD:320207	11/25 (44%)
Opn5	XP_038939470.1	7tmA_Opsin5_neuropsin	34..353	CDD:320202	95/330 (29%)
		TM helix 1	36..60	CDD:320202	10/23 (43%)
		TM helix 2	69..91	CDD:320202	8/21 (38%)
		TM helix 3	107..129	CDD:320202	7/21 (33%)
		TM helix 4	151..167	CDD:320202	5/15 (33%)
		TM helix 5	197..220	CDD:320202	4/22 (18%)
		TM helix 6	251..310	CDD:320202	10/58 (17%)
		TM helix 7	322..347	CDD:320202	10/26 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910