DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and opn1mw1

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_571328.2	Gene:	opn1mw1 / 30503	ZFINID:	ZDB-GENE-990604-42	Length:	349	Species:	Danio rerio

Alignment Length:	377	Identity:	103/377 - (27%)
Similarity:	179/377 - (47%)	Gaps:	65/377 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FAPLSNGSVVDKVTPDMAHLISPY-WNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATT 78
            :.|:||.:.:.:         ||| :.|:...:|...|.|..||.::.:..:..|.:.:.:.|..
Zfish    10 YIPMSNRTGLVR---------SPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQH 65

  Fly    79 KSLRTPANLLVINLAISDFGIMITNTPMMGINLYFET-----WVLGPMMC---DIYAGLGSAFGC 135
            |.||.|.|.:::|||.:. .||:    :.|..:.|..     ..|||:.|   ..:|.||   |.
Zfish    66 KKLRQPLNYILVNLAFAG-TIMV----IFGFTVSFYCSLVGYMALGPLGCVMEGFFATLG---GQ 122

  Fly   136 SSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSC 200
            .::||:.:::::||.|:.|.|.....:...|:..||:.|||:....:.|.||||||:|||..|||
Zfish   123 VALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSC 187

  Fly   201 GIDY--LERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSS 263
            |.||  |..::|..||:::.....:.||:..|.::|..::..|.|.....:|            |
Zfish   188 GPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQE------------S 240

  Fly   264 EDAEKSAEGKLAKVALVTITLWFMAWTPY------LVINCMGLFKFEGL-TPLNTIWGACFAKSA 321
            |..:| ||.::.::.::.:..:..||.||      :..|....|..:.: .|      |.|:|::
Zfish   241 ESTQK-AEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVP------AFFSKTS 298

  Fly   322 ACYNPIVYGISHPKYRLALKEKCPCCVFGKVDDGKS---SDAQSQATASEAE 370
            |.:|||:|.:.:.::|        .|:...:..|||   .|..|..:.|:.|
Zfish   299 AVFNPIIYVLLNKQFR--------SCMLNTLFCGKSPLGDDESSSVSTSKTE 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	86/304 (28%)
		TM helix 1	53..77	CDD:320207	4/23 (17%)
		TM helix 2	86..108	CDD:320207	6/21 (29%)
		TM helix 3	124..146	CDD:320207	6/21 (29%)
		TM helix 4	168..184	CDD:320207	5/15 (33%)
		TM helix 5	212..235	CDD:320207	5/22 (23%)
		TM helix 6	275..297	CDD:320207	4/27 (15%)
		TM helix 7	308..333	CDD:320207	9/24 (38%)
opn1mw1	NP_571328.2	Rhodopsin_N	2..37	CDD:287397	8/35 (23%)
		7tm_4	45..>222	CDD:304433	58/184 (32%)
		7tm_1	55..306	CDD:278431	81/277 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..349		4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48050
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920