Protein Alignment ninaE and Taar7e

DIOPT Version :10

• Sequence 1: NP_524407.1
• Gene: ninaE / 42367
• FlyBaseID: FBgn0002940
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_001010835.1
• Gene: Taar7e / 276742
• MGIID: 3527445
• Length: 358
• Species: Mus musculus
• Alignment Length: 348
• Identity: 83/348 - (23%)
• Similarity: 146/348 - (41%)
• Gaps: 73/348 - (20%)

  Fly    36 SPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIM 100
            |||       .|....||.|......:::.|||.:|:......:.|.:|||.||.:||.:||.:.
Mouse    40 SPY-------SPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVG 97

  Fly   101 ITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPL 165
            :|..|...:......|..|.:.|.::.....:|..|||:.:|.||:|||..:     ..|:..|.
Mouse    98 LTVMPFSTVRSVEGCWYFGEIYCKLHTCFDVSFCSSSIFHLCFISVDRYIAV-----SDPLIYPT 157

  Fly   166 ALGKIAYIWFMSSI--------WCLAPAFGWSRYVPEGNLTSCGIDYL--------------ERD 208
            .        |.:|:        |.|:.::|:|....  ..:..|::.|              .:.
Mouse   158 R--------FTASVSNKCITFSWLLSISYGFSLIYT--GASEAGLEDLVSALTCVGGCQLAVNQS 212

  Fly   209 WNPRSYLIFYSIFVYYIP--LFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSE---DAEK 268
            |      :|.:..::.||  :.:..||..|:||      |...:..:||:.::.|:|:   |...
Mouse   213 W------VFINFLLFLIPTLVMITVYSKIFLIA------KQQAQNIEKMSKQTARASDSYKDRVA 265

  Fly   269 SAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLNT----IWGACFAKSAACYNPIVY 329
            ..|.|.||...:.:..:.::|.||.:.:.:..| ...:||...    :|.|.:   .:..||::|
Mouse   266 KRERKAAKTLGIAVAAFLLSWLPYFIDSFIDAF-LGFITPTYVYEILVWIAYY---NSAMNPLIY 326

  Fly   330 GISHPKYRLALKEKCPCCVFGKV 352
            ...:|.:|.|:|    ..|.||:
Mouse   327 AFFYPWFRKAIK----LTVTGKI 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	74/318 (23%)
		TM helix 1	52..78	CDD:320207	7/25 (28%)
		TM helix 2	85..111	CDD:320207	10/25 (40%)
		TM helix 3	123..153	CDD:320207	11/29 (38%)
		TM helix 4	164..184	CDD:320207	5/27 (19%)
		TM helix 5	211..240	CDD:320207	7/30 (23%)
		TM helix 6	269..299	CDD:320207	7/29 (24%)
		TM helix 7	308..333	CDD:320207	6/28 (21%)
Taar7e	NP_001010835.1	7tm_GPCRs	49..337	CDD:475119	74/318 (23%)
		TM helix 1	50..74	CDD:410628	6/23 (26%)
		TM helix 2	83..105	CDD:410628	9/21 (43%)
		TM helix 3	121..143	CDD:410628	6/21 (29%)
		TM helix 4	166..182	CDD:410628	3/15 (20%)
		TM helix 5	210..233	CDD:410628	4/28 (14%)
		TM helix 6	272..294	CDD:410628	5/21 (24%)
		TM helix 7	305..330	CDD:410628	5/27 (19%)