DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ninaE and RRH

DIOPT Version :9

Sequence 1:NP_524407.1 Gene:ninaE / 42367 FlyBaseID:FBgn0002940 Length:373 Species:Drosophila melanogaster
Sequence 2:NP_006574.1 Gene:RRH / 10692 HGNCID:10450 Length:337 Species:Homo sapiens


Alignment Length:302 Identity:89/302 - (29%)
Similarity:149/302 - (49%) Gaps:24/302 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 ILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETW 116
            |:..|:||.||||...|.:|:.||...|.||||.|.::||||::|.|:.....||...:..:.:|
Human    27 IVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSW 91

  Fly   117 VLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWC 181
            ..|...|.:||||...||.:||..:.::::|||..|.....||.||....:|.|...|.....|.
Human    92 KFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWA 156

  Fly   182 LAPAFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAH-- 244
            |.|..||:.|.|:....:|.|::.:.|.:..||.:......:.:||.::.|.|:.:..::..|  
Human   157 LMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTT 221

  Fly   245 ----EKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF-KFE 304
                |...|:.:.:::|                 .|::::.|.::.:||:||.::.....| ..:
Human   222 SDCTESLNRDWSDQIDV-----------------TKMSVIMICMFLVAWSPYSIVCLWASFGDPK 269

  Fly   305 GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC 346
            .:.|...|....||||:..|||.:|.:::.|:|.|:.....|
Human   270 KIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKC 311

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ninaENP_524407.1 7tmA_photoreceptors_insect 52..340 CDD:320207 87/294 (30%)
TM helix 1 53..77 CDD:320207 11/23 (48%)
TM helix 2 86..108 CDD:320207 9/21 (43%)
TM helix 3 124..146 CDD:320207 8/21 (38%)
TM helix 4 168..184 CDD:320207 5/15 (33%)
TM helix 5 212..235 CDD:320207 5/22 (23%)
TM helix 6 275..297 CDD:320207 6/21 (29%)
TM helix 7 308..333 CDD:320207 10/24 (42%)
RRHNP_006574.1 7tmA_Peropsin 26..305 CDD:320201 87/294 (30%)
TM helix 1 27..53 CDD:320201 12/25 (48%)
TM helix 2 60..87 CDD:320201 9/26 (35%)
TM helix 3 98..128 CDD:320201 12/29 (41%)
TM helix 4 141..159 CDD:320201 5/17 (29%)
TM helix 5 186..216 CDD:320201 6/29 (21%)
TM helix 6 233..263 CDD:320201 7/46 (15%)
TM helix 7 273..298 CDD:320201 10/24 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG48050
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.