DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and opn5

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	XP_002936036.1	Gene:	opn5 / 100497642	XenbaseID:	XB-GENE-1018909	Length:	343	Species:	Xenopus tropicalis

Alignment Length:	314	Identity:	95/314 - (30%)
Similarity:	146/314 - (46%)	Gaps:	31/314 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 DPIWAKI-------LTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN 103
            ||..:|:       ...|::.||::|..|||.|||:..:.|....||.::.||||:.|.||.:|.
Frog    22 DPFASKLSREADIFAGVYLMAIGILSTLGNGYVIYMACSRKKKLRPAEIMTINLAVCDLGISVTG 86

  Fly   104 TPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALG 168
            .|...::.:...||.|...|..|...|..|||.|:.::.::|||||..|.....|..:....|..
Frog    87 KPFAIVSCFSHRWVFGWNACRWYGWAGFFFGCGSLITLTVVSLDRYLKICHLRYGTWLKRRHAFI 151

  Fly   169 KIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRS------YLIFYSIFVYYIPL 227
            .:|.||..:::|...|..|...|.||...|:|.:|:    |..::      :::....|....|.
Frog   152 ALAVIWAYATLWATLPLVGVGNYAPEPFGTTCTLDW----WLAQASVKGQIFVLSMLFFCLLFPT 212

  Fly   228 FLICYSYWFIIAAV--SAHEKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWT 290
            .:|.:||..|||.|  ||.|.|..:...:.|           .:.|.||.|||::....:.:||.
Frog   213 MVIVFSYAKIIAKVKSSAKEVAHFDTRNQNN-----------HTLEIKLTKVAMLICAGFLIAWF 266

  Fly   291 PYLVINCMGLFKFEGLTPLN-TIWGACFAKSAACYNPIVYGISHPKYRLALKEK 343
            ||.|::....|......|:. ::.....||||:.||||:|.:...|.....|:|
Frog   267 PYAVVSVWSAFGQPDSIPIELSVVPTMMAKSASMYNPIIYQVIDCKPACCKKDK 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	90/303 (30%)
		TM helix 1	53..77	CDD:320207	10/23 (43%)
		TM helix 2	86..108	CDD:320207	9/21 (43%)
		TM helix 3	124..146	CDD:320207	6/21 (29%)
		TM helix 4	168..184	CDD:320207	4/15 (27%)
		TM helix 5	212..235	CDD:320207	4/28 (14%)
		TM helix 6	275..297	CDD:320207	8/21 (38%)
		TM helix 7	308..333	CDD:320207	10/25 (40%)
opn5	XP_002936036.1	7tm_1	50..306	CDD:278431	84/270 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910