DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaE and opn1sw

DIOPT Version :9

Sequence 1:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001119548.1	Gene:	opn1sw / 100125215	XenbaseID:	XB-GENE-993052	Length:	349	Species:	Xenopus tropicalis

Alignment Length:	348	Identity:	95/348 - (27%)
Similarity:	159/348 - (45%)	Gaps:	33/348 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 ISPYWNQFPAMDPIWAKILTAYMIMIGMISWCG---NGVVIYIFATTKSLRTPANLLVINLAISD 96
            :||:......:.|.||..|.|  :.:|.:...|   |.:|:.:....|.||.|.|.:::|:|:..
Frog    18 VSPWDGPQYHIAPKWAFTLQA--LFMGAVFLFGAPLNLIVLVVTMKYKKLRQPLNYILVNIAVGG 80

  Fly    97 FGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPM 161
            |.:.|.:...:.|:.....:.||.:.|:|.|.:|:..|..:.||:..::.:||.||.|.|.....
Frog    81 FLMCIFSIFPVFISSSKGYFFLGKVACNIDAFIGTVSGLVTGWSLAFLAFERYIVICKPMGNFTF 145

  Fly   162 TIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRS--YLIFYSIFVYY 224
            :...|:..:...|.:.....:.|.||||||:|||...|||.|:.......||  |..|..||.:.
Frog   146 SSSHAMAVVICTWIIGIGVSVPPFFGWSRYMPEGLQCSCGPDWYTVGTKYRSEYYTWFIFIFCFV 210

  Fly   225 IPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAW 289
            :||.:||:||..::.|:.|.....:|.|             :.:.||.:::::.:|.:..:.:.:
Frog   211 MPLTMICFSYGRLLGALRAVAAQQQESA-------------STQKAEREVSRMVVVMVGSFCLCY 262

  Fly   290 TP------YLVINCMGLFKFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV 348
            .|      |:|.|     :..||........|.|:|||..||||:|...:.::|..:.|  ..|.
Frog   263 VPYAAMAMYMVTN-----RDHGLDLRLVTIPAFFSKSACVYNPIIYSFMNKQFRGCIME--TVCG 320

  Fly   349 FGKVDDGKSSDAQSQATASEAES 371
            ....||...|....:...|...|
Frog   321 RPMTDDSSVSSTSQKTEVSTVSS 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	83/298 (28%)
		TM helix 1	53..77	CDD:320207	6/26 (23%)
		TM helix 2	86..108	CDD:320207	5/21 (24%)
		TM helix 3	124..146	CDD:320207	6/21 (29%)
		TM helix 4	168..184	CDD:320207	1/15 (7%)
		TM helix 5	212..235	CDD:320207	11/24 (46%)
		TM helix 6	275..297	CDD:320207	4/27 (15%)
		TM helix 7	308..333	CDD:320207	10/24 (42%)
opn1sw	NP_001119548.1	7tmA_SWS1_opsin	35..314	CDD:320204	83/298 (28%)
		TM helix 1	36..62	CDD:320204	6/27 (22%)
		TM helix 2	69..96	CDD:320204	6/26 (23%)
		TM helix 3	107..137	CDD:320204	10/29 (34%)
		TM helix 4	148..170	CDD:320204	3/21 (14%)
		TM helix 5	197..227	CDD:320204	11/29 (38%)
		TM helix 6	242..272	CDD:320204	4/29 (14%)
		TM helix 7	282..307	CDD:320204	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910