DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ask1 and YDA

DIOPT Version :9

Sequence 1:	NP_477089.3	Gene:	Ask1 / 42366	FlyBaseID:	FBgn0014006	Length:	1363	Species:	Drosophila melanogaster
Sequence 2:	NP_001319310.1	Gene:	YDA / 842674	AraportID:	AT1G63700	Length:	883	Species:	Arabidopsis thaliana

Alignment Length:	399	Identity:	136/399 - (34%)
Similarity:	213/399 - (53%)	Gaps:	47/399 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   590 VLGKGTYGTVYAARDKQTQVRIAIKEV-----PEKNSQDVQPLHEEIKLHSQLRHRNIVRYLGSC 649
            :||.|::|.||...:.::....|:|||     ..|:.:..|.|.:||.:.|:|||:|||:|.||.
plant   405 LLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRLRHQNIVQYYGSE 469

  Fly   650 SENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNV 714
            :.:....|::|.|.|||:..||: ::|..  .|:.:..|::|||.||.|||.::.|||||||.|:
plant   470 TVDDKLYIYLEYVSGGSIYKLLQ-EYGQF--GENAIRNYTQQILSGLAYLHAKNTVHRDIKGANI 531

  Fly   715 LVNTYSGVVKISDFGTSKRL-ARINPMTETFTGTLQYMAPEVIDQGVRGYGPAADIWSFGCTNVE 778
            ||:.: |.||::|||.:|.: |:..|:  :|.|:..:|||||| :...|...|.||||.|||.:|
plant   532 LVDPH-GRVKVADFGMAKHITAQSGPL--SFKGSPYWMAPEVI-KNSNGSNLAVDIWSLGCTVLE 592

  Fly   779 MATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLEDPFL 843
            |||.|||:.:.... .||||:|..|:.|:||:.||...|:|:.:|...:..:||:|:|||:..|:
plant   593 MATTKPPWSQYEGV-PAMFKIGNSKELPDIPDHLSEEGKDFVRKCLQRNPANRPTAAQLLDHAFV 656

  Fly   844 QDKPRKVRP--------ALPINTEFGRSISVPADRFVHKTTPPLSYNTTCNTPTTPELDITHSSS 900
            ::.....||        |:.:.:...||:.:...|    :.|.|......|   ..:..:.|.|.
plant   657 RNVMPMERPIVSGEPAEAMNVASSTMRSLDIGHAR----SLPCLDSEDATN---YQQKGLKHGSG 714

  Fly   901 VDIDELPSNQ-----------FMLERRNSHGFLLSPEIEPSTPSLRTSISETSE--TDGFYRLKK 952
            ..|.:.|.|.           |     :||...:|....||..|...::|.:|.  |.....:..
plant   715 FSISQSPRNMSCPISPVGSPIF-----HSHSPHISGRRSPSPISSPHALSGSSTPLTGCGGAIPF 774

  Fly   953 DSQRRTTLS 961
            ..||:||::
plant   775 HHQRQTTVN 783

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ask1	NP_477089.3	DUF4071	74..444	CDD:290020
		STKc_ASK	576..843	CDD:270794	107/258 (41%)
		S_TKc	590..843	CDD:214567	107/258 (41%)
YDA	NP_001319310.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	209	1.000	Domainoid score	I802
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2588
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910