DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ask1 and MAPKKK5

DIOPT Version :9

Sequence 1:	NP_477089.3	Gene:	Ask1 / 42366	FlyBaseID:	FBgn0014006	Length:	1363	Species:	Drosophila melanogaster
Sequence 2:	NP_569040.1	Gene:	MAPKKK5 / 836819	AraportID:	AT5G66850	Length:	716	Species:	Arabidopsis thaliana

Alignment Length:	297	Identity:	120/297 - (40%)
Similarity:	178/297 - (59%)	Gaps:	27/297 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   590 VLGKGTYGTVYAARDKQTQVRIAIKEV---PE--KNSQDVQPLHEEIKLHSQLRHRNIVRYLGSC 649
            ::|:||:|:||.|.:.:|....|:|||   |:  |:::.::.|.:||||.|.|:|.|||:|.||.
plant   351 LIGRGTFGSVYVASNSETGALCAMKEVELFPDDPKSAECIKQLEQEIKLLSNLQHPNIVQYFGSE 415

  Fly   650 SENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNV 714
            :....|.|::|.|..||::..:....|.:  .||.:..:::.||.||.|||.:..|||||||.|:
plant   416 TVEDRFFIYLEYVHPGSINKYIRDHCGTM--TESVVRNFTRHILSGLAYLHNKKTVHRDIKGANL 478

  Fly   715 LVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQYMAPEVIDQGV--RGYGP----AADIWSFG 773
            ||:. |||||::|||.:|.|.. .....:..|:..:||||:: |.|  :...|    |.||||.|
plant   479 LVDA-SGVVKLADFGMAKHLTG-QRADLSLKGSPYWMAPELM-QAVMQKDSNPDLAFAVDIWSLG 540

  Fly   774 CTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLL 838
            ||.:||.|||||:.|...| ||||||  .:..|.|||.:|...|:|:..||..:..:||:||.||
plant   541 CTIIEMFTGKPPWSEFEGA-AAMFKV--MRDSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLL 602

  Fly   839 EDPFLQDKPRKVRPALPINTEF-----GRSISVPADR 870
            |..||::   .::|..|.|::.     |.:|:.|:.|
plant   603 EHRFLKN---SLQPTSPSNSDVSQLFNGMNITEPSSR 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ask1	NP_477089.3	DUF4071	74..444	CDD:290020
		STKc_ASK	576..843	CDD:270794	111/263 (42%)
		S_TKc	590..843	CDD:214567	111/263 (42%)
MAPKKK5	NP_569040.1	PKc_like	346..607	CDD:419665	111/263 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	209	1.000	Domainoid score	I802
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2588
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910