| Sequence 1: | NP_477089.3 | Gene: | Ask1 / 42366 | FlyBaseID: | FBgn0014006 | Length: | 1363 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001156557.2 | Gene: | Map3k15 / 270672 | MGIID: | 2448588 | Length: | 1331 | Species: | Mus musculus |
| Alignment Length: | 1341 | Identity: | 574/1341 - (42%) |
|---|---|---|---|
| Similarity: | 787/1341 - (58%) | Gaps: | 165/1341 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 21 ALEEIKQAVQSAGANFQRVQFERLDFGETNVLETFYNADVAIIDLSILTQQRPLSYHYGVRESFG 85
Fly 86 MKENILTYNDIDSKQTLSLK--------LSCANYLFLSYKRN--AETNSCHLTSQPNSGNNSKEP 140
Fly 141 NAEGRVPTLQW-------------RLKRKLQDVEIQSKAHMREKFLSDMRTARDTYATNGAKLQS 192
Fly 193 ILHEMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAMVRLVNDLKNIPNTRKYVETGNMSFLYAFA 257
Fly 258 LNRRNRKGDREKALESSLKALEKKENHFPDMLCLCGRIYKDIFVESDYTDATSLAHAIKWYRQSF 322
Fly 323 EVQPNEYAGINLATLLVIEGKEFTNTEELQHIGMTLNNLIGKKGSLSSLSEYWDVATFFEISVLA 387
Fly 388 NDYAKAIQAAECMFKLKPPNWYLKSTIGNISLIHRFRKKPEERQPPIEEQVFQFWMDFFLEATNT 452
Fly 453 EEVKNSIRFPILILEPQKIYMPSYVTINMDADEKSIQIVNICLAHAKNACKKIHDFLFVASKIKS 517
Fly 518 VSLYKRDDRCAYLYVHHNSDDFQIYFPSTERRQKFYDMILEMTADQV---VFVNLSNDDANIEYE 579
Fly 580 YDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLRHRNIVR 644
Fly 645 YLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDI 709
Fly 710 KGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQYMAPEVIDQGVRGYGPAADIWSFGC 774
Fly 775 TNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLE 839
Fly 840 DPFLQ--DKPRKVRPALPINTEFGRSISVPADRFVHKTTPPLSYNT-TCNTPTTPELDITHSS-- 899
Fly 900 ---SVDIDELPSNQF----MLERRNSHGFLLS-PEIEPSTPSLRTSISETSETDGFYRLKKDSQR 956
Fly 957 RTTLSKVLALDESKICDIWLKKVDADQNSIAIRKSDLEVLIRGLRDYIMNENEKHLEATINELKQ 1021
Fly 1022 KLNNDAVALDHLHLALYSFQDAVVCVLRYHCIKPHWMFALDNLVKRAVQAAVTIFSPELGANL-- 1084
Fly 1085 ------ADKDLSGNDDESLRTSLMQK----------GSTESQEKQSLEKVLPTSNTREGVGLTPA 1133
Fly 1134 ESGGDALSSSMECARILRDIRDNQQKLQRQLLEQQRQSMRALHNI----SQELAHIYMGGRKRLR 1194
Fly 1195 RTINGFNKKCHRMSTSVGGTSGVRPNIAGNPRRQLNKHHFGLHEVDEQLEQWLTQQEIDEFSKTL 1259
Fly 1260 ILNEGFTFDDFIYNMEKLDLMRLGLRVGIEVRLWKLIIQER 1300 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ask1 | NP_477089.3 | DUF4071 | 74..444 | CDD:290020 | 168/392 (43%) |
| STKc_ASK | 576..843 | CDD:270794 | 188/266 (71%) | ||
| S_TKc | 590..843 | CDD:214567 | 182/252 (72%) | ||
| Map3k15 | NP_001156557.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..61 | ||
| DUF4071 | 140..518 | CDD:290020 | 168/392 (43%) | ||
| STKc_ASK | 647..912 | CDD:270794 | 188/266 (71%) | ||
| S_TKc | 661..912 | CDD:214567 | 182/252 (72%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 934..964 | 10/29 (34%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 983..1005 | 5/21 (24%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167848163 | |
| Domainoid | 1 | 1.000 | 384 | 1.000 | Domainoid score | I815 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4279 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H50401 | |
| Inparanoid | 1 | 1.050 | 959 | 1.000 | Inparanoid score | I333 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S2727 |
| OMA | 1 | 1.010 | - | - | QHG45642 | |
| OrthoDB | 1 | 1.010 | - | - | D122434at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001687 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42450 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104013 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR11584 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3835 |
| SonicParanoid | 1 | 1.000 | - | - | X1591 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 17 | 16.750 | |||||