Protein Alignment Ask1 and mkh1

DIOPT Version :9

• Sequence 1: NP_477089.3
• Gene: Ask1 / 42366
• FlyBaseID: FBgn0014006
• Length: 1363
• Species: Drosophila melanogaster
• Sequence 2: NP_593005.1
• Gene: mkh1 / 2542175
• PomBaseID: SPAC1F3.02c
• Length: 1116
• Species: Schizosaccharomyces pombe
• Alignment Length: 671
• Identity: 175/671 - (26%)
• Similarity: 268/671 - (39%)
• Gaps: 183/671 - (27%)

  Fly   229 VRLVNDLKNIPNTR-----KYVETGNMSFLYAFALNRRNRKGDREKALESSL--KALEKKENHFP 286
            :|..|.|...|:.|     .|::||:               .:..|...:|.  ||..|..|...
pombe   553 LRRKNTLTRRPSIRHARSSPYIDTGH---------------NEASKFSHTSFDPKASSKSSNSLK 602

  Fly   287 DMLCLCGRIYKDIFVESDYTDATSLAHAIKWY---RQSFEVQPNEYAGINLATLLVIEGKEFTNT 348
            :.:.....|   .|.::...|.:.|:....|.   :||....|.|                  |.
pombe   603 ESVEALSEI---PFEDAPALDESDLSGDPFWAIQPKQSSSQVPKE------------------NH 646

  Fly   349 EELQHIGMTLNNLIGKKGSLSSLSEYWDVATFFEISVLANDYAKAIQAAECMFKLKPPNWYLKST 413
            ..:|                |.||...:.||..:.:.|::.              |.|. |.:..
pombe   647 HNIQ----------------SKLSINTEAATDLKANELSSP--------------KTPE-YCRGD 680

  Fly   414 IGNIS---LIHRFRKKPEERQPPIEEQVFQF--W------------MDFFLEATNTEEVKNSIRF 461
            ..:||   |.:|.||....|:.|...:|...  |            :|.|....:.::|
pombe   681 DRSISLSPLSYRLRKSKHIRESPPSSKVINSGNWEVRPSADDLYEDVDRFFPRYDLDKV------ 739

  Fly   462 PILILEPQKIYMPSYVTINMDADEKSIQIVNICLAHAKNACKKIHDFLFVASKIKSVSLYKRDDR 526
             :::.:.:.:..||.|:|.                                .|:|||.|..|:..
pombe   740 -LVVDQSRMVSSPSKVSIR--------------------------------PKMKSVRLLAREAS 771

  Fly   527 CAYLYVHHNSDDFQIYFPSTERRQKFYDM------------ILEMTADQVVFVNLSNDDANIEYE 579
            .|...:.||:           ||.|..::            |:|:..|..: .:.|....|..::
pombe   772 EARKEIRHNA-----------RRNKSGNLLRRSSTKLWGSRIVELKPDTTI-TSGSVVSQNATFK 824

  Fly   580 YDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIK--EVPEK--------NSQDVQPLHEEIKLH 634
            :...|     ::|.||||.|:.|.:..|...||:|  |:|:.        ....|..::.||.:.
pombe   825 WMKGE-----LIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMI 884

  Fly   635 SQLRHRNIVRYLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYL 699
            :.|.|.|||:|||.........||:|.|.|||:...|. .:||.:  |..:.|.|:|:|.||.||
pombe   885 ADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLR-NYGPFE--EQLVRFVSRQVLYGLSYL 946

  Fly   700 HEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARI--NPMTETFTGTLQYMAPEVIDQGVRG 762
            |.:.|:|||:|.||:|:: :.||.||||||.||....:  |....:..|::.:||||||....:|
pombe   947 HSKGIIHRDLKADNLLID-FDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQG 1010

  Fly   763 YGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEEL----SANAKNFILRC 823
            |....|:||.||..:||..|:.|: ....|..||||:|..||.|.||.||    |..|..|:..|
pombe  1011 YSAKVDVWSLGCVVLEMLAGRRPW-STDEAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNAC 1074

  Fly   824 FAISVMDRPSASQLLEDPFLQ 844
            |.::...||:|.:||..||::
pombe  1075 FTVNADVRPTAEELLNHPFMK 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ask1	NP_477089.3	DUF4071	74..444	CDD:290020	44/241 (18%)
		STKc_ASK	576..843	CDD:270794	106/282 (38%)
		S_TKc	590..843	CDD:214567	105/268 (39%)
mkh1	NP_593005.1	STKc_Bck1_like	823..1094	CDD:270799	106/280 (38%)
		S_TKc	825..1094	CDD:214567	106/278 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	171	1.000	Domainoid score	I884
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto100506
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910