Protein Alignment Arc42 and IVD

DIOPT Version :10

• Sequence 1: NP_650840.1
• Gene: Arc42 / 42364
• FlyBaseID: FBgn0038742
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_016877638.1
• Gene: IVD / 3712
• HGNCID: 6186
• Length: 516
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 129/372 - (34%)
• Similarity: 197/372 - (52%)
• Gaps: 33/372 - (8%)

  Fly    23 SLSALSETHQMLQKSCRDFANNELSGNAAKFDREHLYPEKQI----------------------- 64
            :::.|||..:.|:::...|....|:..|.:.||.:.:...::
Human    41 AINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLRVSWEVRAVGGSQGVGLSCTAAWKS 105

  Fly    65 --------RQMGELGVMAVAIPEELGGTGLDYVAYAIAMEEISRGCASAGVIMSVNNSLYLGPLL 121
                    :|:|.|||:.:..|.:.||:||.|:.:.:.||||||...:.|:....:::|.:..|:
Human   106 SHSFLEFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLV 170

  Fly   122 SFGNDAQKKDYITPFTTGERVGCFALSEPGNGSDAGAASTIATDKGDHFVLNGTKAWITNAFEAE 186
            ..||:|||:.|:....:||.:|..|:|||..|||..:....|..||:|::|||.|.||||..:|:
Human   171 RNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDAD 235

  Fly   187 AAIVFATTNKQL--KHKGISAFIVPKATKGFSLGKKEDKLGIRGSSTCQLIFEDCVVPKENMLGE 249
            ..||:|.|:...  ..:||:||||.|...|||..||.||||:|||:||:||||||.:|..|:||.
Human   236 VLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGH 300

  Fly   250 PGFGFKIAMQTLDAGRIGIAGQALGIGQAALELAVDYAQKRQAFGKPIAKLQSIQQKIADMSLAM 314
            ...|..:.|..||..|:.:||..||:.||.|:..:.|...|:|||:.|...|.:|.|:|||...:
Human   301 ENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRL 365

  Fly   315 ESARLLTWRAAWLKDQKQPYTKEAAMAKLAASEAATLCSHQCIQILG 361
            .:.|...:..|...|:.....|:.|...|.::|.||..:...||..|
Human   366 MACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFG 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arc42	NP_650840.1	SCAD_SBCAD	29..401	CDD:173847	127/366 (35%)
IVD	XP_016877638.1	IVD	44..412	CDD:173845	128/367 (35%)