Protein Alignment CG4562 and ABCC1

DIOPT Version :9

• Sequence 1: NP_001262747.1
• Gene: CG4562 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Sequence 2: NP_001031116.1
• Gene: ABCC1 / 839920
• AraportID: AT1G30400
• Length: 1622
• Species: Arabidopsis thaliana
• Alignment Length: 1425
• Identity: 481/1425 - (33%)
• Similarity: 745/1425 - (52%)
• Gaps: 165/1425 - (11%)

  Fly     7 DELP--EN--PREKSNIFSSLMFCFAMPTFFKGRKKTLDENDLYRALQEHRSDHLGSKLSAAWEK 67
            :|||  ||  |...:|:|.|:.|.:..|....|.|:.|.|.|::......:::.|......:|:|
plant   217 EELPGGENICPERHANLFDSIFFSWLNPLMTLGSKRPLTEKDVWHLDTWDKTETLMRSFQKSWDK 281

  Fly    68 EVEKKRKKKKTPSLLKASMNVFGWRLAGLGLVLFILEIGFRVTQPLFLGGLVAYYADASNQEGDN 132
            |:||.:     |.||:|..|..|.|....|    ..:||...:|  |:|.|:......|.|..:.
plant   282 ELEKPK-----PWLLRALNNSLGGRFWWGG----FWKIGNDCSQ--FVGPLLLNELLKSMQLNEP 335

  Fly   133 QTKAYLYALGVILTSACNVLFMHPYMLGMFHIGMKARIAMTSMIYRKALRLSRTALGDTTIGQVV 197
            ....|:||:.:.:.....||....|...:..:|.:.|.|:.:.::||:|||:.........|::.
plant   336 AWIGYIYAISIFVGVVLGVLCEAQYFQNVMRVGYRLRSALIAAVFRKSLRLTNEGRKKFQTGKIT 400

  Fly   198 NLISNDVGRLDVSVIHMNYLWLGPVEIGIITYLMYREIGISAFFGVAVMLLFIPLQAYLGKKTSV 262
            ||::.|...|......::.:|..|..|.:...|:|:::|:::..|...::|..|:|..:..||..
plant   401 NLMTTDAESLQQICQSLHTMWSAPFRIIVALVLLYQQLGVASIIGALFLVLMFPIQTVIISKTQK 465

  Fly   263 LRLKTALRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRGTLQSFIM 327
            |..:...|||:|:.:|||:::.:..:|.||||..|...:..||..|::..|...    .|.:|.|
plant   466 LTKEGLQRTDKRIGLMNEVLAAMDTVKCYAWENSFQSKVQTVRDDELSWFRKAQ----LLSAFNM 526

  Fly   328 FV-TRISVFVSLVG---FVLLGKLLTAEKAFVITAYYNILRNTMTVYFPMGISQFAELLVSIRRI 388
            |: ..|.|.|::|.   |.|||..||..:||...:.:::||..:.: .|..|:|.....||:.|:
plant   527 FILNSIPVLVTVVSFGVFSLLGGDLTPARAFTSLSLFSVLRFPLFM-LPNIITQMVNANVSLNRL 590

  Fly   389 QTFMLHEETKVRDKSEDLDEQKLGKAGLIAEPTVAQTTGVLKPSSRRTSEAEHSIVISKLKAKWD 453
            :..:..||..                 |:..|.:              ...:.:|.|......||
plant   591 EEVLSTEERV-----------------LLPNPPI--------------EPGQPAISIRNGYFSWD 624

  Fly   454 QKNTDNTLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDS-GSVKVNGTLSYASQEPWL 517
            .|....||.||:|......||||:|..|.||:|||.|:||||...| .:|.:.|:::|..|..|:
plant   625 SKADRPTLSNINLDIPLGSLVAVVGSTGEGKTSLISAMLGELPARSDATVTLRGSVAYVPQVSWI 689

  Fly   518 FTGTVRQNILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASLSGGQKARISLARAV 582
            |..|||.|||||.|.|:.:|..|:...||:.|.||||..|.|.:||||.::|||||.|:|:||||
plant   690 FNATVRDNILFGAPFDQEKYERVIDVTALQHDLELLPGGDLTEIGERGVNISGGQKQRVSMARAV 754

  Fly   583 YRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQADVIVIMDKGKISAM 647
            |..:|:.:|||||||:|.|||:.:|::|::..|.:...:|||:||.||.|.|.|:::.:|.:...
plant   755 YSNSDVCILDDPLSALDAHVGQQVFEKCIKRELGQTTRVLVTNQLHFLSQVDKILLVHEGTVKEE 819

  Fly   648 GTYESMAKSGLDFAQMLTDPSKKDEGAGDAPDKKSLSRQNSKLRDRHGSISSMES---------- 702
            ||||.:..||..|.:::       |.||...|   .|.:|.:......|:..:|:
plant   820 GTYEELCHSGPLFQRLM-------ENAGKVED---YSEENGEAEVDQTSVKPVENGNANNLQKDG 874

  Fly   703 --AAESLAAESPMQTQEGRVEGRIGMKLYKKYFGANGYGLFIVFAFFC-IGAQVLASGGDIFLSY 764
              ...|....|.:..:|.|..|.:..|:.::|..|.|....::....| :..||.......:||.
plant   875 IETKNSKEGNSVLVKREERETGVVSWKVLERYQNALGGAWVVMMLVICYVLTQVFRVSSSTWLSE 939

  Fly   765 WVNKNGEAERDTFMARLRRAFPETRINADTDPV--DIYY----FTGINVSVI-IFSLVRSMLFFY 822
            |.:.               ..|:|.     .|:  :|.|    |..::|::| .:.|:.|.|:
plant   940 WTDS---------------GTPKTH-----GPLFYNIVYALLSFGQVSVTLINSYWLIMSSLY-- 982

  Fly   823 LAMRSSTTLHNTMFQGVTRAAMHFFNTNPSGRILNRFSKDLGQVDE---ILPSVMMDVMQIFLAI 884
                ::..:|:.|...:.||.|.||.|||.|||:|||:||:|.:|.   :..::.|..:...|:.
plant   983 ----AAKKMHDAMLGSILRAPMVFFQTNPLGRIINRFAKDMGDIDRTVAVFVNMFMGSIAQLLST 1043

  Fly   885 VGIVVVLCIINVWYILATVFLVIVFYLLRVFYLSTSRDVKRLEAVTRSPIYSHLSASLNGLATIR 949
            |.::.::..:::|.|:.   |::|||...::|.:|||::||:::.||||:|:....:||||::||
plant  1044 VILIGIVSTLSLWAIMP---LLVVFYGAYLYYQNTSREIKRMDSTTRSPVYAQFGEALNGLSSIR 1105

  Fly   950 AFGAQKELIAEFDNYQDMHSSGYYMFLATSRAFGYWLDC-VCVVYIAVITLSFFLFSPENG---- 1009
            |:.|. :.:||. |.:.|.::  ..|...:.|...||.. :.|:...::.|:..|...:||
plant  1106 AYKAY-DRMAEI-NGRSMDNN--IRFTLVNMAANRWLGIRLEVLGGLMVWLTASLAVMQNGKAAN 1166

  Fly  1010 -----GDVGLAITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDLEPEGDFESKPNKKPPKD 1069
                 ..:||.::.|:.:|..:...:|.::..||::.:||||..|.::..|.....: |.:||..
plant  1167 QQAYASTMGLLLSYALSITSSLTAVLRLASLAENSLNSVERVGNYIEIPSEAPLVIE-NNRPPPG 1230

  Fly  1070 WPEDGKIVFDDLSLKYFPDKAADYVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRL-SYNEG 1133
            ||..|.|.|:|:.|:|.|:...  ||..::..|...:|||||||||||||||:|||||: ...:|
plant  1231 WPSSGSIKFEDVVLRYRPELPP--VLHGVSFLISPMDKVGIVGRTGAGKSSLLNALFRIVELEKG 1293

  Fly  1134 AILIDRRDTNDLGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEYSDAKLWESLEEVKLKQVVAD 1198
            .||||..|....||.|||..:.||||.|||||||:|:|||||.|::||.||||||...||..:..
plant  1294 RILIDECDIGRFGLMDLRKVLGIIPQAPVLFSGTVRFNLDPFSEHNDADLWESLERAHLKDTIRR 1358

  Fly  1199 LPSGLQSKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQTTIRNKFKDC 1263
            .|.||.::::|.|.|||||||||:.||||:||.::|||:|||||.||.:||.|||.|||.:||.|
plant  1359 NPLGLDAEVTEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRTDVLIQKTIREEFKSC 1423

  Fly  1264 TVLTIAHRLHTVMDSDKVLVMDAGKAVEFGSPFELLTTSEKKVFHSMVKQTGDSTFDALLKVAQK 1328
            |:|.|||||:|::|.|||||:|:||..||.||..||:..|.. |..||:.||.:..:.|..:..:
plant  1424 TMLIIAHRLNTIIDCDKVLVLDSGKVQEFSSPENLLSNGESS-FSKMVQSTGTANAEYLRSITLE 1487

  Fly  1329 ----------------------------VGLRFKIQCNLSTCLSSLSSFQAHDDNLRLKK 1360
                                        ...:|.:..:|::..:.|.|.:..|||..|||
plant  1488 NKRTREANGDDSQPLEGQRKWQASSRWAAAAQFALAVSLTSSHNDLQSLEIEDDNSILKK 1547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4562	NP_001262747.1	CFTR_protein	12..1300	CDD:273530	459/1328 (35%)
		ABC_membrane	98..367	CDD:294371	75/272 (28%)
		ABCC_MRP_domain1	443..643	CDD:213217	95/200 (48%)
		ABC_membrane	799..1027	CDD:294371	73/245 (30%)
		ABCC_MRP_domain2	1074..1295	CDD:213211	129/221 (58%)
ABCC1	NP_001031116.1	PLN03130	1..1622	CDD:215595	481/1425 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	179	1.000	Domainoid score	I1056
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720