Protein Alignment CG4562 and ABCB24

DIOPT Version :9

• Sequence 1: NP_001262747.1
• Gene: CG4562 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Sequence 2: NP_194591.1
• Gene: ABCB24 / 828980
• AraportID: AT4G28620
• Length: 680
• Species: Arabidopsis thaliana
• Alignment Length: 607
• Identity: 147/607 - (24%)
• Similarity: 276/607 - (45%)
• Gaps: 96/607 - (15%)

  Fly   742 IVFAFFC-IGAQVLASGGDIFLSY-------WVNKNGEAERDTFMARLRRAFPETRINADTDPVD 798
            ::.||.| :||:.|    ::.:.:       |::.:...:.:.::           :.|...|..
plant   108 VISAFACLVGAKFL----NVQVPFLFKVAIDWLSSSSFVDSNPYL-----------VAAFATPSS 157

  Fly   799 IYYFTGINVS-VIIFSLVRSMLFFYLAMRSSTTLHNTMFQGVTRAAMHFF---NTNPSGRILNRF 859
            :....||..| ...|:.:|:.:|..:|:|:..|:...:...:....:.:.   :|....||::|.
plant   158 VLIGYGIARSGSSAFNELRTSVFSKVALRTIRTISRKVLSRLHDLDLRYHLNRDTGALNRIIDRG 222

  Fly   860 SKDLGQVDEILPSVMMDVMQIFLAIVGIVVVLCII----NVWYILATVFLV---IVFYLLRVFYL 917
            |:   .::.||.:::.::|.   .|:.|.:|.||:    ...|.|.|...|   |.|.|     .
plant   223 SR---AINTILSAMVFNIMP---TILEISMVSCILAYKFGAVYALITCLSVGSYIAFTL-----A 276

  Fly   918 STSRDVKRLEAVTRSPIYSHLSA--SLNGLATIRAFGAQKELIAEFD----NYQD--MHSSGYYM 974
            .|...:|..:|:..:...:...|  ||....|::.|..:.....::|    ||:|  :.|...:.
plant   277 MTQWRIKIRKAMNEAENDASTRAIDSLINYETVKYFNNEDYEARKYDQLHENYEDAALQSRKSFA 341

  Fly   975 FLATSRAFGYWLDCVCVVYIAVITLSFFLFSP--ENG----GDV----GLAITQAMGM--TGMVQ 1027
            .|...::|         ::...::.:..|.|.  .||    ||:    ||....::.:  .|:|.
plant   342 LLNFGQSF---------IFSTALSTAMVLCSQGIMNGQMTVGDLVMVNGLLFQLSLPLYFLGVVY 397

  Fly  1028 WGMRQSAELENTMTAVERVVEYEDLEPEGDFESKP-NKKPPKDWPEDGKIVFDDLSLKYFPDKAA 1091
                    .:.....|:....::.||...|...|. ::|.|....:.|.|.|:::...|.|::.
plant   398 --------SDTVQGLVDMKSMFKFLEERSDIGDKDIDRKLPPLVLKGGSISFENVHFSYLPERK- 453

  Fly  1092 DYVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFR-LSYNEGAILIDRRDTNDLGLHDLRSKIS 1155
              :|..::..:...:.|.|||.:|:|||:::..:|| ...:.|.:.||.:|..::.|..|||.|.
plant   454 --ILDGISFEVPAGKSVAIVGSSGSGKSTILRMIFRFFDVDSGNVKIDGQDIKEVRLESLRSSIG 516

  Fly  1156 IIPQEPVLFSGTMRYNLDPFDEY-----SDAKLWESLEEVKLKQVVADLPSGLQSKISEGGTNFS 1215
            ::||:.|||:.|:.:|:    .|     ::.:::.:.....:...:...|....:.:.|.|...|
plant   517 VVPQDTVLFNDTIFHNI----HYGNLSATEEEVYNAARRAAIHDTIMKFPDKYSTAVGERGLMLS 577

  Fly  1216 VGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQTTIRNKFKDCTVLTIAHRLHTVMDSDK 1280
            .|::|.|.||||.|:...||:.||||:.:|.:|:|.|..|:|:...:.|.:.|||||.|.|..|:
plant   578 GGEKQRVALARAFLKSPAILLCDEATSALDSKTEAEIMKTLRSLASNRTCIFIAHRLTTAMQCDE 642

  Fly  1281 VLVMDAGKAVEFGSPFELLTTS 1302
            :|||:.||.||.|:...||..|
plant   643 ILVMEKGKVVEKGTHEVLLGKS 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4562	NP_001262747.1	CFTR_protein	12..1300	CDD:273530	145/603 (24%)
		ABC_membrane	98..367	CDD:294371
		ABCC_MRP_domain1	443..643	CDD:213217
		ABC_membrane	799..1027	CDD:294371	53/258 (21%)
		ABCC_MRP_domain2	1074..1295	CDD:213211	74/226 (33%)
ABCB24	NP_194591.1	ABC_membrane	112..390	CDD:294371	60/312 (19%)
		ATM1	175..673	CDD:227590	134/525 (26%)
		ABCC_ATM1_transporter	439..674	CDD:213220	76/233 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910