Protein Alignment Mrp5 and ABCC14

DIOPT Version :10

• Sequence 1: NP_001262747.1
• Gene: Mrp5 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Sequence 2: NP_191829.1
• Gene: ABCC14 / 825444
• AraportID: AT3G62700
• Length: 1539
• Species: Arabidopsis thaliana
• Alignment Length: 1382
• Identity: 448/1382 - (32%)
• Similarity: 736/1382 - (53%)
• Gaps: 158/1382 - (11%)

  Fly     5 KADELPENPREKSNIFSSLMF------CFAMPTFFKGRKKTLDENDLYRALQEHRSDHLGSKLSA 63
            |::::.....|..::::|..|      .:..|...||.|..|:.:.:.....|||::.|.:...:
plant   235 KSNDVVVEKSENVSLYASASFISKTFWLWMNPLLRKGYKSPLNLDQVPTLSPEHRAEKLATLFES 299

  Fly    64 AWEKEVEKKRKKKKTPSLLKASMNVFGWRLAGLGLVLFILEIGFRVTQPLFLGGLVAYYADASNQ 128
            .|.|..|..|...:| :|::..     |:......||.|:.:......|:    |:..:.|.::.
plant   300 KWPKPQENSRNPVRT-TLIRCF-----WKEIAFTAVLAIIRLSVIYVGPV----LIQSFVDFTSG 354

  Fly   129 EGDNQTKAYLYALGVILTSACNVLFMHPYMLGMFHIGMKARIAMTSMIYRKALRLSRTALGDTTI 193
            :..:.::.|...|.:::.....||..|.:......:||..|..:.:.:|:|.|:|:.:|..:..:
plant   355 KRSSPSQGYYLVLILLIAKFVEVLSTHQFNFNSQKLGMLIRSTLITALYKKGLKLTGSARQNHGV 419

  Fly   194 GQVVNLISNDVGRLDVSVIHMNYLWLGPVEIGIITYLMYREIG---ISAFFGVAVMLLFIPLQAY 255
            ||:||.::.|..:|...::.::.:||.|:::.....|:|..:|   ::...|:..:.:||.|..
plant   420 GQIVNYMAVDAQQLSDMMLQLHAIWLMPLQVAAAIVLLYNTLGPSVVTTVIGLTGIFVFILLGT- 483

  Fly   256 LGKKTSVLRLKTALRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRG 320
              |:.:..:....:..|.|::..||:::.::|||..|||..|::.|...|..|...:....|
plant   484 --KRNNRYQFSLMMNRDSRMKATNEMLNYMRVIKFQAWEDHFNERILKFREMEFGWLSKFLY--- 543

  Fly   321 TLQSFIMFVTRISVFVSLVGF---VLLGKLLTAEKAFVITAYYNILRNTMTVYFPMGISQFAELL 382
            ::...|:.:....|.:|.:.|   |.||..|.|...|..|..:.||:..:.. ||..:...::.:
plant   544 SIAGNIIVLWSTPVLISALTFTTAVFLGVKLDAGTVFTTTTIFKILQEPIRT-FPQSMISLSQAM 607

  Fly   383 VSIRRIQTFMLHEETKVRDKSEDLDEQKLGKAGLIAEPTVAQTTGVLKPSSRRTSEAEHSIVISK 447
            :|:.|:..:|:.     |:.||:..|:..|..|.:|                        :.|..
plant   608 ISLGRLDAYMMS-----RELSEETVERSQGCDGNVA------------------------VEIKD 643

  Fly   448 LKAKWDQKNTDNTLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGSVKVNGTLSYAS 512
            ....||.::.:..::||:.:.|..:|.|::|.||||||||:.:||||::..||.|:|.||.:|.:
plant   644 GSFSWDDEDDEPAIENINFEVKKGELAAIVGTVGSGKSSLLASVLGEMHKLSGKVRVCGTTAYVA 708

  Fly   513 QEPWLFTGTVRQNILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASLSGGQKARIS 577
            |..|:..|||:.||||||||::.:|..|:|.|.||:|.:::.:.|:|.:||||.:||||||.||.
plant   709 QTSWIQNGTVQDNILFGLPMNRSKYNEVLKVCCLEKDMQIMEFGDQTEIGERGINLSGGQKQRIQ 773

  Fly   578 LARAVYRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQADVIVIMDKG 642
            ||||||:::|:|||||..||||.|.|..:|.:|:||.|:.:.:||||||:.||...|.|::|..|
plant   774 LARAVYQESDVYLLDDVFSAVDAHTGSDIFKKCVRGALKGKTILLVTHQVDFLHNVDRILVMRDG 838

  Fly   643 KISAMGTYESMAKSGLDFAQMLT--DPSKKDEGAGDAPDKKSLSRQNSKLRDRHGSI-------- 697
            .|...|.|:.:..|||||.:::.  :.|.:...||.|....:.....|.:..|..||
plant   839 MIVQSGKYDELVSSGLDFGELVAAHETSMELVEAGSASATAANVPMASPITQRSISIESPRQPKS 903

  Fly   698 ------SSMES--AAESLAAESP------------------------MQTQEGRVEGRIGMKLYK 730
                  :||||  ...:.:.|||                        :..:|.|..|::..::||
plant   904 PKVHRTTSMESPRVLRTTSMESPRLSELNDESIKSFLGSNIPEDGSRLIKEEEREVGQVSFQVYK 968

  Fly   731 KYFGANGYGLF--IVFAFFCIGAQVLASGGDIFLSYWVNKNGEAERD-TFMARLRRAFPETRINA 792
            .| ....||.:  |:..||.:..|......|.:|:|..:...|...| |...|:
plant   969 LY-STEAYGWWGMILVVFFSVAWQASLMASDYWLAYETSAKNEVSFDATVFIRV----------- 1021

  Fly   793 DTDPVDIYYFTGINVSVIIFSLVRSMLFFYLAMRSSTTLHNTMFQGVTRAAMHFFNTNPSGRILN 857
                    |.....||:::..| |:....:|.::::......:...:..|.|.||:|.||||||:
plant  1022 --------YVIIAAVSIVLVCL-RAFYVTHLGLKTAQIFFKQILNSLVHAPMSFFDTTPSGRILS 1077

  Fly   858 RFSKDLGQVDEILPSVMMDVMQIFLAIVGIVVVLCIINVWYILATVFLVI------VFYLLRVFY 916
            |.|.|...||..:|.::..|..::..::.|.:|.|    .|...|||.:|      ::|  |.:|
plant  1078 RASTDQTNVDIFIPFMIGLVATMYTTLLSIFIVTC----QYAWPTVFFIIPLGWLNIWY--RGYY 1136

  Fly   917 LSTSRDVKRLEAVTRSPIYSHLSASLNGLATIRAFGAQKELIAEFDNYQ--------DMHSSGYY 973
            |::||::.||:::|::|:..|.|.|:.|:.|||||  :|:.:...:|.:        |.|::|..
plant  1137 LASSRELTRLDSITKAPVIHHFSESIAGVMTIRAF--KKQPMFRQENVKRVNANLRMDFHNNGSN 1199

  Fly   974 MFLA-TSRAFGYWLDCVCVVYIAVITLSFFLFSPENGGDVGLAITQAMGMTGMVQWGMRQSAELE 1037
            .:|. .....|.|:.|:..:::.::..:  :..|||   |||:::..:.:.|::.|.:..|..:|
plant  1200 EWLGFRLELIGSWVLCISALFMVMLPSN--IIKPEN---VGLSLSYGLSLNGVLFWAIYLSCFIE 1259

  Fly  1038 NTMTAVERVVEYEDLEPEGDFESKPNKKPPKDWPEDGKIVFDDLSLKYFPDKAADYVLRSLNIAI 1102
            |.|.:|||:.::.|:..|..:|.| ..:||.:||..|.|..:|:.::|.|:  ...||:.|.|.|
plant  1260 NKMVSVERIKQFTDIPAEAKWEIK-ESRPPPNWPYKGNIRLEDVKVRYRPN--TPLVLKGLTIDI 1321

  Fly  1103 EGCEKVGIVGRTGAGKSSLINALFRL-SYNEGAILIDRRDTNDLGLHDLRSKISIIPQEPVLFSG 1166
            :|.||:|:|||||:|||:||..|||| ..:.|.|:||..|...||||||||:..|||||||||.|
plant  1322 KGGEKIGVVGRTGSGKSTLIQVLFRLVEPSGGKIIIDGIDICTLGLHDLRSRFGIIPQEPVLFEG 1386

  Fly  1167 TMRYNLDPFDEYSDAKLWESLEEVKLKQVVADLPSGLQSKISEGGTNFSVGQRQLVCLARAILRE 1231
            |:|.|:||.::|||.::|:|||..:||.|||..|..|.|.:::.|.|:|||||||:||.|.:|:.
plant  1387 TVRSNIDPTEKYSDEEIWKSLERCQLKDVVASKPEKLDSLVADNGENWSVGQRQLLCLGRVMLKR 1451

  Fly  1232 NRILVMDEATANVDPQTDALIQTTIRNKFKDCTVLTIAHRLHTVMDSDKVLVMDAGKAVEFGSPF 1296
            :|||.:|||||:||.||||:||..||..|.|||:::||||:.||||.|:|||:|||||.|:.||.
plant  1452 SRILFLDEATASVDSQTDAMIQKIIREDFSDCTIISIAHRIPTVMDCDRVLVIDAGKAKEYDSPV 1516

  Fly  1297 ELLTTSEKKVFHSMVKQ 1313
            .||  ..:.:|.::|::
plant  1517 RLL--ERQSLFAALVQE 1531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrp5	NP_001262747.1	MRP_assoc_pro	79..1315	CDD:188098	430/1302 (33%)
ABCC14	NP_191829.1	MRP_assoc_pro	142..1534	CDD:188098	448/1382 (32%)