Protein Alignment Mrp5 and ABCC10

DIOPT Version :10

• Sequence 1: NP_001262747.1
• Gene: Mrp5 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Sequence 2: NP_191473.2
• Gene: ABCC10 / 825083
• AraportID: AT3G59140
• Length: 1453
• Species: Arabidopsis thaliana
• Alignment Length: 1328
• Identity: 428/1328 - (32%)
• Similarity: 700/1328 - (52%)
• Gaps: 124/1328 - (9%)

  Fly    16 KSNIFSSLMFCFAMPTFFKGRKKTLDENDLYRALQEHRSDHLGSKLSAAWEKEVEKKRKKKKT-- 78
            |:.:||:|.|.:......:|..|.|:|.|:....:|.|::...|...   |..:|:||:...:
plant   209 KAGLFSTLSFWWLNSLIKRGNVKDLEEEDIPELRKEERAETCYSLFE---ENLIEQKRRLGSSCQ 270

  Fly    79 PSLLKASMNVFGWR-LAGLGLVLFILEIGFRVTQPLFLGG--LVAYYADASNQEGDNQTKAYLYA 140
            ||:||.:: :..|| |...|...| ::|......||.|..  |||        ||:...:.....
plant   271 PSILKVTV-LCVWRELLTSGFFAF-MKIVAVSAGPLLLNAFILVA--------EGNASFRYEGLV 325

  Fly   141 LGVIL--TSACNVLFMHPYMLGMFHIGMKARIAMTSMIYRKALRLSRTALGDTTIGQVVNLISND 203
            |.|:|  :.....|....:......:|::.|..:|:.|.:|.|||:.::....:..:::|..:.|
plant   326 LAVLLFFSKMIESLSQRQWYFRCRIVGLRVRSLLTAAINKKQLRLNNSSRLIHSGSEIMNYATVD 390

  Fly   204 VGRLDVSVIHMNYLWLGPVEIGIITYLMYREIGISAFFGVAVMLLFIPLQAYLGKKTSVLRLKTA 268
            ..|:.......:.||....::.|...:::..:|::.|..:||::|.:...|.:.|..:..:.:..
plant   391 AYRIGEFPYWFHQLWTTSFQLLIALGILFHSVGVATFSALAVIILTVLCNAPIAKLQNKFQSELM 455

  Fly   269 LRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRGTLQSFIMFVTRIS 333
            ...|||::..||.:..::|:|:||||..|.|:|..:|..|:.:::.|. :|....:.:.:.:  .
plant   456 TSQDERLKACNESLVNMKVLKLYAWESHFKKVIEKLRNIELKSLKAVQ-MRKAYNAVLFWSS--P 517

  Fly   334 VFVSLVGFV---LLGKLLTAEKAFVITAYYNILRNTMTVYFPMGISQFAELLVSIRRIQTFMLHE 395
            ||||...|.   .|...|.|...|...|...::::.:.: .|..|....:..|:..||.||:...
plant   518 VFVSAATFATCYFLDIPLRASNVFTFVATLRLVQDPVRM-IPDVIGVTIQAKVAFSRIATFLEAP 581

  Fly   396 ETKVRDKSEDLDEQKLGKAGLIAEPTVAQTTGVLKPSSRRTSEAEHSIVISKLKAKWDQK-NTDN 459
            |.:                            |..:...:|:...:::|:|......|::| :|..
plant   582 ELQ----------------------------GGERRRKQRSEGNQNAIIIKSASFSWEEKGSTKP 618

  Fly   460 TLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGSVKVNGTLSYASQEPWLFTGTVRQ 524
            .|.|:||:.|..:.|||.|.||||||:|:.|:|||....||::...||::|.||..|:.|||:|.
plant   619 NLRNVSLEVKFGEKVAVCGEVGSGKSTLLAAILGETPCVSGTIDFYGTIAYVSQTAWIQTGTIRD 683

  Fly   525 NILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASLSGGQKARISLARAVYRKADIY 589
            |||||..||:||||..:::.:|::|.||||..|:|.:||||.:||||||.||.||||:|:.||||
plant   684 NILFGGVMDEHRYRETIQKSSLDKDLELLPDGDQTEIGERGVNLSGGQKQRIQLARALYQDADIY 748

  Fly   590 LLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQADVIVIMDKGKISAMGTYESMA 654
            |||||.||||.|....||.:.:...|..:.|||||||:.||...|.:::|..|:|:...||:.:.
plant   749 LLDDPFSAVDAHTASSLFQEYVMDALAGKAVLLVTHQVDFLPAFDSVLLMSDGEITEADTYQELL 813

  Fly   655 KSGLDFAQMLTDPSKKDEG-----AGDAPDK--KSLSRQNSKLRDRHGSISSMESAAESLAAESP 712
            ....|| |.|.:..::..|     |.:.|.|  |.::|              :.|:...:...|.
plant   814 ARSRDF-QDLVNAHRETAGSERVVAVENPTKPVKEINR--------------VISSQSKVLKPSR 863

  Fly   713 MQTQEGRVEGRIGMKLYKKYFGAN-GYGLFIVFAFFCIGAQVLASGGDIFLSYWVNKNGEAERDT 776
            :..||.|.:|..|::.|.:|...| ||    :|.|....|||..:.|.|..:.|:
plant   864 LIKQEEREKGDTGLRPYIQYMNQNKGY----IFFFIASLAQVTFAVGQILQNSWM---------- 914

  Fly   777 FMARLRRAFPETRINADTDPVD----IYYFTGINVSVIIFSLVRSMLFFYLAMRSSTTLHNTMFQ 837
                        ..|.|...|.    |..:..|.:..::..:|||:....:.|:||.:|.:.:..
plant   915 ------------AANVDNPQVSTLKLILVYLLIGLCSVLCLMVRSVCVVIMCMKSSASLFSQLLN 967

  Fly   838 GVTRAAMHFFNTNPSGRILNRFSKDLGQVDEILPSVMMDVMQIFLAIVGIVVVLCIINVWYIL-A 901
            .:.||.|.|:::.|.||||:|.|.||..||..:|..::.|:...:.....:.||.|: .|.:| .
plant   968 SLFRAPMSFYDSTPLGRILSRVSSDLSIVDLDVPFGLIFVVASSVNTGCSLGVLAIV-TWQVLFV 1031

  Fly   902 TVFLVIVFYLLRVFYLSTSRDVKRLEAVTRSPIYSHLSASLNGLATIRAFGAQKELIAEFDNYQD 966
            :|.:|.:.:.|:.:|..|::::.|:...|||.:.:||:.|:.|..|||||..::....:.....|
plant  1032 SVPMVYLAFRLQKYYFQTAKELMRINGTTRSYVANHLAESVAGAITIRAFDEEERFFKKSLTLID 1096

  Fly   967 MHSSGYYMFLATSRAFGYWLDCVCVVYIA-----VITLSFFLFSPENGGDVGLAITQAMGMTGMV 1026
            .::|.::...|.:......|:.|..:.:|     :|.|....||   .|.:|:|::..:.:...:
plant  1097 TNASPFFHSFAANEWLIQRLETVSAIVLASTAFCMILLPTGTFS---SGFIGMALSYGLSLNMGL 1158

  Fly  1027 QWGMRQSAELENTMTAVERVVEYEDLEPEGDFESKPNKKPPKDWPEDGKIVFDDLSLKYFPDKAA 1091
            .:.::....|.|.:.:|||:.:|..|.||.. |.....:||.:||..|::...||.::|  .:.:
plant  1159 VYSVQNQCYLANWIISVERLNQYTHLTPEAP-EVIEETRPPVNWPVTGRVEISDLQIRY--RRES 1220

  Fly  1092 DYVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRLSYNEGA-ILIDRRDTNDLGLHDLRSKIS 1155
            ..||:.::...||..|:|||||||:||::||:|||||....|. |::|..|.:.:|:|||||:..
plant  1221 PLVLKGISCTFEGGHKIGIVGRTGSGKTTLISALFRLVEPVGGKIVVDGVDISKIGVHDLRSRFG 1285

  Fly  1156 IIPQEPVLFSGTMRYNLDPFDEYSDAKLWESLEEVKLKQVVADLPSGLQSKISEGGTNFSVGQRQ 1220
            ||||:|.||:||:|:||||..::|||::||.|.:.:||:||.:..:||.|.:.|.|:|:|:||||
plant  1286 IIPQDPTLFNGTVRFNLDPLCQHSDAEIWEVLGKCQLKEVVQEKENGLDSLVVEDGSNWSMGQRQ 1350

  Fly  1221 LVCLARAILRENRILVMDEATANVDPQTDALIQTTIRNKFKDCTVLTIAHRLHTVMDSDKVLVMD 1285
            |.||.||:||.:|:||:|||||::|..||.::|.|||.:|.||||:|:|||:.||||...||.:.
plant  1351 LFCLGRAVLRRSRVLVLDEATASIDNATDLILQKTIRREFADCTVITVAHRIPTVMDCTMVLSIS 1415

  Fly  1286 AGKAVEFGSPFELLTTSEKKVFHSMVKQ 1313
            .|:.||:..|.:|: ..|..:|..:||:
plant  1416 DGRIVEYDEPMKLM-KDENSLFGKLVKE 1442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrp5	NP_001262747.1	MRP_assoc_pro	79..1315	CDD:188098	411/1263 (33%)
ABCC10	NP_191473.2	MRP_assoc_pro	194..1437	CDD:188098	425/1321 (32%)