Protein Alignment CG4562 and ABCG37

DIOPT Version :9

• Sequence 1: NP_001262747.1
• Gene: CG4562 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Sequence 2: NP_190916.1
• Gene: ABCG37 / 824516
• AraportID: AT3G53480
• Length: 1450
• Species: Arabidopsis thaliana
• Alignment Length: 1093
• Identity: 221/1093 - (20%)
• Similarity: 400/1093 - (36%)
• Gaps: 306/1093 - (27%)

  Fly   380 ELLVSIRR--------IQTF-MLHEETKVRDKSEDLDEQKLGKAGLIAEPTVAQT-----TGVLK 430
            :||..|||        :.|. :.:|..||..:.|.::    ||    |.||:..|     :.::|
plant   120 KLLKKIRRRIDRVGMELPTIEVRYESLKVVAECEVVE----GK----ALPTLWNTAKRVLSELVK 176

  Fly   431 PSSRRTSEAEHSIVISKLKAKWDQKNTDNTLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGEL 495
            .:..:|.||:.:|:              |.::.|   .||.:|..::||...||::|::|:.|.|
plant   177 LTGAKTHEAKINII--------------NDVNGI---IKPGRLTLLLGPPSCGKTTLLKALSGNL 224

  Fly   496 NPD---SGSVKVNG----------TLSYASQ-EPWLFTGTVRQNILFGLPMDKHRYRT-----VV 541
            ..:   ||.:..||          |.:|.|| :..:...|||:.:.|.........||     |.
plant   225 ENNLKCSGEISYNGHRLDEFVPQKTSAYISQYDLHIAEMTVRETVDFSARCQGVGSRTDIMMEVS 289

  Fly   542 KR-------------------------CALERDFEL----LPYADKTIVGE---RGASLSGGQKA 574
            ||                         .:|:.|:.|    |....:.::|:   ||  :|||||.
plant   290 KREKEKGIIPDTEVDAYMKAISVEGLQRSLQTDYILKILGLDICAEILIGDVMRRG--ISGGQKK 352

  Fly   575 RISLARAVYRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQA----DV 635
            |::.|..:........:|:..:.:|:.....:. :.::.|.......::...||...::    |.
plant   353 RLTTAEMIVGPTKALFMDEITNGLDSSTAFQIV-KSLQQFAHISSATVLVSLLQPAPESYDLFDD 416

  Fly   636 IVIMDKGKI-------SAMGTYESMA------KSGLDFAQMLTDPSKKDEGA----GDAP-DKKS 682
            |::|.||:|       ..:..:|...      |...||.|.:.  ||||:..    .|.| ...|
plant   417 IMLMAKGRIVYHGPRGEVLNFFEDCGFRCPERKGVADFLQEVI--SKKDQAQYWWHEDLPYSFVS 479

  Fly   683 LSRQNSKLRDRHGSISSMESAAESLAAESPMQTQEGRVEGRIGMKLYKKYFGANGYGLFIVFAFF 747
            :...:.|.:|    :|..:...::|:  .|....:...:.     |....:....:.|||.
plant   480 VEMLSKKFKD----LSIGKKIEDTLS--KPYDRSKSHKDA-----LSFSVYSLPNWELFIA---- 529

  Fly   748 CIGAQVLASGGDIFLSYWVNKNGEAERDTFMARLRRAFPETRINADTDPVDIYYFTGINVSVIIF 812
            ||..:.|....:.|:  ::.|..:.....|:.  ...|..||:..|....:.|      :|.:.|
plant   530 CISREYLLMKRNYFV--YIFKTAQLVMAAFIT--MTVFIRTRMGIDIIHGNSY------MSALFF 584

  Fly   813 SLV----------------------RSMLFFYLAMR---SSTTLH--NTMFQGVTRAAMHFF--- 847
            :|:                      :..|.||.|..   .:|.|.  .:.|:.:....:.::
plant   585 ALIILLVDGFPELSMTAQRLAVFYKQKQLCFYPAWAYAIPATVLKVPLSFFESLVWTCLSYYVIG 649

  Fly   848 NTNPSGRILNRFSKDLGQVDEILPSVMMDVMQIFLAIVGIVVVLCIINVWYILATVFLVIV---- 908
            .|..:.|...:|                        |:...|....|:::..||.:|..:|
plant   650 YTPEASRFFKQF------------------------ILLFAVHFTSISMFRCLAAIFQTVVASIT 690

  Fly   909 ---FYLLRVFYLS------TSRDVKRLEAVTRSPI-YSHLSASLNGLATIRAFGAQKELIAEFDN 963
               |.:|..|..:      .|...........:|: |..:..|:|      .|.|.:....:.:|
plant   691 AGSFGILFTFVFAGFVIPPPSMPAWLKWGFWANPLSYGEIGLSVN------EFLAPRWNQMQPNN 749

  Fly   964 Y---------QDMHSSGYYMFLATSRAFGYWLDCVCVVYIAVITLSF-FLFSPENGGDVGLAITQ 1018
            :         :.|..:||..:::.....|:     .|::..:.||:. ||.||          |.
plant   750 FTLGRTILQTRGMDYNGYMYWVSLCALLGF-----TVLFNIIFTLALTFLKSP----------TS 799

  Fly  1019 AMGMTGMVQWGMRQSAELENTMTAVERVVEYEDLEPEGDFESKPNKKPPKDWPEDGKIV------ 1077
            :..|.     ...:.:||:.|..:.|          :.....|....|.|...||..::
plant   800 SRAMI-----SQDKLSELQGTEKSTE----------DSSVRKKTTDSPVKTEEEDKMVLPFKPLT 849

  Fly  1078 --FDDLSLKYFPDKAAD-----YVLRSLNIA--IEGCEKVGI----VGRTGAGKSSLINALF--- 1126
              |.||:  ||.|...:     |..:.|.:.  |.|..:.||    :|.:||||::|::.|.
plant   850 VTFQDLN--YFVDMPVEMRDQGYDQKKLQLLSDITGAFRPGILTALMGVSGAGKTTLLDVLAGRK 912

  Fly  1127 RLSYNEGAILID---------RRDTNDLGLHDLRSKISIIPQEPVLFSGTMRYNLDP-FDEYSDA 1181
            ...|.||.|.|.         .|.:......|:.|. :|..:|.|::|..:|  |.| .|..:..
plant   913 TSGYIEGDIRISGFPKVQETFARVSGYCEQTDIHSP-NITVEESVIYSAWLR--LAPEIDATTKT 974

  Fly  1182 K-LWESLEEVKLKQVVADLPSGLQSKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVD 1245
            | :.:.||.::|.::...|..      ..|.:..|..||:.:.:|..::....|:.|||.|..:|
plant   975 KFVKQVLETIELDEIKDSLVG------VTGVSGLSTEQRKRLTIAVELVANPSIIFMDEPTTGLD 1033

  Fly  1246 PQTDALIQTTIRN-----KFKDCTVLTIAHRLHTVMDSDKVLVMDAGKAVEFG 1293
            .:..|::...::|     :...||:...:..:....| :.||:...|:.:..|
plant  1034 ARAAAIVMRAVKNVADTGRTIVCTIHQPSIDIFEAFD-ELVLLKRGGRMIYTG 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4562	NP_001262747.1	CFTR_protein	12..1300	CDD:273530	221/1093 (20%)
		ABC_membrane	98..367	CDD:294371
		ABCC_MRP_domain1	443..643	CDD:213217	54/254 (21%)
		ABC_membrane	799..1027	CDD:294371	45/281 (16%)
		ABCC_MRP_domain2	1074..1295	CDD:213211	60/258 (23%)
ABCG37	NP_190916.1	PLN03140	54..1450	CDD:215599	221/1093 (20%)
		ABC_trans_N	89..167	CDD:291196	15/54 (28%)
		ABCG_PDR_domain1	186..429	CDD:213200	56/262 (21%)
		ABC2_membrane	530..735	CDD:279410	38/238 (16%)
		PDR_assoc	742..804	CDD:285559	13/76 (17%)
		ABCG_PDR_domain2	847..1085	CDD:213199	59/249 (24%)
		ABC2_membrane	1180..1387	CDD:279410

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000