Protein Alignment Mrp5 and CG31793

DIOPT Version :10

• Sequence 1: NP_001262747.1
• Gene: Mrp5 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Sequence 2: NP_609930.4
• Gene: CG31793 / 326161
• FlyBaseID: FBgn0051793
• Length: 1307
• Species: Drosophila melanogaster
• Alignment Length: 1342
• Identity: 825/1342 - (61%)
• Similarity: 1023/1342 - (76%)
• Gaps: 60/1342 - (4%)

  Fly     4 MKADELPENPREKSNIFSSLMFCFAMPTFFKGRKKTLDENDLYRALQEHRSDHLGSKLSAAWEKE 68
            |:|.:||.||||.:.|.||||||||:|..|||||:||...|||:.|.||.:..||.:....||.|
  Fly     1 MQASKLPPNPRESAGILSSLMFCFALPILFKGRKQTLQPTDLYKTLNEHEAASLGDEFFQGWEDE 65

  Fly    69 VEKKRKK---KKTPSLLKASMNVFGWRLAGLGLVLFILEIGFRVTQPLFLGGLVAYYADASNQEG 130
            |.:.|:|   .:.||:|:....||||||...|:.:..||:|.|.|.||.|.||::.:::..|...
  Fly    66 VARCRRKGDSGRKPSVLRVIGRVFGWRLIMSGITIAALELGTRATVPLLLAGLISEFSEHGNGHS 130

  Fly   131 DNQTKAYLYALGVILTSACNVLFMHPYMLGMFHIGMKARIAMTSMIYRKALRLSRTALGDTTIGQ 195
            .|   |.:||:.:|.....:||..||||:||.|:.||.|:|::|.|||||||||||:||.||.||
  Fly   131 YN---AQIYAVLLIACILASVLLTHPYMMGMMHLAMKMRVAVSSAIYRKALRLSRTSLGGTTTGQ 192

  Fly   196 VVNLISNDVGRLDVSVIHMNYLWLGPVEIGIITYLMYREIGISAFFGVAVMLLFIPLQAYLGKKT 260
            ||||:|||:.|.|..:||.::|||||:|:.|.:|.:|.:||:::|:|:::::|::|||.||.:.|
  Fly   193 VVNLLSNDLNRFDRCLIHFHFLWLGPLELLIASYFLYEQIGMASFYGISILVLYLPLQTYLSRVT 257

  Fly   261 SVLRLKTALRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRGTLQSF 325
            |.|||:||||||:||||||||||||||||||.||.||.|:|..:|..||::||.:|.:||.|.||
  Fly   258 SKLRLQTALRTDQRVRMMNEIISGIQVIKMYTWERPFGKLIGQMRRSEMSSIRQMNLLRGILLSF 322

  Fly   326 IMFVTRISVFVSLVGFVLLGKLLTAEKAFVITAYYNILRNTMTVYFPMGISQFAELLVSIRRIQT 390
            .:.:.||::||||:||||.|..||||:||.:||:|||||.|::.:||.|:|||||||||:|||..
  Fly   323 EITLGRIAIFVSLLGFVLGGGELTAERAFCVTAFYNILRRTVSKFFPSGMSQFAELLVSMRRITN 387

  Fly   391 FMLHEETKVRDKSEDLDEQKLGKAGLIAEPTVAQTTGVLKPSSRRT------SEAEHSIVISKLK 449
            ||:.||..|.|.||..||:        ||    :...:||...:|:      .|.:..:.|..|:
  Fly   388 FMMREEANVIDMSERRDEK--------AE----EEQHLLKEVEKRSYPVGIGKEPDTLVEIKALR 440

  Fly   450 AKWDQKNTDNTLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGSVKVNGTLSYASQE 514
            |:|.|:..|..|:|:::..:..|||||||||||||||||||:||||.|:||||:|:|..||||||
  Fly   441 ARWGQEQHDLVLNNVNMSLRRGQLVAVIGPVGSGKSSLIQAILGELPPESGSVQVSGKYSYASQE 505

  Fly   515 PWLFTGTVRQNILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASLSGGQKARISLA 579
            ||||..:||.||||||||||.|||||:||||||||.||| :.|.||||||||||||||:|||.||
  Fly   506 PWLFNASVRDNILFGLPMDKQRYRTVLKRCALERDLELL-HGDGTIVGERGASLSGGQRARICLA 569

  Fly   580 RAVYRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQADVIVIMDKGKI 644
            |||||:||:||||||||||||||||||||:||||||.:::|:||||||||||.||:|||||||.:
  Fly   570 RAVYRRADVYLLDDPLSAVDTHVGRHLFDECMRGFLGKQLVILVTHQLQFLEDADLIVIMDKGHV 634

  Fly   645 SAMGTYESMAKSGLDFAQMLTDPSKKDEGAGDAPDKKSLSRQNSKL--RDRHGSISSMESAAESL 707
            ||.||||.|.|||.||||:|.:.::...|..:.....:||||:|.|  :..:||.||:||..|.
  Fly   635 SACGTYEEMLKSGQDFAQLLVESTQNSGGGDEIITSPNLSRQSSALSTKSSNGSSSSLESMVEK- 698

  Fly   708 AAESP----MQTQEGRVEGRIGMKLYKKYFGAN-GYGLFIVFAFFCIGAQVLASGGDIFLSYWVN 767
              |.|    :.:||.|..|:||:.:|||||||. |..:|:|....|||.|:||||||.||||||
  Fly   699 --EKPKPSAVSSQESRSGGQIGLSMYKKYFGAGCGVLVFVVLIMLCIGTQILASGGDYFLSYWV- 760

  Fly   768 KNGEAERDTFMARLRRAFPETRINADTDPVDIYYFTGINVSVIIFSLVRSMLFFYLAMRSSTTLH 832
            ||                     .|.:..:||||||.|||.::|.:|:|::|||.:.|.|||.||
  Fly   761 KN---------------------TASSSTLDIYYFTAINVGLVICALLRTLLFFNITMHSSTELH 804

  Fly   833 NTMFQGVTRAAMHFFNTNPSGRILNRFSKDLGQVDEILPSVMMDVMQIFLAIVGIVVVLCIINVW 897
            ||||||::|.|::||:|||||||||||:.|||||||::|:||:|.:||||.:.||:.|||:.|.|
  Fly   805 NTMFQGLSRTALYFFHTNPSGRILNRFANDLGQVDEVMPAVMLDCIQIFLTLTGIICVLCVTNPW 869

  Fly   898 YILATVFLVIVFYLLRVFYLSTSRDVKRLEAVTRSPIYSHLSASLNGLATIRAFGAQKELIAEFD 962
            |::.|..:::.||..|.|||.|||||||||||.|||:|||.||:|.||.||||.|||:.||.::|
  Fly   870 YLINTFAMMLAFYYWRDFYLKTSRDVKRLEAVARSPMYSHFSATLVGLPTIRAMGAQQTLIGQYD 934

  Fly   963 NYQDMHSSGYYMFLATSRAFGYWLDCVCVVYIAVITLSFFLFSP--ENGGDVGLAITQAMGMTGM 1025
            ||||:||||||.|::|||||||:||..||.|:..:.|..| |:|  .|.|.:|||||||:|||||
  Fly   935 NYQDLHSSGYYTFVSTSRAFGYYLDLFCVAYVISVILHNF-FNPPLHNAGQIGLAITQALGMTGM 998

  Fly  1026 VQWGMRQSAELENTMTAVERVVEYEDLEPEGDFESKPNKKPPKDWPEDGKIVFDDLSLKYFPDKA 1090
            |||||||||||||.||:||||:||:||:|||||.|...|:|||.||::||:|..||||:|.||..
  Fly   999 VQWGMRQSAELENAMTSVERVLEYKDLDPEGDFNSPAEKQPPKSWPKEGKLVTKDLSLRYEPDTN 1063

  Fly  1091 ADYVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRLSYNEGAILIDRRDTNDLGLHDLRSKIS 1155
            :..||:.|:..|:..||||||||||||||||||||||||||:||||||..||||:||||||||||
  Fly  1064 SPCVLKGLSFTIQPMEKVGIVGRTGAGKSSLINALFRLSYNDGAILIDSLDTNDIGLHDLRSKIS 1128

  Fly  1156 IIPQEPVLFSGTMRYNLDPFDEYSDAKLWESLEEVKLKQVVADLPSGLQSKISEGGTNFSVGQRQ 1220
            ||||||||||||||||||||::|.|.|||::||:|.||:.:::|||||||.||||||||||||||
  Fly  1129 IIPQEPVLFSGTMRYNLDPFEQYPDDKLWKALEDVHLKEEISELPSGLQSIISEGGTNFSVGQRQ 1193

  Fly  1221 LVCLARAILRENRILVMDEATANVDPQTDALIQTTIRNKFKDCTVLTIAHRLHTVMDSDKVLVMD 1285
            |||||||||||||||||||||||||||||||||.||||||||||||||||||:|:||||||||||
  Fly  1194 LVCLARAILRENRILVMDEATANVDPQTDALIQATIRNKFKDCTVLTIAHRLNTIMDSDKVLVMD 1258

  Fly  1286 AGKAVEFGSPFELLTTSEKKVFHSMVKQTGDSTFDALLKVAQ 1327
            ||..||||||:||||.|:.||||.||.|||.::||.|||||:
  Fly  1259 AGHVVEFGSPYELLTASKAKVFHGMVMQTGKASFDHLLKVAE 1300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrp5	NP_001262747.1	MRP_assoc_pro	79..1315	CDD:188098	777/1250 (62%)
CG31793	NP_609930.4	PLN03130	10..1305	CDD:215595	820/1333 (62%)