| Sequence 1: | NP_001262747.1 | Gene: | CG4562 / 42362 | FlyBaseID: | FBgn0038740 | Length: | 1408 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001028508.2 | Gene: | Abcc4 / 239273 | MGIID: | 2443111 | Length: | 1325 | Species: | Mus musculus |
| Alignment Length: | 1350 | Identity: | 610/1350 - (45%) |
|---|---|---|---|
| Similarity: | 860/1350 - (63%) | Gaps: | 87/1350 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 8 ELPENPREKSNIFSSLMFCFAMPTFFKGRKKTLDENDLYRALQEHRSDHLGSKLSAAWEKEVEKK 72
Fly 73 RKKKKTPSLLKASMNVFGWRLAGLGLVLFILEIGFRVTQPLFLGGLVAYYADASNQEGDNQTKAY 137
Fly 138 LYALGVILTSACNVLFMHPYMLGMFHI---GMKARIAMTSMIYRKALRLSRTALGDTTIGQVVNL 199
Fly 200 ISNDVGRLDVSVIHMNYLWLGPVEIGIITYLMYREIGISAFFGVAVMLLFIPLQAYLGKKTSVLR 264
Fly 265 LKTALRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRGTLQSFIMFV 329
Fly 330 TRISVFVSLVGFVLLGKLLTAEKAFVITAYYNILRNTMTVYFPMGISQFAELLVSIRRIQTFMLH 394
Fly 395 EETKVRDKSEDLDEQKLGKAGLIAEPTVAQTTGVLKPSSRRTSEAEHSIVISKLKAKWDQKNTDN 459
Fly 460 TLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGSVKVNGTLSYASQEPWLFTGTVRQ 524
Fly 525 NILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASLSGGQKARISLARAVYRKADIY 589
Fly 590 LLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQADVIVIMDKGKISAMGTYESMA 654
Fly 655 KSGLDFAQMLTDPSKKDEGA--GDAPDKKSLSRQNSKLRDRHGSISSMESAAESLAAESP----- 712
Fly 713 -----MQTQEGRVEGRIGMKLYKKYFGANGYGLFIVFAFF--CIGAQVLASGGDIFLSYWVNKNG 770
Fly 771 EAERDTFMARLRRAFPETRINAD---TDPVDIYYFTGINVSV----IIFSLVRSMLFFYLAMRSS 828
Fly 829 TTLHNTMFQGVTRAAMHFFNTNPSGRILNRFSKDLGQVDEILPSVMMDVMQIFLAIVGIVVVLCI 893
Fly 894 INVWYILATVFLVIVFYLLRVFYLSTSRDVKRLEAVTRSPIYSHLSASLNGLATIRAFGAQKELI 958
Fly 959 AEFDNYQDMHSSGYYMFLATSRAFGYWLDCVCVVYIAVITL-SFFLFSPENGGDVGLAITQAMGM 1022
Fly 1023 TGMVQWGMRQSAELENTMTAVERVVEYEDLEPEGDFESKPNKKPPKDWPEDGKIVFDDLSLKYFP 1087
Fly 1088 DKAADYVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRLSYNEGAILIDRRDTNDLGLHDLRS 1152
Fly 1153 KISIIPQEPVLFSGTMRYNLDPFDEYSDAKLWESLEEVKLKQVVADLPSGLQSKISEGGTNFSVG 1217
Fly 1218 QRQLVCLARAILRENRILVMDEATANVDPQTDALIQTTIRNKFKDCTVLTIAHRLHTVMDSDKVL 1282
Fly 1283 VMDAGKAVEFGSPFELLTTSEKKVFHSMVKQTGDSTFDALLKVAQKVGLR 1332 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG4562 | NP_001262747.1 | CFTR_protein | 12..1300 | CDD:273530 | 597/1312 (46%) |
| ABC_membrane | 98..367 | CDD:294371 | 111/271 (41%) | ||
| ABCC_MRP_domain1 | 443..643 | CDD:213217 | 111/199 (56%) | ||
| ABC_membrane | 799..1027 | CDD:294371 | 100/232 (43%) | ||
| ABCC_MRP_domain2 | 1074..1295 | CDD:213211 | 139/220 (63%) | ||
| Abcc4 | NP_001028508.2 | PLN03130 | 12..1284 | CDD:215595 | 603/1333 (45%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 657..690 | 8/32 (25%) | |||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:O15439 | 1322..1325 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167841678 | |
| Domainoid | 1 | 1.000 | 232 | 1.000 | Domainoid score | I2403 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0054 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H74563 | |
| Inparanoid | 1 | 1.050 | 1109 | 1.000 | Inparanoid score | I229 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1354 |
| OMA | 1 | 1.010 | - | - | QHG51855 | |
| OrthoDB | 1 | 1.010 | - | - | D138195at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001028 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42331 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100026 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24223 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5383 |
| SonicParanoid | 1 | 1.000 | - | - | X771 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.790 | |||||