Protein Alignment CG4562 and haf-4

DIOPT Version :9

• Sequence 1: NP_001262747.1
• Gene: CG4562 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Sequence 2: NP_001021666.1
• Gene: haf-4 / 171639
• WormBaseID: WBGene00001814
• Length: 787
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 144/554 - (25%)
• Similarity: 261/554 - (47%)
• Gaps: 73/554 - (13%)

  Fly   799 IYYFTGINVSVIIFSLVRSMLFFYLAMRSSTTLHNTMFQGVTRAAMHFFNTNPSGRILNRFSKDL 863
            :|..|.|::...:.:..|...|.|...|....:...:|.|:.:..:.|::.:.:|.:.:|.:.|.
 Worm   223 VYIMTIISLVSAVAAGFRGGSFEYAYARIQRAIRYDLFHGLVKQDVAFYDAHKTGEVTSRLAADC 287

  Fly   864 GQVDEILPSVMMDVMQIFL----AIVGIVVVLCIINVWYILATVFLV-IVFYLLRVFYLSTSRDV 923
            ..:.:   :|.::| .:||    .::|.::.:..::....|.|..|| |:|...::|  .|..|:
 Worm   288 QTMSD---TVALNV-NVFLRNCVMLLGSMIFMMKLSWRLSLVTFILVPIIFVASKIF--GTYYDL 346

  Fly   924 KRLEAVTRSPIYSHLSAS---LNGLATIRAFGAQKELIAEFDNYQDMHSSGYYMFLATSRAFGY- 984
              |...|:..|......:   |:.:.|:|:|..:.   .|.|.:....:  :.:.:..::|..|
 Worm   347 --LSERTQDTIAESNDVAEEVLSTMRTVRSFSCEN---VEADRFYGKLT--HTLDVTRTKAIAYI 404

  Fly   985 ---WLDCVCVVYIAVITLSFFLFSPENGGDVGLAITQAMGMTGMVQW---------GMRQSAE-- 1035
               |:..:...:|.|..|.:       ||.  |.:||.|....:|.:         .:||..|
 Worm   405 GFLWVSELFQSFIIVSVLWY-------GGH--LVLTQKMKGDLLVSFLLYQMQLGDNLRQMGEVW 460

  Fly  1036 --LENTMTAVERVVEYEDLEPE----GDFESKPNKKPPKDWPED--GKIVFDDLSLKYFPDKAAD 1092
              |..::.|..:|.||.|.||:    |::           .||:  |||.|.::...| |.::..
 Worm   461 TGLMQSVGASRKVFEYIDREPQIQHNGEY-----------MPENVVGKIEFRNVHFSY-PTRSDQ 513

  Fly  1093 YVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRLSY-NEGAILIDRRDTNDLGLHDLRSKISI 1156
            .:|:.|:..:|..|.|.:||.:|:||||.|:.|..... |.|.:|:|.....:...|.:..||::
 Worm   514 PILKDLSFTVEPGETVALVGPSGSGKSSCISLLENFYVPNAGQVLVDGVPLEEFEHHYIHKKIAL 578

  Fly  1157 IPQEPVLFSGTMRYNLDPFDEYSDAKLWESLEEVKLKQVVADLPSGLQSKISEGGTNFSVGQRQL 1221
            :.||||||:.::..|:....|.:|.::..|.|.......:.......::.:.|.||..|.||:|.
 Worm   579 VGQEPVLFARSVMENVRYGVEVADTEIIRSCEMANAHGFIMQTTLKYETNVGEKGTQMSGGQKQR 643

  Fly  1222 VCLARAILRENRILVMDEATANVDPQTDALIQTTIRNKFKDCTVLTIAHRLHTVMDSDKVLVMDA 1286
            :.:|||::||..||::||||:.:|.:::.|:|..|.......:|:.|||||.||..:||::|::.
 Worm   644 IAIARALVREPAILLLDEATSALDTESEHLVQEAIYKNLDGKSVILIAHRLSTVEKADKIVVINK 708

  Fly  1287 GKAVEFGSPFELLT----TSEKKVFHSMVKQTGD 1316
            |:..:.|:...||.    |..|.|...|:   ||
 Worm   709 GRVEQIGNHETLLKDTNGTYAKLVQRQMM---GD 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4562	NP_001262747.1	CFTR_protein	12..1300	CDD:273530	137/532 (26%)
		ABC_membrane	98..367	CDD:294371
		ABCC_MRP_domain1	443..643	CDD:213217
		ABC_membrane	799..1027	CDD:294371	48/239 (20%)
		ABCC_MRP_domain2	1074..1295	CDD:213211	73/221 (33%)
haf-4	NP_001021666.1	3a01208	16..732	CDD:273363	140/542 (26%)
		ABC_membrane	189..449	CDD:279056	49/247 (20%)
		ABC_MTABC3_MDL1_MDL2	498..735	CDD:213216	76/237 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910