Protein Alignment CG4562 and abcd1

DIOPT Version :9

• Sequence 1: NP_001262747.1
• Gene: CG4562 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Sequence 2: XP_002935559.1
• Gene: abcd1 / 100493545
• XenbaseID: XB-GENE-953036
• Length: 744
• Species: Xenopus tropicalis
• Alignment Length: 653
• Identity: 120/653 - (18%)
• Similarity: 233/653 - (35%)
• Gaps: 159/653 - (24%)

  Fly   157 YMLGMFHIGMKAR-IAMTSMIYRKALRLSRTALGDTTIGQVVNL----------ISNDVGRLDVS 210
            |:.|...:..:.| :|....:|          .|..|..:|.|:          ::.||.....|
 Frog   158 YLEGQLSLAFRTRLVAHAYQLY----------FGQQTYYRVSNMDGRLRNPDQSLTEDVVAFANS 212

  Fly   211 VIHMNYLWLGPV-EIGIITYLMY---REIGI-----SAFFGVAVMLLFIPLQAYLGKKTSVLRLK 266
            |.|:......|| ::.:.||.:.   :..|.     |...|:.|::....|:: ...|...|..:
 Frog   213 VAHLYSNLTKPVLDVVVTTYTLLSTAKSKGANTAWPSTIAGLVVIITAKVLRS-CSPKFGKLVAE 276

  Fly   267 TALRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRGTLQSFIMFVTR 331
            .|.|..|...|.:.:::..:.|..|..           ...||:.:|.. |...:.|..|:.:.|
 Frog   277 EARRKGELRYMHSRVVANSEEIAFYGG-----------HKVEMSLLRKC-YEDLSSQINIILLER 329

  Fly   332 ISVFVSLVGFVL------LGKLLTAEKAFVITAYYN-----ILRNTMTVYFPMGISQFAELLVSI 385
            : .:|.|..|::      .|.::.|......|.|.:     :.:..|.:.....:|:.||...:.
 Frog   330 L-WYVMLEQFLMKYVWSASGLVMVAVPIITATGYADSDSEEVKKAAMEMKEEELVSERAEAFTTA 393

  Fly   386 RRIQT---------FMLHEE--------TKVRDKSEDLDEQKLG---KAGLIAEPTVAQTTGVLK 430
            |.:.|         ...::|        .:|.|..|..::.:.|   :.|.: |...::..||::
 Frog   394 RNLLTASADAIERVMSSYKEVTELAGYTARVHDMFEVFEDVQKGIYKRPGEL-EEAESKNRGVIQ 457

  Fly   431 PSSR---------RTSEAEHSIVISKLKAKWDQKNTDNTLDNISLKFKPRQLVAVIGPVGSGKSS 486
            ...|         :..:.|:.|:...:...  ....|..::.::::.:....:.:.||.|.||||
 Frog   458 HGIRMEGPLEIKGKVVDVENGIICENIPIV--TPTGDVVVERLNIQVEEGMHLLITGPNGCGKSS 520

  Fly   487 LIQAVLGELNPDSGSVKVNGT---LSYASQEPWLFTGTVRQNILFGLPMDKHRYRTVVKRCALER 548
            |.: :||.|.|....|.....   :.|..|.|::..||:|..:::....:..|.::
 Frog   521 LFR-ILGGLWPAYKGVLYKPPPQHMFYIPQRPYMSVGTLRDQVIYPDTAEDMRRKS--------- 575

  Fly   549 DFELLPYADKTI---------------------VGERGASLSGGQKARISLARAVYRKADIYLLD 592
                  :.||.:                     |.:....||||:|.|:.:||..|.|....|||
 Frog   576 ------FTDKNLEAILNIVNLIYLVQREGGWDSVSDWKDVLSGGEKQRVGMARMFYHKPKYALLD 634

  Fly   593 DPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQADVIVIMDKGKISAMGTYESMAKSG 657
            :..|||...|...:|.......:   .:|.:||:....:....::..|             .:.|
 Frog   635 ECTSAVSIDVEGKIFQAAKDAGI---ALLSITHRPSLWKYHTHLLQFD-------------GEGG 683

  Fly   658 LDFAQMLTDPSKKDEGAGDAPDKKSLSRQNSKLRDRHGSISSME----SAAESLAAESPMQTQEG 718
            ..|.::            |...:.||:.:..:|..:...:..|:    ...:.|..::.:...||
 Frog   684 WKFEKL------------DTAARLSLTEEKQRLEQQLAGVPKMQQRLGELCQLLGEDTEVADTEG 736

  Fly   719 RVE 721
            .|:
 Frog   737 NVD 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4562	NP_001262747.1	CFTR_protein	12..1300	CDD:273530	120/653 (18%)
		ABC_membrane	98..367	CDD:294371	45/240 (19%)
		ABCC_MRP_domain1	443..643	CDD:213217	47/223 (21%)
		ABC_membrane	799..1027	CDD:294371
		ABCC_MRP_domain2	1074..1295	CDD:213211
abcd1	XP_002935559.1	3a01203	11..686	CDD:273360	110/586 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910